Navigation Links
Aging Brain's Decline May Hinge on a Gene
Date:10/25/2011

TUESDAY, Oct. 25 (HealthDay News) -- Researchers have identified a gene variation that seems to have a major effect on the rate at which men experience an age-related decline in intellectual function.

The study included 144 experienced U.S. male pilots over the age of 40 who took a Federal Aviation Administration-approved flight simulator test three times over two years. The participants included recreational pilots, certified flight instructors and airline pilots.

Using blood and saliva samples from the pilots, the researchers also conducted genetic analyses, looking for the gene that produces a protein called brain-derived neurotropic factor (BDNF). The BDNF gene is considered critical to the development and maintenance of the central nervous system. Levels decline gradually with age, but the findings of this study suggest that a variant of the gene hastens that process.

To test their theory, the researchers divided the pilots into two groups -- those with at least one copy of a BDNF gene that contained the methionine, or "met," variant and those without the variant.

Previous research has linked the "met" variant with increased risk of depression, stroke, anorexia nervosa, anxiety-related disorders, schizophrenia and suicidal behavior.

The flight simulator test scores of pilots in both groups fell over the three-year study period, but the rate of decline in the "met" group was much steeper, said the researchers at the Stanford University School of Medicine and the Veterans Affairs Palo Alto Health Care System.

"We saw a doubling of the rate of decline in performance on the exam among met carriers during the first two years of follow-up," study senior author Dr. Ahmad Salehi, a clinical associate professor of psychiatry and behavioral sciences at Stanford, said in a university news release.

Using MRI scans, the researchers also found that pilots with the "met" variant showed significant age-rela
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. Morning UV exposure may be less damaging to the skin
2. Congress alert: EUROECHO and Other Imaging Modalities: New patient emphasis
3. Trio of studies support use of PET/CT scans as prostate cancer staging tool
4. Thomas Jefferson University Hospital adopts new imaging agent to improve detection of bladder cancer
5. Relationships more important than genetic ties when deciding who cares for aging family, study finds
6. Staying Sharp in New Haven: Yale brain experts discuss successful aging at free forum
7. Project leads next decade of aging research across Europe
8. Muscling toward a longer life: Genetic aging pathway identified in flies
9. Protein family key to aging, cancer
10. New provincial atlas; information on lab testing key to managing diabetes among Albertans
11. Innovation at Regenstrief: Leveraging novel ideas to improve health care
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Aging Brain's Decline May Hinge on a Gene
(Date:7/24/2014)... (PRWEB) July 24, 2014 Members of the ... Wolnerman, RPh, CCIM, Senior Associate of Sales at OutcomesMTM, as ... appointed him to the Board and that his peers chose ... want to provide the best I can for the citizens ... am uniquely positioned to provide a special insight to concerns ...
(Date:7/24/2014)... that it is possible to predict long-term cancer risk from ... same exposure. The findings, which currently appear in the journal ... simpler and cheaper tests to screen chemicals for their potential ... in incidence of and mortality from cancer, about 40 percent ... lifetime, and around 20 percent will die of it. Currently ...
(Date:7/24/2014)... PHILADELPHAA rare procedure occasionally performed during Jewish circumcisions that ... herpes simplex virus type 1 (HSV-1) transmissions documented ... review conducted by Penn Medicine researchers and published ... Disease Society found. The reviewers, from Penn,s ... cases in New York, Canada and Israel. , The ...
(Date:7/24/2014)... who received the Human Papillomavirus Vaccination (HPV) even ... abnormal Pap test results than those who were ... Sexually Transmitted Diseases . , Researchers ... School of Medicine conducted a cross-sectional study of ... cervical cytology testing. HPV status and demographic and ...
(Date:7/24/2014)... According to market research report "3D Mapping Market: ... Analysis - 2018", the 3D mapping and 3D ... by 2018 at a CAGR of 47.9% by ... and 30 figures spread through 222 pages and ... Business Models, Technology Roadmap, Forecasts and Analysis - ...
Breaking Medicine News(10 mins):Health News:Wolnerman Re-elected as Chairperson of Iowa State Board of Health 2Health News:Researchers discover new way to determine cancer risk of chemicals 2Health News:Link between ritual circumcision procedure and herpes infection in infants examined 2Health News:3D Mapping & 3D Modeling Market Projected to $7.7 Billion by 2018 - Report by MarketsandMarkets 2Health News:3D Mapping & 3D Modeling Market Projected to $7.7 Billion by 2018 - Report by MarketsandMarkets 3Health News:3D Mapping & 3D Modeling Market Projected to $7.7 Billion by 2018 - Report by MarketsandMarkets 4
... Migraine sufferers who experienced abuse and neglect ... disease including stroke and myocardial infarction (MI) among others, ... Society,s 52nd Annual Scientific Meeting in Los Angeles this ... than 1,300 headache clinic patients diagnosed with migraine, investigators ...
... 23, 2010) Typically, migraine is considered to be ... But new research by Dr. Till Sprenger and his ... found increased network activity -- stronger functional connectivity -- ... migraineurs. "There has been increasing evidence ...
... New York, NY, June 23, 2010Despite having the most ... overall compared to six other industrialized countriesAustralia, Canada, Germany, ... of health system performance in five areas: quality, efficiency, ... long, healthy, productive lives, according to a new Commonwealth ...
... 2009 release of guidelines that would have reduced use ... highlights challenges for implementing the findings of comparative effectiveness ... challenges which may become more common due to ... the public and stakeholders about evidence and its connection ...
... Jacksonville ... to college freshman in Florida , ... Orlando, Fla. (June 23, 2010) – "Get tested. Get tested. Get ... to families at his first-ever Playmaker 11 Scholarship ceremony hosted by him on June ...
... to stricter standards, experts suggest , TUESDAY, June 22 ... what is currently considered a normal range for thyroid ... face an increased risk for miscarriage as a result, ... to link what has previously been considered normal thyroid ...
Cached Medicine News:Health News:Migraine sufferers who experienced childhood abuse have greater risk of cardiovascular disease 2Health News:US ranks last among 7 countries on health system performance 2Health News:US ranks last among 7 countries on health system performance 3Health News:Implementing comparative effectiveness research: Lessons from the mammography screening controversy 2Health News:NFL Wide Receiver Mike Sims-Walker Remembers His Father by Giving Out Scholarships 2Health News:Thyroid Function at High End of Normal Tied to Miscarriage Risk 2
(Date:7/24/2014)... MENLO PARK, Calif. , July 24, 2014 ... "the company") announced today that the company,s board of directors ... 31 to June 30. Accordingly, DelMar will file a Transition ... Jeffrey Bacha , president and CEO of DelMar stated, ... in achieving our goal of obtaining a senior exchange listing ...
(Date:7/24/2014)... 2014 LSI Medience Corporation today announced ... Kineticos, a Raleigh-Durham, NC ... LSI Medience in identifying opportunities for Presepsin, a ... in clinical trials. The Presepsin biomarker ... of sepsis, prognosis of septic patients, early risk ...
(Date:7/24/2014)... Talyst, a market leader in pharmacy automation, ... State Veterans Homes (NASVH) Summer Conference in ... NASVH is to ensure that each and every eligible ... care and respect which they have earned by their ... Remote Dispensing System, Talyst can help State Veterans Homes ...
Breaking Medicine Technology:DelMar Pharmaceuticals Announces Change of Fiscal Year End and Provides Update on Glioblastoma Clinical Trial 2DelMar Pharmaceuticals Announces Change of Fiscal Year End and Provides Update on Glioblastoma Clinical Trial 3LSI Medience Corporation and Kineticos Sign Agreement Related to the Presepsin Biomarker in Sepsis Management and Treatment 2Talyst Exhibits at the National Association of State Veterans Homes Summer Conference 2
... 8, 2010 /PRNewswire-Asia-FirstCall/ -- Tianyin Pharmaceutical Co., Inc., ... company that develops, manufactures and sells patented biopharmaceutical, ... pharmaceuticals, today announced that the senior management will ... quarter of fiscal year 2011 ending September 30, ...
... Md., Nov. 8, 2010 Substandard and counterfeit versions ... locations across Ghana by the Medicines Quality Monitoring surveillance ... Board (FDB) in collaboration with the U.S. Pharmacopeial Convention ... the program samples antimalarials across the public and private ...
Cached Medicine Technology:Tianyin Pharmaceutical Co., Inc. to Host First Quarter of Fiscal Year 2011 Earnings Conference Call on Thursday, November 11, 2010 at 9:00 a.m. ET 2Substandard and Counterfeit Antimalarial Drugs in Ghana Discovered by Cooperative Program of USP, Ghana Food and Drugs Board 2Substandard and Counterfeit Antimalarial Drugs in Ghana Discovered by Cooperative Program of USP, Ghana Food and Drugs Board 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: