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Age-related memory loss tied to slip in filtering information quickly
Date:9/2/2008

urochemicals acting on the cells. They also know that there are changes in the neural connections between neurons in far flung parts of the brain.

In the healthy aging brain, these changes are subtle. In the brains of those with mild cognitive impairment and the more severe form of impairment, such as Alzheimer's disease, they are substantial.

The team is now trying to relate how these changes might affect changes in inhibition and processing speed.

They also are investigating strategies for remediating these changes, both mental training exercises that would improve the speed and efficiency of information processing and drugs that would inhibit the brain's attention to extraneous information.

"People's expectations for their later years have changed," says Gazzaley. "They want to remain actively engaged to continue to work, to learn new languages, to move to countries where they can practice their new language.

"The ability to selectively focus our attention, suppress distracting input and hold relevant information in our mind defines our conscious experience and serves as a critical crossroad between attention and memory. The people in our study are functioning well; many are still working, but they want to function at the level they did previously."


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Contact: Jennifer O'Brien
jobrien@pubaff.ucsf.edu
415-476-2557
University of California - San Francisco
Source:Eurekalert

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