Navigation Links
Age and BMI can predict likelihood of developing gestational diabetes new research suggests

Age and body mass index (BMI)are important risk factors for gestational diabetes mellitus (GDM) particularly amongst South Asian and Black African women finds new research published today (02 November) in BJOG: An International Journal of Obstetrics and Gynaecology.

The study looked at the link between maternal age, BMI and racial origin with the development of GDM and how they interact with each other.

Data were collected on 585,291 pregnancies in women attending for antenatal care and delivery at 15 maternity units in North West London from 1988-2000.The study included 1,688 women who developed GDM and 172,632 who did not.

Maternal age was divided into the following groups: below 20, 20-24, 25-29, 30-34, 35-39 and above 40 years of age.

Maternal BMI was also divided according to the WHO international classification of BMI as follows: less than 18.5(underweight), 18.50-24.99 (normal weight), 25.00-29.99 (overweight) and more or equal to 30.00 (obese). Prevalence of GDM was calculated for each maternal age and BMI group.

There was a strong association between GDM development and advancing maternal age which varied by racial group.

Using White European women age 20-24 years as a comparison group, White European women older than 30 years had significantly higher odds ratios (ORs)for developing GDM.

The ORs for GDM development were also significantly higher in the other racial groups but at a younger maternal age (older than 25 years if they were Black Africans or Black Caribbeans and older than 20 years if they were South Asians). Moreover, the rate of GDM rose more rapidly with age. For example, in mothers aged 40 years or more, the rate of GDM had risen to 1.9% in white European mothers (from 0.5% at age 20-24), but to 11.4% in South Asians (from 1.1) and 21.7% in black Africans (from 0.7%).

White European women under the age of 20 were the only group to have significantly lower ORs for developing GDM.

In addition, there was also a strong link between GDM and BMI in all the racial groups. Using White European women with a normal BMI as the comparison group, the ORs for developing GDM were significantly higher in the overweight and obese White European and Black Caribbean groups and significantly higher in all BMI categories of Black African and South Asian women.

Dr Makrina Savvidou, Consultant in Obstetrics and Fetal Medicine, Academic Department of Obstetrics and Gynaecology, Chelsea and Westminster Hospital and co-author of the paper said:

"Gestational diabetes complicates 3-5% of pregnancies. Currently in the UK, the National Institute for Health and Clinical Excellence recommends a diagnostic test for gestational diabetes in women with traditional risk factors, such as increased body mass index, family or previous personal history of gestational diabetes, delivery of a large baby and racial origin with a high prevalence of diabetes.

"However, this new research shows that maternal age, alone and in correlation with the maternal racial origin, may also be a significant factor contributing to the development of gestational diabetes. Age has not been included as one of the screening criteria because the secular increase in maternal age over recent years would have resulted in offering a diagnostic test for gestational diabetes to a high proportion of the pregnant population.

"It is important that clinicians are aware of all the contributing factors as gestational diabetes can result in adverse perinatal outcomes."

Mike Marsh, Deputy Editor-in-Chief of BJOG added:

"It is crucial that women are aware of the benefits of healthy eating and weight control prior to pregnancy as this may reduce the risk of them developing diabetes in pregnancy. Avoiding being overweight prior to pregnancy is particularly important for older women of South Asian and Black African racial origin."


Contact: Naomi Watson

Related medicine news :

1. Research makes it possible to predict how cancers will respond to chemo
2. Blood proteins predict survival in idiopathic pulmonary fibrosis, Pitt-led team says
3. Will my breast cancer spread? Discovery may predict probability of metastasis
4. Mayo Clinic study: PSA test valuable in predicting biopsy need, low-risk prostate cancer
5. Combination of available tests helps predict Alzheimers disease risk
6. New aggression tool predicted violent patients in medical and surgical wards
7. Undergrads Drinking Patterns May Predict Future Abuse
8. Drug safety, efficacy, and potential new cancer biomarker predicted by NextBio
9. New equation predicts molecular forces in hydrophobic interactions
10. Jonesing for java: Could caffeine use predict risk for cocaine abuse?
11. Sniffing out the brains predictive power
Post Your Comments:
(Date:6/26/2016)... Charlotte, NC (PRWEB) , ... June 26, 2016 , ... Brent Kasmer, a legally blind ... able to be personalized through a fitness app. The fitness app plans to fix the ... solutions currently only offer a one size fits all type program , They ...
(Date:6/25/2016)... ... June 25, 2016 , ... Austin residents seeking Mohs surgery ... of Mohs Surgery and to Dr. Russell Peckham for medical and surgical dermatology. , ... for skin cancer. The selective fellowship in Mohs Micrographic Surgery completed by Dr. Dorsey ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... First ... United States, named Dr. Sesan Ogunleye, as the Medical Director of its new Mesquite-Samuell ... facility Medical Director of our new Mesquite location,” said Dr. James M. Muzzarelli, Executive ...
(Date:6/25/2016)... (PRWEB) , ... June 25, 2016 , ... On Friday, ... presented a Bronze Wellness at Work award to iHire in recognition of their exemplary ... part of the 7th annual Maryland Workplace Health & Wellness Symposium at the BWI ...
(Date:6/24/2016)... Michigan (PRWEB) , ... June 24, 2016 , ... Those ... deal with these feelings, many turn to unhealthy avenues, such as drug or alcohol ... of Marne, Michigan, has released tools for healthy coping following a traumatic event. , ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)...  VMS Rehab Systems, Inc. ( ) reported ... required to build a strong and stable market for ... on the OTC Markets-pink current trading platform. ... are seeing an anomaly in market trading activities that ... the Company, but shareholders and market players as well. ...
(Date:6/24/2016)... , June 24, 2016  Global Blood Therapeutics, ... company developing novel therapeutics for the treatment of ... announced the closing of its previously announced underwritten ... at the public offering price of $18.75 per ... were offered by GBT. GBT estimates net proceeds ...
(Date:6/24/2016)... -- The Academy of Managed Care Pharmacy (AMCP) today ... allow biopharmaceutical companies to more easily share health care ... coverage decisions, a move that addresses the growing need ... The recommendations address restrictions in the sharing of product ... a prohibition that hinders decision makers from accessing HCEI ...
Breaking Medicine Technology: