Navigation Links
Age, Race May Affect Type 2 Diabetes Screening Results
Date:6/21/2010

The recommended A1c blood test cutoff didn't accurately diagnose elderly Asians, study found

MONDAY, June 21 (HealthDay News) -- Despite its endorsement last year by the American Diabetes Association as an effective way to diagnose type 2 diabetes, new research out of Singapore suggests that the hemoglobin A1c blood test may not accurately identify the disease among elderly Asians.

The American Diabetes Association's current recommendation is that this particular test -- not previously considered to be a gold standard screening method -- works well when physicians rely on a cutoff reading of 6.5 percent or more to indicate diabetes.

Yet, the new study found that, among a group of Asian participants ranging in age from 20 to 93 years, the 6.5 percent cutoff misses many instances of disease, and may lead to under-diagnosis of diabetes with increasing frequency as Asian patients get older.

"The hemoglobin A1c is a useful and convenient screening test for diabetes," Dr. Tunn Lin Tay, an endocrinology fellow at Singapore's Changi General Hospital, said in a news release from The Endocrine Society. "However, we may need age-specific reference ranges, rather than using a single cutoff level across the board."

The findings were to be presented Sunday at the Endocrine Society's annual meeting in San Diego.

Although A1c has long been used to monitor a diabetic's long-term blood sugar levels, the authors noted that the standard means for screening for the disease has been either the fasting plasma glucose test or, ideally, the oral glucose tolerance test.

The A1c test, however, does not require eight hours of pre-exam fasting, and is considered simpler and less time-consuming than the two-hour long glucose tolerance test.

But to see how A1c stacked up against the glucose tolerance test, Tay's team used both methods to screen 90 primarily Chinese patients with no previous history of diabetes.

The standard oral glucose test discovered 40 cases of type 2 diabetes, the researchers found. On the other hand, the A1c test was less and less accurate as the patients' ages rose, only diagnosing about 55 percent of the cases among participants over the age of 72.

Among such elderly Asian patients, 6 percent is the best cutoff point, the authors said. And among patients under 72 years of age, 6.2 percent may be best.

"If clinicians screen elderly patients -- especially Asians -- using the hemoglobin A1c test, they should confirm the diagnosis using the oral glucose tolerance test," Tay stated in the news release.

More information

The American Diabetes Association has details about type 2 diabetes.



-- Alan Mozes



SOURCE: The Endocrine Society, news release, June 20, 2010


'/>"/>
Copyright©2010 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Mechanical forces could affect gene expression
2. Kool Smiles Offers Free Toothbrushes and Education to Day Care Centers Affected by Massachusetts Initiative Supporting Childrens Oral Care
3. Anesthetic approach stops pain without affecting motor function
4. Anesthetic Approach Stops Pain Without Affecting Motor Function
5. Mount Sinai finds prenatal exposure to certain chemicals affects childhood neurodevelopment
6. Alcohol Affects Babys Pain Regulation
7. A novel computational model -- how Parkinsons medications affect learning and attention
8. Even Mild Lung Disease Affects the Heart
9. Prenatal exposure to flame-retardant compounds affects neurodevelopment of young children
10. People affected by autism believe increase is real, not diagnostic
11. Hardship in Childhood May Affect Long-Term Health
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Age, Race May Affect Type 2 Diabetes Screening Results
(Date:3/24/2017)... , ... March 24, 2017 , ... “End Time GPS”: ... salient events will interrelate. “End Time GPS” is the creation of published author, ... expert while working on military munitions and space-vehicle projects. Now, at age ninety-one, he ...
(Date:3/24/2017)... ... March 24, 2017 , ... “The Communion ... real people of God in congregations across the United States. “The Communion ... ordained in 1964 who has served congregations in seven states throughout his long ...
(Date:3/23/2017)... ... 23, 2017 , ... In 2016 the World Health Organization declared the Zika ... million Zika-related cases in the Americas within the next year. Lyme disease is one ... year skyrocketing to an estimated 329,000. Yet, Zika, Lyme and other insect borne illnesses ...
(Date:3/23/2017)... ... March 23, 2017 , ... The physicians of KSF Orthopaedic ... greater Houston Area. The new location is located at 2255 E. Mossy Oaks Rd., ... Village. This newest location will provide patients living in the north Houston area (The ...
(Date:3/23/2017)... ... March 23, 2017 , ... Texas Physical Therapy Specialists (TexPTS) ... Road in Building 2. The clinic is the group’s second in New Braunfels and ... the company’s second New Braunfels location brings things full circle for the group, “It’s ...
Breaking Medicine News(10 mins):
(Date:3/24/2017)... India , March 24, 2017 ... of the industry including definitions, classifications, applications and industry ... the international market including development history, competitive landscape analysis, ... ... Ampoules industry spread across 105 pages providing 10 company ...
(Date:3/24/2017)... SAN DIEGO , March 24, 2017  GenomeDx ... (Genomics Resource Information Database) and Decipher® Prostate Cancer Classifier ... Annual European Association of Urology (EAU) Congress held March ... . The Annual EAU Congress is ... and most comprehensive research in the urological field. ...
(Date:3/24/2017)...  Mirabilis Medical, a Seattle ... surgery, announced today CE Mark authorization for marketing ... fibroids throughout the European Union.  The company simultaneously ... US Food and Drug Administration to begin a ... United States.  The Mirabilis System combines high-speed therapeutic ...
Breaking Medicine Technology: