Navigation Links
African-Americans with colorectal cancer have poorer outcomes, lower survival rates
Date:11/12/2009

CHICAGO (November 12, 2009) New research published in the November issue of the Journal of the American College of Surgeons shows that African-American patients with colorectal cancer are more likely to be diagnosed with advanced disease and are less likely to undergo surgical procedures compared with Caucasians, suggesting that improvements in screening and rates of operation may reduce differences in colorectal cancer outcomes for African-Americans.

Racial disparities previously have been demonstrated in numerous studies for a number of cancers, typically due to unequal access to care. As a result, the identification and elimination of these disparities has become a national public health priority.

"Colorectal cancer is the only gastrointestinal cancer that is routinely screened for and can be effectively treated, yet African-Americans still have a profoundly lower survival rate than Caucasians," said Timothy L. Fitzgerald, MD, FACS, associate professor, department of surgery, division of surgical oncology, East Carolina University in Greenville, NC. "Our analysis suggests that these disparities may be attributable to a lack of access to or use of care. It is imperative that screening and treatment are delivered equally to all patients."

East Carolina researchers used four years of population-based Medicare and Medicaid administrative claims merged with the Michigan Tumor Registry and identified data for 18,260 patients (≥66 years) with colorectal (n=13,001; 11.31 percent African-American), pancreatic (n=2,427; 14.38 percent African-American), gastric (n=1,739; 17.49 percent African-American) and esophageal (n=1,093; 13.50 percent African-American) cancer. Key data used in the analysis included likelihood of late-stage diagnosis, likelihood of surgical treatment after diagnosis, and survival.

In evaluating an unadjusted analyses, researchers discovered that African-American patients with colorectal cancer were more likely to present with metastatic disease (23.17 percent versus 14.75 percent Caucasians; p<0.05) and less likely to undergo operations (71.25 percent versus 79.05 percent; p<0.05), regardless of socioeconomic factors. This finding was the case even when the analysis was confined to patients with localized, surgically treatable diseases.

The median survival of African-Americans with colorectal cancer (39 months versus 56 months) and esophageal cancer (5 months versus 9 months) in the study was significantly less than that for Caucasians (p < 0.05). Survival was similarly poor for pancreatic and gastric cancer patients regardless of race.

In conducting a multivariate analysis, the research team found that African-American patients had a higher likelihood of dying from colorectal cancer than Caucasian patients did. However, this difference did not persist when adjustments were made for disease stage and presence or absence of a surgical procedure (hazard ratio = 1.15, 95% CI = 1.06 1.24). There was no association between survival and race for patients with esophagus, gastric or pancreatic cancer. Other variables of interest and statistical significance were median household income below $35,000, a dual eligibility insurance status and older age, all of which were negatively associated with colorectal cancer survival.


'/>"/>

Contact: Sally Garneski
pressinquiry@facs.org
312-202-5409
Weber Shandwick Worldwide
Source:Eurekalert

Related medicine news :

1. Grammy(R)-Nominated R&B Sensation Angie Stone Teams up With the American Diabetes Association to Encourage African-Americans to be Victorious in the Face of Diabetes
2. HPV infection may be linked to poor head and neck cancer survival rates in African-Americans
3. Study finds survival rates from gastrointestinal tumors improving among African-Americans
4. Why African-Americans are at greater risk of hypertension and kidney disease
5. What is different in reflux esophagitis between African-Americans and non-Hispanic whites?
6. Grammy-nominated Singer Angie Stone Encourages African-Americans in Birmingham to Fearlessly FACE Diabetes
7. Hormone linked to high blood pressure and blood vessel disease in African-Americans
8. Childrens Hospital study finds African-Americans more distrusting of research than whites
9. African-Americans have worse prognosis at colorectal cancer diagnosis
10. Fear, misconceptions about screenings keep many African-Americans from getting mammograms
11. MYH9 gene variations help explain high rate of kidney disease in African-Americans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/23/2017)... Va. (PRWEB) , ... June 23, 2017 , ... The ... the president's nominee for deputy secretary of Veterans Affairs, retired Marine Col. Thomas G. ... Veterans Affairs. , Bowman brings an intimacy with the issues and challenges ...
(Date:6/23/2017)... (PRWEB) , ... June 23, 2017 , ... Everybody has ... it while others prefer to read it, and some people don't like it at ... pornography. Here's what they found: , Erotic literature can give readers a taste of ...
(Date:6/23/2017)... ... June 23, 2017 , ... Ensuring meat products have reached ... the importance of correctly using a meat thermometer. The videos feature University of ... on consumer food safety habits. Dr. Bruhn explains the variety of meat thermometers ...
(Date:6/23/2017)... (PRWEB) , ... June 23, 2017 , ... MD ... Florida. This is MD Now’s 28th facility overall and marks the urgent care center's ... located one mile North of The Falls shopping mall. The new clinic offers a ...
(Date:6/23/2017)... ... June 23, 2017 , ... American Farmer, will feature Chr. ... is slated to air fourth quarter 2017. American Farmer airs Tuesdays at 8:30aET on ... Danish pharmacist, founded Chr. Hansen in Denmark in 1874 after a groundbreaking discovery of ...
Breaking Medicine News(10 mins):
(Date:6/19/2017)... June 19, 2017  Researchers from DRUGSCAN ® ... will host a live, complimentary webinar titled, "Untangling methods ... to the real world" on Wednesday June 28, 2017 ... This webinar will feature interviews with recreational and ... the manipulation techniques abusers use to prepare opioid tablets ...
(Date:6/14/2017)... -- In 2016, Embodied Labs took top prize ... came away with $25,000 in seed-fund investment. Embodied Labs ... "entering the life of another" and by the Journal ... medical professionals in an entirely new dimension." Building upon ... for the Department of Education,s EdSimChallenge, where they received ...
(Date:6/9/2017)... AirXpanders, Inc. (ASX: AXP) (AirXpanders or Company), ... sale and distribution of the AeroForm® Tissue Expander System, ... commercial roll-out in the United States ... hundred (100) medical institutions and health systems, located throughout ... alternative for women who choose reconstructive surgery following a ...
Breaking Medicine Technology: