Navigation Links
African-American women with advanced breast cancer often forego vital treatment
Date:5/21/2009

A new study finds that nearly one in four African American women with late stage breast cancer refused chemotherapy and radiation therapy, potentially life saving therapies. Published in the July 1, 2009 issue of CANCER, a peer-reviewed journal of the American Cancer Society, the study indicates that more efforts are needed to ensure that all women with breast cancer receive appropriate care.

In the United States, African American women have almost twice the rate of advanced (stage III) breast cancer than white women. To get a better sense of the tumor characteristics and medical care of these patients, researchers led by Monica Rizzo, M.D., of the Emory University School of Medicine and Emory University's Avon Comprehensive Breast Cancer Center at Grady reviewed stage III breast cancer data from 2000 to 2006 from an inner city hospital in Atlanta that serves a large African American population.

The investigators identified 107 cases of stage III breast cancers diagnosed and/or treated at this hospital over the six years of study. Approximately 87 percent of these cases were in African American women. Triple negative tumors accounted for 29 percent of the cases. These cancers do not express the estrogen receptor, the progesterone receptor or the human epidermal growth factor receptor 2 (HER2) and therefore do not respond well to therapies that target these proteins (such as trastuzumab, or Herceptin, which blocks HER2).

Chemotherapy and radiation are recommended therapies for patients with stage III breast cancer; however many women in this study decided to forego these treatments. The study found 20.5 percent of patients with stage III breast cancer refused chemotherapy, and 26.3 percent who should have received chest radiation refused. There was no difference in marital status, religious background, or age of the patients who refused either chemotherapy or radiation compared with the patients who received recommended care.

The authors say the reasons why African American women with advanced breast cancer often refuse necessary care are unclear. They could include socioeconomic and demographic factors, cultural beliefs, healthcare access, additional illnesses, and patient choice. Additional studies are needed to better define which factors play a role.

To dispel fears of cancer treatment and encourage compliance with recommended therapies, the study investigators have implemented a community outreach program at their institution. The program includes a nurse practitioner and a social worker who carefully follow all patients during and after their cancer treatments. "The high rate of refusal for important life saving therapies that we identified needs further study after implementation of our planned initiatives, so all women are offered and will receive appropriate care based on stage of diagnosis," the authors wrote.


'/>"/>

Contact: David Sampson
david.sampson@cancer.org
American Cancer Society
Source:Eurekalert

Related medicine news :

1. African-American women still have poorer breast cancer outcomes
2. High blood pressure linked to earlier death among African-American breast cancer patients
3. PSA levels accurately predict prostate cancer risk in African-American men
4. Grammy-nominated Singer Angie Stone Encourages African-Americans in Birmingham to Fearlessly FACE Diabetes
5. Hormone linked to high blood pressure and blood vessel disease in African-Americans
6. Childrens Hospital study finds African-Americans more distrusting of research than whites
7. African-Americans have worse prognosis at colorectal cancer diagnosis
8. Outdoor alcohol advertising and problem drinking among African-American women in NYC
9. Gay and bisexual African-American men have the lowest use of prostate testing
10. Birthing Project USA Unites to Reduce the African-American Infant Mortality Rate: Pilgrimage to Babyland
11. Church effort sharply increases first-time African-American blood donors
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/28/2016)... ... ... May 26, 2016- In search of the K. Warriors, Shaolin Institute is ... Warriors” on June 4, 2016 at Ashbury Hotel and Suites 600 West Interstate 65 ... by Shaolin Institute and sanctioned by KSF (Kungfu Sanda Federation), This is the 28th ...
(Date:5/27/2016)... ... May 27, 2016 , ... Two director-level employees of Horizon ... to Women and Industry (TWIN) 2016 honorees. The award recognizes businesswomen who excel ... year, Geri Boone, Director of the MLTSS (Managed Long-Term Services and Supports) Program at ...
(Date:5/27/2016)... ... 27, 2016 , ... An educational campaign aimed at everyone ... courtesy of awareness-driven celebrities and thought leaders. It also provides insight to the ... leaders such as Bioness. , As patients feel increasingly concerned about the ...
(Date:5/27/2016)... (PRWEB) , ... May 27, 2016 , ... ... in scholarships to students studying complementary medicine. Allison Outerbridge is this year’s ... her award on May 18 at the university’s Student Leadership Awards ceremony. , ...
(Date:5/26/2016)... ... May 26, 2016 , ... ... thousands of defective respirators, according to court documents and SEC filings. A ... and Becky Tyler v. American Optical Corporation, Case No. BC588866, Los Angeles County, ...
Breaking Medicine News(10 mins):
(Date:5/27/2016)... 27, 2016 Kitov ... focused on late-stage drug development, today announced the ... of pivotal batches required for registration of KIT-302 ... This follows Kitov,s announcement in December ... met its primary efficacy endpoint. "We ...
(Date:5/26/2016)... A key trend that will ... of new treatments. Cardax, a development stage life sciences ... therapy is expected to fulfil large unmet medical needs ... studies to develop new treatments for osteoarthritis. One such ... in osteoarthritis are being investigated, and early trials of ...
(Date:5/25/2016)... , May 25,2016 ... the near-infrared Cellvizio platform for urological and surgical ... OTCQX: MKEAY) inventor of Cellvizio®, the multidisciplinary confocal ... regulatory milestone in the US with the 12 ... and Drug Administration (FDA). This new FDA clearance ...
Breaking Medicine Technology: