Navigation Links
African American women with HIV/HCV less likely to die from liver disease
Date:11/1/2012

A new study shows that African American women coinfected with human immunodeficiency virus (HIV) and hepatitis C virus (HCV) are less likely to die from liver disease than Caucasian or Hispanic women. Findings in the November issue of Hepatology, a journal published by Wiley on behalf of the American Association for the Study of Liver Diseases, indicate that lower liver-related mortality in African American women was independent of other causes of death.

Medical evidence reports that nearly five million Americans are infected with HCV, with 80% having active virus in their blood (viremia). Moreover, prior research found that one third of those with HIV are co-infected with HCVthe second leading cause of death among those with HIV. Studies also show that while HCV clearance (elimination of the virus spontaneously or with treatment) is lower among African Americans, once chronically infected this group seems to develop less fibrosis and liver inflammation compared to other racial groups.

"Despite much study on racial differences in hepatitis C development, it remains unclear how race impacts liver-related death in those with HCV or HIV/HCV co-infection," said Dr. Monika Sarkar from the University of California, San Francisco and lead author of the current study examining racial differences and mortality among women with HIV and HCV.

The UCSF team followed 794 subjects who were part of the Women's Interagency HIV study, which was funded by the National Institutes of Health (NIH). Those women in the follow-up study included 140 Caucasians (62%), 159 Hispanics (20%), and 495 African Americans (18%). Study participants were seen twice each year to have detailed health histories, physical exams, interviews, and clinical testing.

During a median follow-up of nearly 9 years, researchers documented 438 deaths; 37% from HIV/AIDS and 11% due to liver-related disease. Nearly 56% of African Americans, 56% of Caucasians and 52% of Hispanics died during follow-up. The team reports that liver disease was the primary cause of death in 21% of Hispanics, 14% of Caucasians, and only 8% of African Americans.

"Our findings indicate that the number of African American women co-infected with HIV/HCV who died from liver disease was significantly lower than Caucasian and Hispanic women with the same diseases," concludes Dr. Sarkar. "Further studies are needed to understand the reasons for such a discrepancy in liver-related mortality among these racial groups."


'/>"/>

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert

Related medicine news :

1. Blood pressure diet works, but adherence drops among African-Americans
2. Religions play positive role in African AIDS crisis
3. Genetic link to prostate cancer risk in African Americans found
4. New genetic risk factor for inflammation identified in African-American women
5. African Chimps Carry Drug-Resistant, Human-Linked Staph
6. UCLA-led project aimed at African American couples affected by HIV gets $2.5 million boost
7. HPV improves survival for African-Americans with throat cancer
8. Tobacco use more prevalent among African-American adolescents living in public housing communities
9. Johns Hopkins African bioethics program receives 5-year continuation grant from NIH
10. Stanford researchers discover the African cichlids noisy courtship ritual
11. Study finds socioeconomic status linked to weight gain and risk of obesity in African-American women
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/20/2017)... ... 2017 , ... Recognising that in today’s busy world consumers ... positive results in just three weeks. Setting the groundwork for a healthier lifestyle, ... into hectic work and family schedules, participants can lose up to 15lbs during ...
(Date:9/20/2017)... ... September 20, 2017 , ... Ron Norman, CEO ... marketers this week about the value of senior executives, pointed to a quote ... in business has brought us to the present and will lead us into ...
(Date:9/20/2017)... ... ... “Monique”: is the story of Monique, whose mother’s deteriorating physical condition forces the ... has owned four beauty salons and written a book regarding the author’s success in ... , “The doctor’s office was only three blocks away, and she could walk it, ...
(Date:9/19/2017)... ... September 19, 2017 , ... Trusted debt-reduction firm CreditAssociates, LLC has ... translating to in excess of $835 million in resolved debt for its clients. , ... are some of the categories of debt settled by the company. With more than ...
(Date:9/19/2017)... ... September 19, 2017 , ... The ... Canyon Ranch to its recently formed Corporate Roundtable, a group of individuals ... and a sustainable world. , Canyon Ranch is a unique collection of lifestyle-based ...
Breaking Medicine News(10 mins):
(Date:9/18/2017)... Sept. 18, 2017 EpiVax, Inc. ... bioinformatics and immune engineering, today announced a ... A (H7N9) vaccine. ... seasonal influenza and presents a challenge for ... exposure to be effective. Using state-of-the-art bioinformatics and ...
(Date:9/9/2017)... WASHINGTON , Sept. 8, 2017 ... Mobile MRI Unit coming to Washington DC ... When: Tuesday, September 12 th – Monday, ... to Washington, D.C. offering free MRI brain scans to the public.Where:  ... – will be parked at 501 K Street NW, Washington, D.C.What:BTF brings ...
(Date:9/7/2017)... Texas , Sept. 7, 2017 ... science focused on fulfilling the promise of precision ... further validate the benefits of its molecular profiling ... study utilized comprehensive genomic profiling plus (CGP+) with ... individual patient,s tumor on a molecular level, leading ...
Breaking Medicine Technology: