Navigation Links
African-American women more likely to be diagnosed with higher risk breast cancer
Date:6/9/2014

Washington, D.C., June 9, 2014 - A research study led by cancer specialists at MedStar Washington Hospital Center found that African-American women frequently present with biologically less favorable subtypes of breast cancer.

Researchers at the Hospital Center's Washington Cancer Institute analyzed the biology of breast cancer in 100 African-American women, using a method of genomic profiling. These genomic tests look at the expression of genes associated with the risk of recurrence in the population and further characterizes the biology of the tumor. The 70-gene MammaPrint test was used to determine the likelihood of a cancer recurrence. Out of the 100 patients, 66 women in the study were found to be high risk, meaning that their tumors had a higher risk of recurrence.

A companion BluePrint test was used to define the specific molecular subtype of each cancer. When classified by both genomic tests, African- American women with stage I to III breast cancer often presented with gene expression subtypes that were less favorable. The co-author of the research, Raquel Nunes, MD, a medical oncologist at the Washington Cancer Institute, presented the data as a scientific poster at the recent American Society of Clinical Oncology annual meeting.

"It's important that research continues to address these issues comprehensively, from the biology of the disease to the development of optimal treatment and access to healthcare." said Dr. Nunes. "This work is particularly meaningful for us because it complements our interest in health disparities and highlights the enthusiastic participation of African-Americans in breast cancer research."

Unlike genetic tests such as those for BRCA genes (which are inherited and look at overall susceptibility for developing breast cancer), genomic tests look at the genes inside a breast cancer cell and how strongly they are expressed. The findings support prior research that has looked at the biologic characteristics of breast cancer in African-American women, but this specific methodology reported here was used for the first time in this population.

Cancer specialists will continue to follow the patients in the research study over the next five years to evaluate their survival with treatment, according to their gene profile.


'/>"/>

Contact: Sylvia T. Ballinger
sylvia.t.ballinger@gmail.com
202-877-7072
MedStar Washington Hospital Center
Source:Eurekalert

Related medicine news :

1. Can weight loss help African-American breast cancer survivors?
2. Equal access to care helps close survival gap for young African-American cancer patients
3. WSU study finds overwhelming evidence of hidden heart disease in hypertensive African-Americans
4. Study finds socioeconomic status linked to weight gain and risk of obesity in African-American women
5. Tobacco use more prevalent among African-American adolescents living in public housing communities
6. HPV improves survival for African-Americans with throat cancer
7. New genetic risk factor for inflammation identified in African-American women
8. Blood pressure diet works, but adherence drops among African-Americans
9. Study helps bridge gap in understanding of suicide risk for African-American women
10. Gay African-American youth face unique challenges coming out to families
11. Exercise linked with reduced prostate cancer risk in Caucasians but not African-Americans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/16/2017)... ... August 16, 2017 , ... Any Lab Test Now® ... company ranked #4429 on the newly released, 36th annual Inc. 5000 , the ... look at the most successful companies within the American economy’s most dynamic segment — ...
(Date:8/16/2017)... ... , ... In a recent survey, eighty-two percent of women reported having cellulite, ... can't always be eliminated by diet and exercise alone, and now for the first ... Dr. Kenneth Rothaus has recently added Cellulaze™ to his practice in New ...
(Date:8/16/2017)... ... August 16, 2017 , ... Maury Regional Health has announced ... draws. By broadly deploying AccuVein devices, Maury Regional Medical Center is making vein visualization ... out of a needle stick and more importantly, helps our staff members locate a ...
(Date:8/16/2017)... Ca (PRWEB) , ... August 16, 2017 , ... ... engineers, and scientists from around the world, is excited to announce Andrew Ly as ... in his academic pursuits, covering textbook costs. , Ly, who is in his ...
(Date:8/16/2017)... ... August 16, 2017 , ... ... the endoscope after every reprocessing cycle, both between patient procedures and before storage, ... infections. Drying is as important to the prevention of disease transmission and nosocomial ...
Breaking Medicine News(10 mins):
(Date:7/28/2017)... 28, 2017 EnvoyHealth, a Diplomat company, has partnered ... for CleverCap LITE, a technology designed to improve patient ... innovative health technology solutions and services that help track ... CleverCap LITE offers medication monitoring and control ... Records date and ...
(Date:7/26/2017)... , July 27, 2017  Radium Medical Aesthetics, a leading medical ... to delay aging by effectively addressing several skin conditions from the ... to become rougher and more fragile. The skin becomes more transparent ... exposure to the harmful UV rays from the sun contributes to ... ...
(Date:7/25/2017)... Curing Stomach Cancer (DDF) is excited to host its 3 rd Annual ... Spa in Weston, Florida beginning at 10:30 a.m.   ... Luncheon Committee Co-chair and DDF Board ... Sabrina Kurzman. ... Aura Morales-Guzman, Angela Perez, DDF Board Member John Nash (of 2016 ...
Breaking Medicine Technology: