Navigation Links
African-American women more likely to be diagnosed with higher risk breast cancer
Date:6/9/2014

Washington, D.C., June 9, 2014 - A research study led by cancer specialists at MedStar Washington Hospital Center found that African-American women frequently present with biologically less favorable subtypes of breast cancer.

Researchers at the Hospital Center's Washington Cancer Institute analyzed the biology of breast cancer in 100 African-American women, using a method of genomic profiling. These genomic tests look at the expression of genes associated with the risk of recurrence in the population and further characterizes the biology of the tumor. The 70-gene MammaPrint test was used to determine the likelihood of a cancer recurrence. Out of the 100 patients, 66 women in the study were found to be high risk, meaning that their tumors had a higher risk of recurrence.

A companion BluePrint test was used to define the specific molecular subtype of each cancer. When classified by both genomic tests, African- American women with stage I to III breast cancer often presented with gene expression subtypes that were less favorable. The co-author of the research, Raquel Nunes, MD, a medical oncologist at the Washington Cancer Institute, presented the data as a scientific poster at the recent American Society of Clinical Oncology annual meeting.

"It's important that research continues to address these issues comprehensively, from the biology of the disease to the development of optimal treatment and access to healthcare." said Dr. Nunes. "This work is particularly meaningful for us because it complements our interest in health disparities and highlights the enthusiastic participation of African-Americans in breast cancer research."

Unlike genetic tests such as those for BRCA genes (which are inherited and look at overall susceptibility for developing breast cancer), genomic tests look at the genes inside a breast cancer cell and how strongly they are expressed. The findings support prior research that has looked at the biologic characteristics of breast cancer in African-American women, but this specific methodology reported here was used for the first time in this population.

Cancer specialists will continue to follow the patients in the research study over the next five years to evaluate their survival with treatment, according to their gene profile.


'/>"/>

Contact: Sylvia T. Ballinger
sylvia.t.ballinger@gmail.com
202-877-7072
MedStar Washington Hospital Center
Source:Eurekalert

Related medicine news :

1. Can weight loss help African-American breast cancer survivors?
2. Equal access to care helps close survival gap for young African-American cancer patients
3. WSU study finds overwhelming evidence of hidden heart disease in hypertensive African-Americans
4. Study finds socioeconomic status linked to weight gain and risk of obesity in African-American women
5. Tobacco use more prevalent among African-American adolescents living in public housing communities
6. HPV improves survival for African-Americans with throat cancer
7. New genetic risk factor for inflammation identified in African-American women
8. Blood pressure diet works, but adherence drops among African-Americans
9. Study helps bridge gap in understanding of suicide risk for African-American women
10. Gay African-American youth face unique challenges coming out to families
11. Exercise linked with reduced prostate cancer risk in Caucasians but not African-Americans
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/10/2016)... ... February 09, 2016 , ... Ross A. Clevens, MD, ... to welcome a new addition to their growing practice. Beginning this month, Teresa ... nurse practitioner performing cosmetic procedures including injectables, fillers and laser treatments. ...
(Date:2/9/2016)... ... February 09, 2016 , ... Steven Douglas Associates is a ... Florida Event, an upscale fundraiser held in South Florida. The Inaugural What’s Your Taste ... This year the event will be held in a new, more causal format at ...
(Date:2/9/2016)... ... February 09, 2016 , ... ... production of its newest mobility device, the StandUp Walker. Made entirely in the ... in the last 50 years. , StandUp Walker’s novel patent-pending design offers 2-in-1 ...
(Date:2/9/2016)... Springs, FL (PRWEB) , ... February 09, 2016 ... ... leading innovative specialty pharmacies, announces today the continuation of the ‘Pay It Forward’ ... for each prescription referral received at our specialty pharmacy. , “Since our ...
(Date:2/9/2016)... ... February 09, 2016 , ... The Bon-Ton Stores, Inc. (NASDAQ: ... stores, announced it has raised $176,000 to benefit the Breast Cancer Research Foundation, ... at the University of Iowa, The Lynn Sage Cancer Research Foundation, and Masonic ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... , Feb. 9, 2016 On ... Administration (FDA) met with its Arthritis Advisory ... biosimilar of Johnson & Johnson,s Remicade and ... approved in the U.S. The Biologics Prescribers ... groups - Alliance for Patient Access, American ...
(Date:2/9/2016)... Calif. , Feb. 9, 2016 /PRNewswire/ - Nevro ... company that is providing innovative evidence-based solutions for the ... release financial results for the fourth quarter and full ... 29, 2016. Company management will host a conference call ... Time) on Monday, February 29, 2016. www.nevro.com ...
(Date:2/9/2016)... 9, 2016  Sangamo BioSciences, Inc. (NASDAQ: ... today reported its fourth quarter and full year ... vivo therapeutic genome editing," said Edward Lanphier, ... finger nuclease (ZFN) technology leads the therapeutic genome ... competencies necessary to move our ground-breaking genome editing ...
Breaking Medicine Technology: