Navigation Links
Aeras and Crucell announce Phase II clinical trial start in Kenya
Date:9/22/2010

Leiden, The Netherlands / Rockville, MD, USA (September 22, 2010) Dutch biopharmaceutical company Crucell N.V. (Euronext, Nasdaq: CRXL; Swiss Exchange: CRX) and the Aeras Global TB Vaccine Foundation today announced the start of a Phase II clinical trial in infants of the jointly developed tuberculosis (TB) vaccine candidate, AERAS-402/Crucell Ad35.

The main objective of the trial is to test the safety and efficacy of the TB vaccine candidate in infants previously vaccinated with the Bacille Calmette-Gurin (BCG) vaccine, which is currently the only vaccine licensed to help prevent TB. The first part of this clinical trial, which will be conducted in Kenya, will establish the optimal dosing regimen. The selected regimen will then be tested in the second part of the trial, which is planned to begin in 2011 in Kenya, Mozambique, South Africa and Uganda.

The Phase II study of AERAS-402/Crucell Ad35 is being led in Kenya by a joint research project of the Kenya Medical Research Institute and the US Centers for Disease Control and Prevention, called the KEMRI/CDC Research and Public Health Collaboration. Participants from the Siaya District in Nyanza Province of Western Kenya will be enrolled.

"Despite the availability of the BCG vaccine, two million men, women and children die from tuberculosis every year. We urgently need a new TB vaccine to ensure long-term and effective TB protection," said Jim Connolly, President and CEO of the Aeras Global TB Vaccine Foundation. "This clinical trial represents an important step in our collaboration among a global network of researchers and the people of Kenya, who continue to be at high-risk for TB infection."

In 2004, Aeras and Crucell began jointly developing this vaccine candidate using Crucell's AdVac vaccine technology and PER.C6 manufacturing technology.

"I am extremely pleased at the pace in which our work to develop a next generation vaccine against TB is progressing. O
'/>"/>

Contact: Annmarie Leadman
aleadman@aeras.org
240-599-3018
Aeras Global TB Vaccine Foundation
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Lincare Holdings Inc. Announces Fourth Quarter and Year Ended 2009 Financial Results
2. CustomerCentric Selling and Kadient Announce Joint Event in Boston to Launch Strategic Partnership for Sales Enablement and Improvement
3. Connecture, Inc. Announces Partnership with MedicareCRM
4. Chiquita Announces Support for School Salad Bar Campaign
5. Team Health Holdings, Inc., Announces Fourth Quarter and Fiscal 2009 Financial Results
6. MDS Announces Agreements to Divest MDS Pharma Services Early Stage Business
7. MyDietShopz.com Announces Biggest Losers Contest - Share Your Story To Inspire Others
8. Rocketboy Media Wins Award for Masonic Lodge Web Site; Announces Signing of Several New Clients
9. Emergency Nurses Association Announces Corporate Sponsors for Leadership Conference
10. Whitemark Homes Inc. Announces Change of Auditors and Additional Corporate Information
11. Sunquest Announces Major Software Updates and Enhancements
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2014)... Oregon State University researcher has found a relationship between ... of autism spectrum disorder in very young children. ... to show a direct relationship between motor skills and ... motor skills should be included in treatment plans for ... professor in OSU,s College of Public Health and Human ...
(Date:4/24/2014)... New research led by a scientist at the University ... key element in the development of the nervous system ... of breast cancer., A research team, led by ... the Department of Biology at York, has studied how ... tumours. These channels are found in the membranes of ...
(Date:4/23/2014)... Pregnant immigrants from Sub-Saharan Africa, Latin America ... pregnancy, according to new research from St. Michael,s ... British Journal of Obstetrics and Gynaecology , ... among immigrants and native-born women in six high-immigration ... Spain (Catalonia and Valencia) and the United States ...
(Date:4/23/2014)... at the National Institute of Arthritis and Musculoskeletal and ... of the Ross Prize in Molecular Medicine, conferred by ... . The award will be given on June 9 ... followed by scientific presentations by Dr. O,Shea and other ... of Health. , The award, which includes a $50,000 ...
(Date:4/23/2014)... that rats exposed to high-energy particles, simulating conditions astronauts ... lapses in attention and slower reaction times, even when ... , The cognitive impairments which affected a large ... appear to be linked to protein changes in the ... hold true in humans, suggest it may be possible ...
Breaking Medicine News(10 mins):Health News:Motor skill deficiencies linked to autism severity in new research 2Health News:Breast cancer replicates brain development process 2Health News:Pregnancy complications may be more common in immigrants from certain regions 2Health News:NIH scientist to receive Ross Prize in Molecular Medicine 2Health News:Some astronauts at risk for cognitive impairment, animal studies suggest 2Health News:Some astronauts at risk for cognitive impairment, animal studies suggest 3
... international body of knowledge to Texas,research center in ... The University of,North Texas Health Science Center ... recently added several new members to its faculty,to ... and,osteopathic manipulative medicine., Anuja Ghorpade has joined ...
... WALTHAM, Mass., Nov. 21 Inverness Medical,Innovations, Inc. (Amex: ... announced public offering on Tuesday. The Company sold a ... offering price of $61.49,per share. The total number of ... the underwriters upon their exercise of their,over-allotment option in ...
... 30,000 Clinic Locations, WASHINGTON, Nov. 21 ... announced the week after Thanksgiving,November 27 to December ... recommendations, influenza vaccination (flu shot) rates in young,children ... age 6 to 23,months were fully immunized for ...
... ATLANTA, Nov. 21 Eclipsys Corporation(R),(Nasdaq: ECLP ... be,participating in the Merrill Lynch Health Services Investor ... (Logo: http://www.newscom.com/cgi-bin/prnh/20050209/FLW006LOGO ), Eclipsys ... 28th at 10:00 a.m. Eastern time. Interested parties ...
... Czymmek, as he points to the video on his computer ... fireworks flash across the screen with every pulsation of the ... there is a large release of calcium with every heartbeat. ... a major problem--perhaps even heart failure. , Czymmek has a ...
... Nov. 21 Amylin Pharmaceuticals,Inc. (Nasdaq: AMLN ... Development (R&D),Day on Wednesday, November 28, 2007 at ... New York., "Amylin is focused on bringing ... our sustainable approach to the,discovery and development of ...
Cached Medicine News:Health News:UNT Health Science Center Appoints Eight New Faculty Members 2Health News:UNT Health Science Center Appoints Eight New Faculty Members 3Health News:Inverness Medical Innovations Announces Closing of Public Offering 2Health News:Asthma Foundation Offers National Flu Shot Finder 2Health News:Eclipsys to Present at the Merrill Lynch Health Services Investor Conference 2Health News:Eclipsys to Present at the Merrill Lynch Health Services Investor Conference 3Health News:New microscope peers into secret lives of cells 2Health News:New microscope peers into secret lives of cells 3Health News:Amylin Pharmaceuticals to Present at Research & Development Day 2
(Date:1/15/2014)... Foundation today announced it has established a relief fund ... weather that has gripped much of the nation. AARP and ... to support these emergency relief efforts AARP and AARP Foundation ... up to $500,000 in aid. The matching program will be ...
(Date:1/15/2014)... Shire plc (LSE: SHP, NASDAQ: SHPG ) announces that ... to the announced tender offer for all of the outstanding shares ... of the waiver, the transaction is no longer conditional on OFT ... 24, 2014 following the currently scheduled expiration time, subject to the ...
(Date:1/15/2014)... an unprecedented effort to curb the spread of "superbugs" such as ... an advanced and portable UV germicidal lamp manufactured by MRSA-UV is ... In order to prevent EMS paramedics and transport patients ... Palm Beach Fire Rescue is the first in the ...
Breaking Medicine Technology:AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 2AARP Foundation Establishes Winter Relief Fund for Older Adults Suffering from the Severe Cold Weather 3Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 2Shire Waives OFT Condition Relating to the Acquisition of ViroPharma Inc. 3Superbugs No Longer Ride In Rescue Vehicles 2
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
Medicine Products: