Navigation Links
Adverse events rate is low when propofol is administered by trained professional
Date:3/3/2010

Propofol is safe for advanced endoscopic procedures with a low rate of sedation-related adverse events when administered by a trained professional, according to a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association (AGA) Institute.

"This is the first paper to report the frequency of airway modifications (AMs) associated with propofol use in endoscopy. We believe that the need to perform AMs highlights the importance of a trained professional, such as a nurse anesthetist, who is solely responsible for maintenance of sedation and patient monitoring while using propofol," said Sreenivasa S. Jonnalagadda, MD, of the Washington University School of Medicine and lead author of the study. "Perhaps the highest-risk patients should be managed by nurse anesthetists trained in advanced airway interventions, whereas lower-risk patients can be safely managed by professionals with less intensive airway training."

Doctors prospectively studied patients undergoing sedation with propofol for advanced endoscopic procedures, including endoscopic retrograde cholangiopancreatography, endoscopic ultrasound and small bowel enteroscopy; a total of 799 patients were enrolled over seven months. Sedative dosing was determined by a certified registered nurse anesthetist with a goal of achieving deep sedation. Sedation-related complications included 154 AMs performed in 115 patients, such as 97 chin lifts, 29 modified face mask ventilations and 28 nasal airways. Additional complications included hypoxemia (deficient oxygenation of the blood, 12.8 percent); hypotension requiring vaso-pressors (abnormally low blood pressure, 0.5 percent); and early procedure termination (0.6 percent); these rates are comparable to other published data.

Elevated BMI, male sex and American Society of Anesthesiologist class greater than or equal to three were found to be independent predictors of patients
'/>"/>

Contact: Alissa J. Cruz
media@gastro.org
301-272-1603
American Gastroenterological Association
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Quantros Licenses Adverse Event Identification Technology from University of Michigan
2. News brief: Adverse symptom reporting by patients vs. clinicians
3. Morpace Reports: H1N1 Flu Could Adversely Impact Holiday Shopping Season
4. Social Isolation Adversely Affects Breast Cancer
5. Cogent trial shows lack of adverse interaction between clopidogrel and stomach medicine
6. Headache Publication Describes Potential Mechanistic Rationale for LEVADEX(TM) Favorable Adverse Event Profile
7. Despite ongoing safety concerns, study finds adverse reactions from contrast agents rarely occur
8. National Poll Finds Most Americans Believe Immigration Adversely Affects the Quality and Cost of Healthcare
9. Study finds adverse effects in treatment for primary sclerosing cholangitis
10. Reglan Adverse Events More Than Doubled from 2006 to 2008
11. Abbotts XIENCE V(R) Demonstrates Impressive Low Rates of Repeat Procedure, Stent Thrombosis and Major Adverse Cardiac Events in Complex, Real World Patients in SPIRIT V Study
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/22/2014)... stenting to open blockages in the kidney arteries ... from modern clinical trials, according to new recommendations ... and Cardiovascular Interventions today by the Society ... Hospitals Case Medical Center,s Sahil Parikh, MD, Director, ... Case Western Reserve University School of Medicine was ...
(Date:8/22/2014)... 2014 (HealthDay News) -- Counseling may do little to ... finds. Researchers analyzed 66 studies that included nearly ... at high risk for drinking problems. Participants in 49 ... in the rest of the studies attended group sessions ... A counseling technique called motivational interviewing was used in ...
(Date:8/22/2014)... A new, online conference is coming August 25th-29th, 2014 about ... open to everyone. Over 20 top experts will be ... how to stop emotional eating, start eating healthier and successful ... not a diet. The concept is about how to make ... don't eat that" approach. , You can sign up for ...
(Date:8/22/2014)... 22, 2014 Key West Health & ... revealed their much anticipated study results of the 12 ... and released an accompanying infographic on their website. It ... have a major impact on the skin and contribute ... more. , When asked how they determined the results, ...
(Date:8/22/2014)... Medical Oncology (ESMO), the leading pan-European organisation representing ... three outstanding individuals receiving the Society,s esteemed annual ... Bokemeyer, Heikki Joensuu and Peter Boyle on the ... Madrid, Spain. , Carsten Bokemeyer will receive the ... transition of cancer discovery into real benefit at ...
Breaking Medicine News(10 mins):Health News:UH Case Medical Center's Dr. Parikh authors SCAI paper on renal artery stenosis treatment 2Health News:UH Case Medical Center's Dr. Parikh authors SCAI paper on renal artery stenosis treatment 3Health News:Counseling Does Little to Deter Youth Drinking, Review Finds 2Health News:20 Top Experts Discuss How to Unravel the Food-Mood Connection 2Health News:Key West Health & Beauty Announces The 12 Best & Worst U.S. Cities For Skin Study 2Health News:ESMO honors outstanding oncology professionals 2Health News:ESMO honors outstanding oncology professionals 3
... , FRIDAY, April 27 (HealthDay News) -- Two genetic ... as primary open-angle glaucoma, according to new research. Glaucoma ... U.S. National Eye Institute said in a news release. ... worldwide, is due to irreversible damage to the optic nerve," ...
... the structure of a key part of the human obesity ... which could help provide new treatments for the complications of ... in the journal Structure , will greatly enhance the ... the receptor for the obesity hormone leptin. This could have ...
... , FRIDAY, April 27 (HealthDay News) -- Children who are bullied ... time they are 12 years old, according to a new study. ... the United Kingdom said its findings, published online April 27 in ... for this type of behavior. Examples of self-harming behaviors ...
... 5th Annual Jean Sindab Triple Negative Breast Cancer ... Emory University, provides an intimate learning environment in ... cancers (TNBC) will be explored. Nationally recognized speakers ... on current research in TNBC. TNBC affects young ...
... the discovery of small molecules that kill cancer cells ... results, in both cell and mouse models, demonstrate that ... by viral proteins, thus killing the infected tumor cells. ... April 20 issue of the journal Chemistry & ...
... ATLANTA April 26, 2012 New guidelines from ... a healthy weight, getting adequate physical activity, and eating ... and increase the likelihood of disease-free survival after a ... and Physical Activity Guidelines for Cancer Survivors, published early ...
Cached Medicine News:Health News:Research Gets Closer to Genetic Roots of Glaucoma 2Health News:New drug to tackle fat problems 2Health News:Bullied Children at Greater Risk for Self-Harm, Study Finds 2Health News:Small molecular bodyguards kill HPV-infected cancer cells by protecting tumor-suppressor 2Health News:Small molecular bodyguards kill HPV-infected cancer cells by protecting tumor-suppressor 3Health News:Guidelines say diet, exercise, weight control improve odds after cancer diagnosis 2Health News:Guidelines say diet, exercise, weight control improve odds after cancer diagnosis 3
(Date:8/22/2014)... , Aug. 22, 2014  Cannabis Science, Inc. ... formulation-based drug development and related consulting, is pleased ... international medical cannabis conference taking place at the ... , on October 22, 2014.  The multilingual ... such as researchers, health professionals, and patients, to ...
(Date:8/22/2014)...  WaferGen Bio-systems, Inc. (NASDAQ: WGBS) today announced the ... common stock and warrants at a price of $10,000 ... to deducting underwriting discounts and commissions and offering expenses ... immediately separable and will be issued separately.  The shares ... The NASDAQ Stock Market under the ticker symbol "WGBS" ...
(Date:8/21/2014)... Aug. 21, 2014  Vermillion, Inc. (NASDAQ: ... cancers and women,s health, has appointed Holly B. ... Markets. Ms. Bauzon has a proven track ... coverage for laboratory services companies. She has more than ... Inc., where she held the position of Director, Lab ...
Breaking Medicine Technology:Cannabis Science, Inc. (CBIS) to Sponsor 3rd International Conference on Cannabinoids in Medicine in October 2014 in Strasbourg, France 2Cannabis Science, Inc. (CBIS) to Sponsor 3rd International Conference on Cannabinoids in Medicine in October 2014 in Strasbourg, France 3WaferGen Bio-Systems Announces Pricing of $20 Million Underwritten Offering and Uplisting to NASDAQ 2WaferGen Bio-Systems Announces Pricing of $20 Million Underwritten Offering and Uplisting to NASDAQ 3WaferGen Bio-Systems Announces Pricing of $20 Million Underwritten Offering and Uplisting to NASDAQ 4Vermillion Appoints Holly B. Bauzon as VP of Sales and Managed Markets 2
... from a Phase 1/2 study of perifosine in combination ... from or refractory to bortezomib , ... Biopharmaceuticals, Inc. (Nasdaq: KERX ) today announced ... combination with bortezomib (+/- dexamethasone) in patients with relapsed/refractory ...
... SOUTH SAN FRANCISCO, Calif., Dec. 9 Portola,Pharmaceuticals, ... advances in cardiovascular disease, inflammatory disease,and cancer, today ... a large Phase II clinical trial of PRT060128, ... undergoing non-urgent,percutaneous coronary intervention (PCI). , ...
Cached Medicine Technology:Keryx Biopharmaceuticals, Inc. Reports Phase 1/2 Data on KRX-0401 (Perifosine) at 50th Annual Meeting of American Society of Hematology 2Keryx Biopharmaceuticals, Inc. Reports Phase 1/2 Data on KRX-0401 (Perifosine) at 50th Annual Meeting of American Society of Hematology 3Keryx Biopharmaceuticals, Inc. Reports Phase 1/2 Data on KRX-0401 (Perifosine) at 50th Annual Meeting of American Society of Hematology 4Keryx Biopharmaceuticals, Inc. Reports Phase 1/2 Data on KRX-0401 (Perifosine) at 50th Annual Meeting of American Society of Hematology 5Keryx Biopharmaceuticals, Inc. Reports Phase 1/2 Data on KRX-0401 (Perifosine) at 50th Annual Meeting of American Society of Hematology 6Keryx Biopharmaceuticals, Inc. Reports Phase 1/2 Data on KRX-0401 (Perifosine) at 50th Annual Meeting of American Society of Hematology 7Portola Pharmaceuticals Initiates Phase II Trial of Novel IV and Oral Anti-Platelet Drug in Non-Urgent Percutaneous Coronary Intervention 2Portola Pharmaceuticals Initiates Phase II Trial of Novel IV and Oral Anti-Platelet Drug in Non-Urgent Percutaneous Coronary Intervention 3
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
Medicine Products: