Navigation Links
Advances in brain imaging can expedite research and diagnosis in Alzheimer's disease
Date:10/11/2011

e healthy people, too much money, and too many years to evaluate the range of promising presymptomatic treatments using clinical endpoints," says lead author Eric M. Raiman, of the Banner Alzheimer's Institute and the University of Arizona. The project will use brain imaging studies, cerebrospinal fluid biomarkers, and cognitive measures to evaluate AD-modifying treatments earlier than is otherwise possible and to determine the extent to which the treatment's brain imaging and other biomarker effects predict a clinical benefit, among other outcomes.

Dr. Ashford comments that "even when imaging data are not applied to the management of individual patients, these data have the potential to assist in evaluating other components of care and diagnosis. To the extent that imaging can more sensitively measure brain integrity than existing techniques, novel treatments may be discovered because beneficial effects of treatments are not detectable with other methods."

Two articles in the supplement offer intriguing insights into the relationship between cortical thinning and AD. In "Relationship Between CSF Biomarkers of Alzheimer's Disease and Rates of Regional Cortical Thinning in ADNI Data," investigators from the Department of Veterans Affairs Medical Center, San Francisco, the University of California and the Hospital of the University of Pennsylvania tested the association between rates of regional brain cortex thinning and reduced amyloid (Ab1-42) and higher tau concentrations. Using data from the Alzheimer's Disease Neuroimaging Initiative, they found that these biomarkers were associated with increased rates of brain tissue loss, and that the patterns varied across the healthy elderly and the mildly cognitively impaired. "The finding of faster progression of brain atrophy in the presence of lower Ab1-42 levels and higher p-tau levels supports the hypothesis that they are measures of early AD pathology," says lead author Duygu Tosun.

'/>"/>
Contact: Daphne Watrin
d.watrin@iospress.nl
31-206-883-355
IOS Press
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. GEN reports on advances in DNA vaccine delivery and production
2. Advances in delivery of therapeutic genes to treat brain tumors
3. New advances in lipid genetics lead to better detection and prevention of major diseases
4. Led by advances in chemical synthesis, scientists find natural product shows pain-killing properties
5. Society of Interventional Radiology addresses radiation safety, advances best practices
6. Experts to discuss advances in dental sleep medicine treatments for sleep-disordered breathing
7. UT Southwestern research advances fight against kidney cancer
8. Research presented at 2011 GU Cancers Symposium highlights advances in treatment of prostate cancer
9. RIC study suggests researchers are entering a new era of advances in brain research
10. Long-shot discovery may lead to advances in treating anxiety, memory disorders
11. Roundup: 2010 Advances in Heart Disease and Stroke Care
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/22/2015)... Bradley, Illinois (PRWEB) January 22, 2015 Deer ... -- will host a Valentine’s Day Happy Hour from 3 p.m. ... located at 12500 Regency Parkway in Huntley, Illinois, serves adults with ... Happy Hour event will include Valentine's Day treats, games and sweetheart-themed ...
(Date:1/22/2015)... Woodloch Pines, an all-inclusive family resort located in ... number one best large hotel for families in the United ... annual Travelers’ Choice Awards. , TripAdvisor represents the world’s ... to millions of unbiased and honest traveler reviews. The best ...
(Date:1/22/2015)... (PRWEB) January 23, 2015 Angelweddingdress is a ... business invites its customers to follow it on Facebook, Twitter, ... a Valentine’s Day gift. Angelweddingdress draws a lottery every week. ... Sale to Feb. 28, 2015. Click Angelweddingdress homepage ...
(Date:1/22/2015)... Dallas, TX (PRWEB) January 22, 2015 ... the issue of experience and person-centeredness in the long-term ... moving towards action across the continuum. The paper, “The ... the Continuum,” engages perspectives and practices of the patient, ...
(Date:1/22/2015)... Joan Lunden, award-winning American journalist, beloved ... upcoming 32nd Annual Miami Breast Cancer Conference ... LLC (PER®) , shares that “a fast-growing, virulent” cancer ... she had not followed up her clean mammogram with ...
Breaking Medicine News(10 mins):Health News:Deer Path of Huntley Affordable Assisted Living to Host Valentine's Day Happy Hour 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 2Health News:TripAdvisor Names Woodloch Pines Best Hotel for Families in America 3Health News:Angelweddingdress Invites Its Customers To Follow It On Facebook, Twitter, And Pinterest 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 2Health News:The Power of Person-Centeredness in Long-Term Care Explored by The Beryl Institute 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 2Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 3Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 4Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 5Health News:Joan Lunden Reveals Diagnostic Approach That Led To Early Detection;To Keynote 32nd Annual Miami Breast Cancer Conference® 6
... Target for Pharmaceutical Companies Wishing to Grow Their Patient ... ResourcesWALTHAM, Mass., Jan. 22 /PRNewswire/ -- Decision ... firms focusing on pharmaceutical and healthcare issues, finds that ... in the number of untreated HIV patients in the ...
... Jan. 22 Americans United for Life (AUL) today ... least pro-life states. Pennsylvania, Louisiana, and South Dakota ... lowest."AUL,s annual ranking highlights the significant progress we are ... Dr. Charmaine Yoest, AUL President & CEO. "There ...
... SEGUNDO, Calif., Jan. 22 /PRNewswire/ -- Interactive lifestyle ... the newest tool in the fight against weight gain - ... television network and hsn.com on January 26. Developed by ... years of his research linking human olfactory senses to appetite ...
... Forterus Healthcare, a division of Forterus Inc. (OTC ... Solutions 4 Recovery, a Dana Point, Calif.-based drug and ... 1 2009Forterus Healthcare will operate Solutions 4 Recovery as ... Recovery is the second behavioral health care acquisition made ...
... Limited (Nasdaq: WCRX ) announced today that ... close on Tuesday, January 27, 2009. In addition to ... Executive Officer and Paul Herendeen, Executive Vice President and ... audio webcast to discuss the 2009 Financial Guidance for ...
... China Medical Technologies,Inc. (the "Company") (Nasdaq: ... develops, manufactures and markets advanced in-vitro diagnostic,products, today ... its,Prenatal FISH Probe and Cervical Cancer FISH Probe ... in the People,s Republic of China (the "PRC"). ...
Cached Medicine News:Health News:Georgia Ranks Fourth in the Number of Untreated HIV Patients in the United States 2Health News:Georgia Ranks Fourth in the Number of Untreated HIV Patients in the United States 3Health News:Pennsylvania Most Pro-Life State in America, California Least, According to Americans United for Life State Rankings 2Health News:HSN to Debut Sensa Weight-Loss System January 26 2Health News:Forterus Healthcare to Acquire Solutions 4 Recovery 2Health News:China Medical Technologies Announces the Receipt of SFDA Approval for Two of its FISH Probes and the Approval for the Hi-Tech Enterprise Status for its PRC Subsidiaries 2Health News:China Medical Technologies Announces the Receipt of SFDA Approval for Two of its FISH Probes and the Approval for the Hi-Tech Enterprise Status for its PRC Subsidiaries 3
(Date:1/23/2015)... Jan. 23, 2015  HyGreen, Inc., a leader in hand ... with RCA Medical, a subsidiary of Ascendis Health Limited, ... Each year, hundreds of millions of patients around ... organisms are transmitted from patient to patient via the ...
(Date:1/23/2015)... N.Y. , Jan. 23, 2015  Lixte Biotechnology Holdings, Inc. ... its Phase I trial of Lixte,s lead compound, LB‑100, is ... John S. Kovach , M.D., the founder ... planned to be completed at a single site. Accrual of ...
(Date:1/23/2015)... Jan. 23, 2015  CytoSorbents Corporation (NASDAQ CM: CTSO), ... extracorporeal cytokine adsorber to reduce deadly inflammation in ... of $385,642, net of transaction costs, in non-dilutive ... Business Tax Certificate Transfer Program sponsored by the ...
Breaking Medicine Technology:HyGreen Partners with RCA Medical in Johannesburg, South Africa 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 2Lixte Biotechnology Holdings Announces Expansion Of Clinical Sites For Its Phase I Trial Of Its Lead Anti-Cancer Compound, LB-100 3CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 2CytoSorbents Receives $385,000 in Non-Dilutive Funding from the New Jersey Technology Business Tax Certificate Transfer Program 3
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
Medicine Products: