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Advances in brain imaging can expedite research and diagnosis in Alzheimer's disease
Date:10/11/2011

Amsterdam, The Netherlands, 11 October 2011 Alzheimer's disease (AD) is a common problem that is becoming progressively burdensome throughout the world. A new supplement to the Journal of Alzheimer's Disease, Imaging the Alzheimer Brain, clearly shows that multiple imaging systems are now available to help understand, diagnose, and treat the disease.

"Alzheimer's disease is now seen as a continuum that is influenced by factors early in life, including genetics and education," according to Guest Editor J. Wesson Ashford, MD, PhD, Clinical Professor and Senior Research Scientist at the Stanford/VA Alzheimer Center, Palo Alto, CA. "Conceptualizing the continuum of AD with advanced imaging technology will provide a greater understanding of the disease, and help advance diagnosis and the quest for prevention and treatment."

The supplement features both reviews of the basic concepts of neuroimaging in the context of AD, the latest developments in imaging, and various discussions and perspectives of the problems of the field and promising directions. It provides in-depth insights into: pathology and pathophysiological bases of AD; structural and cerebral blood flow imaging; metabolism, amyloid plaques, and neurofibrillary tangles in vascular co-morbidity and AD; current advances in functional magnetic resonance imaging for detecting AD; electromagnetic brain mapping; diffusion tensor imaging; magnetic resonance spectroscopy; and longitudinal neuroimaging measures.

Investigators have used brain imaging to track some of the earliest changes associated with the predisposition to AD. In their paper, "Alzheimer's Prevention Initiative: A Plan to Accelerate the Evaluation of Presymptomatic Treatments," a group of scientists proposes to evaluate investigational treatments in healthy people who, based on their age and genetic background, are at the highest imminent risk of developing symptomatic AD. "It currently takes too many averag
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Contact: Daphne Watrin
d.watrin@iospress.nl
31-206-883-355
IOS Press
Source:Eurekalert

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