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Advances in Genetic Understanding and Treatment Protocols Lead to Significant Progress in Leukemia and Myeloproliferative Disorders
Date:12/5/2009

NEW ORLEANS, Dec. 5 /PRNewswire-USNewswire/ -- Leukemia and myeloproliferative disorders are serious and often deadly blood cancers. Research presented today at the 51st Annual Meeting of the American Society of Hematology introduces potential new treatment options and improved diagnostic methods for patients suffering from acute promyelocytic leukemia, chronic myeloid leukemia, infant acute lymphoblastic leukemia, and myelofibrosis that are based on a better understanding of the underlying genetic causes of these conditions.

"Researchers are committed to improving the survival of patients with blood cancers and other bone marrow disorders like myelofibrosis," said moderator of the press conference Richard A. Larson, MD, Professor of Medicine at the University of Chicago. "We hope that the results of these studies will help us develop safer and more effective treatments, especially in those hard-to-treat conditions where we currently do not have many options."

This press conference will take place on Saturday, December 5, at 8:30 a.m.

Improving the Treatment Outcome of Acute Promyelocytic Leukemia in Developing Countries Through International Cooperative Network. Report on the International Consortium on Acute Promyelocytic Leukemia Study Group [Abstract #6]

In developed countries, the standard treatment for acute promyelocytic leukemia (APL), as recommended by evidence-based guidelines such as those of the EuropeanLeukemiaNET, is a combination of all-trans retinoic acid, a derivative of Vitamin A, and an anthracycline-based chemotherapy; this results in a five-year overall survival rate of approximately 90 percent. The morbidity and mortality of APL in patients in developing countries is significantly higher. Researchers from the International Consortium on Acute Promyelocytic Leukemia (IC-APL), an initiative of the American Society of Hematology, aimed to reduce this difference in surv
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SOURCE American Society of Hematology
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