Navigation Links
Advanced technology reveals activity of single neurons during seizures
Date:3/27/2011

The first study to examine the activity of hundreds of individual human brain cells during seizures has found that seizures begin with extremely diverse neuronal activity, contrary to the classic view that they are characterized by massively synchronized activity. The investigation by Massachusetts General Hospital (MGH) and Brown University researchers also observed pre-seizure changes in neuronal activity both in the cells where seizures originate and in nearby cells. The report will appear in Nature Neuroscience and is receiving advance online publication.

"Our findings suggest that different groups of neurons play distinct roles at different stages of seizures," says Sydney Cash, MD, PhD, of the MGH Department of Neurology, the paper's senior author. "They also indicate that it may be possible to predict impending seizures, and that clinical interventions to prevent or stop them probably should target those specific groups of neurons."

Epileptic seizures have been reported since ancient times, and today 50 million individuals worldwide are affected; but much remains unknown about how seizures begin, spread and end. Current knowledge about what happens in the brain during seizures largely comes from EEG readings, which reflect the average activity of millions of neurons at a time. This study used a neurotechnology that records the activity of individual brain cells via an implanted sensor the size of a baby aspirin.

The researchers analyzed data gathered from four patients with focal epilepsy seizures that originate in abnormal brain tissues that could not be controlled by medication. The participants had the sensors implanted in the outer layer of brain tissue to localize the abnormal areas prior to surgical removal. The sensors recorded the activity of from dozens to more than a hundred individual neurons over periods of from five to ten days, during which each patient experienced multiple seizures. In some
'/>"/>

Contact: Sue McGreevey
smcgreevey@partners.org
617-724-2764
Massachusetts General Hospital
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Racial disparities persist in the diagnosis of advanced breast cancer and colon cancer in the U.S.
2. UH Case Medical Center researchers publish promising findings for advanced cervical cancer
3. Split-course palliative radiotherapy confirmed as effective treatment for advanced NSCLC
4. Drug for advanced kidney cancer shrinks tumors prior to surgery
5. Siemens Awards for Advanced Placement Honor Top U.S. Science and Math Students and Teachers
6. Family members reduce stress in advanced cancer patients with 14 minute massages
7. Accelerated radiation therapy reduces toxicity in patients with advanced head and neck cancers
8. Proton beam therapy shows encouraging long-term outcome for patients with locally advanced sinonasal cancers
9. Castrate-Metastatic Prostate Cancer: Therapeutic Considerations for Advanced Disease
10. AdvancedMD Appoints William Stone Vice President and General Manager of Billing Services Partner Program
11. BOTOX Cosmetic & Wrinkle Filler Specialist Hosts Advanced Training Event at Ageless Beauty in Mountain Home, ID
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/14/2014)... July 14, 2014 BCC Research ... SYNTHETIC BIOLOGY: GLOBAL MARKETS , the global ... nearly $11.9 billion in 2018, with a five-year ... products account for the fastest growing segment, with ... Synthetic biology-enabled products in the pharmaceutical/diagnostics, chemical, energy, ...
(Date:7/14/2014)... The Encino cosmetic dentist at Encino ... and porcelain veneers. These restorations are an excellent alternative ... greater loss of healthy tooth tissue. They work similarly ... on the tooth. Encino dentist Dr. Mastour and his ... they offer the most appropriate treatment recommendations for each ...
(Date:7/14/2014)... Gray HealthDay Reporter ... suggests that a faltering sense of smell might signal ... inexpensive, low-tech smell test could spot who needs more ... the decreased ability to identify odors was associated with ... Alzheimer,s disease. "We,re trying to be able to ...
(Date:7/14/2014)... HealthDay Reporter MONDAY, July ... linked to multiple health issues, but dementia isn,t one of ... widowhood may even delay dementia, the researchers found. "For ... was associated with a later age of developing full-blown dementia ... Bryan Woodruff. Woodruff, an assistant professor of neurology ...
(Date:7/14/2014)... Skin M.D. by ... on Monday, July 14th, located at 45 East ... last all week through Saturday, July 19th, with ... welcomed to attend. The business is owned by ... anti-aging, weight loss services, and sells high-end industry ...
Breaking Medicine News(10 mins):Health News:Global Market for Synthetic Biology to Reach Nearly $11.9 Billion by 2018 — Enabled Products Account for the Fastest Growing Segment with 36.7% CAGR 2Health News:Global Market for Synthetic Biology to Reach Nearly $11.9 Billion by 2018 — Enabled Products Account for the Fastest Growing Segment with 36.7% CAGR 3Health News:Encino Esthetic Dental Group is Now Offering Lumineers and Porcelain Veneers 2Health News:Could a Simple Smell Test Help Spot Alzheimer's Early? 2Health News:Could a Simple Smell Test Help Spot Alzheimer's Early? 3Health News:Widowhood May Delay Dementia in Some Seniors, Study Finds 2Health News:Widowhood May Delay Dementia in Some Seniors, Study Finds 3Health News:The Cosmetic Medic Announces Grand Opening of New Skin M.D., a Physician-Administered Anti-aging, Skincare, and Weight Loss Practice 2Health News:The Cosmetic Medic Announces Grand Opening of New Skin M.D., a Physician-Administered Anti-aging, Skincare, and Weight Loss Practice 3
... hunger strike to protest against the raising of the Narmada ... attending on her Sunday. // ,"Medha Patkar has ... doctor at the All India Institute of Medical Sciences (AIIMS) ... ,AIIMS medical superintendent D.K. Sharma said that Patkar's ...
... strapped for cash are planning on letting go of staff and ... Hospital in Wolverhampton, a hospital in such a crisis which has ... hoping to save about ?2.5 million a year. The management hope ... medical secretary bill by sending voice recordings over the internet to ...
... a Melbourne study australians go to hospitals with injuiries due ... latest issue of the Medical// Journal of Australia. ... to falls of all hospital cases. ,Associate Professor ... Centre led the study and incorporated a falls prevention ...
... diet can influence corrective behaviour in prisoners.// ... product of poor nutrition was tested in a prison ... less violent when put on a diet rich in ... paper titled “Seafood Consumption and Homicide Mortality”, raised this ...
... UK has fallen to its lowest levels since such records ... Suicide Prevention Strategy. The report also shows //a drop in ... well as a decline in the number of suicides among ... major cause of preventable death in England and elsewhere. At ...
... chemicals that could trigger inflammation leading to deterioration of ... the crucial link between obesity and heart disease. ... that fat cells lying close to blood vessels in ... influence biological processes within the body, reported the online ...
Cached Medicine News:
(Date:7/14/2014)... ANAHEIM, Calif. , July 14, 2014  Mallinckrodt ... (NASDAQ: QCOR ) today announced that the registration ... Exchange Commission ("SEC") by Mallinckrodt plc on May 16, 2014 ... proxy statement of Mallinckrodt and Questcor that also constitutes a ... The registration statement on Form S-4 is available on the ...
(Date:7/14/2014)... BEIJING , July 14, 2014 Sinovac Biotech Ltd. (NASDAQ: ... China , announced today that it will hold its 2014 ... Beijing Time. The meeting will be held at No. 39 Shangdi Xi ... record as of July 9, 2014 will be eligible to vote and ... is to approve the re-election of Weidong Yin , Yuk ...
(Date:7/14/2014)... and LONDON , July 14, 2014 ... IXICO plc (AIM: IXI) jointly announced today the formation ... companies. Dr. Edward Ashton , Ph.D., chief scientific ... have seven members. "The formation of this ... the international commercial and operational alliance we signed with ...
Breaking Medicine Technology:Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 2Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 3Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 4Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 5Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 6Mallinckrodt Pharmaceuticals And Questcor Pharmaceuticals Provide Update On Transaction 7Sinovac Schedules 2014 Annual Meeting of Shareholders 2Sinovac Schedules 2014 Annual Meeting of Shareholders 3VirtualScopics, Inc. And IXICO plc Announce The Formation Of A Scientific Advisory Board To Benefit Both Companies; Dr. Edward Ashton, Ph.D. Appointed Chairman 2VirtualScopics, Inc. And IXICO plc Announce The Formation Of A Scientific Advisory Board To Benefit Both Companies; Dr. Edward Ashton, Ph.D. Appointed Chairman 3VirtualScopics, Inc. And IXICO plc Announce The Formation Of A Scientific Advisory Board To Benefit Both Companies; Dr. Edward Ashton, Ph.D. Appointed Chairman 4VirtualScopics, Inc. And IXICO plc Announce The Formation Of A Scientific Advisory Board To Benefit Both Companies; Dr. Edward Ashton, Ph.D. Appointed Chairman 5VirtualScopics, Inc. And IXICO plc Announce The Formation Of A Scientific Advisory Board To Benefit Both Companies; Dr. Edward Ashton, Ph.D. Appointed Chairman 6VirtualScopics, Inc. And IXICO plc Announce The Formation Of A Scientific Advisory Board To Benefit Both Companies; Dr. Edward Ashton, Ph.D. Appointed Chairman 7VirtualScopics, Inc. And IXICO plc Announce The Formation Of A Scientific Advisory Board To Benefit Both Companies; Dr. Edward Ashton, Ph.D. Appointed Chairman 8VirtualScopics, Inc. And IXICO plc Announce The Formation Of A Scientific Advisory Board To Benefit Both Companies; Dr. Edward Ashton, Ph.D. Appointed Chairman 9
... by genomics, SAN DIEGO, April 14 ... Therapeutics, Inc. (CTI) (Nasdaq,and MTAX: CTIC), presented data ... patients more likely to respond to treatment with ... for,Cancer Research (AACR) annual meeting. These findings will ...
... April 13 Researchers from the,Barbara Ann ... findings,showing that adding curcumin or resveratrol to ... growth of chemo-resistant colon cancer,cells. The poster ... Cancer Research (AACR) Annual Meeting in San ...
Cached Medicine Technology:New Gene Discovery Suggests Which Patients CTI's Brostallicin May Benefit 2New Gene Discovery Suggests Which Patients CTI's Brostallicin May Benefit 3New Gene Discovery Suggests Which Patients CTI's Brostallicin May Benefit 4New Gene Discovery Suggests Which Patients CTI's Brostallicin May Benefit 5Karmanos Researchers Find Non-Toxic Agents Added to Conventional Chemotherapy Decrease Survival of Colon Cancer Cells 2
... an 125I radioimmunoassay designed for,in ... quantitative,measurement of estradiol in serum, ... in girls,and gynecomastia in men, ... amenorrhea. It is,also intended for ...
... determination of Estradiol (E2) concentration in human serum ... hormone with a phenolic A ring. This ... It is the most potent natural Estrogen, ... smaller amounts by the adrenal cortex, and the ...
... is the most potent, naturally secreted estrogen ... the ovary [1]. In the ovary, estradiol ... estrone, a less potent estrogen derived from ... many body tissues. In men, small amounts ...
... VITROS ECi brings true automation and ... testing. Highly sensitive assays for thyroid, ... bone metabolism testing are currently available, ... The VITROS ECi can simultaneously process ...
Medicine Products: