Navigation Links
Advanced targeted therapies effective as first-line treatment for lung cancer
Date:8/1/2009

ree survival (PFS, length of time during and after treatment when a patient's disease does not worsen) than those receiving chemo. Also, high-grade toxicity was less common in the gefitinib group than in the chemotherapy group.

Additionally, in the gefitinib group, PFS in the mutation-negative subgroup was shorter than that of the mutation-positive group (with a median of 2.1 vs. 8.4 months). There was no difference between these two subgroups in the chemotherapy group.

"Gefitinib did not improve overall survival over the standard chemotherapy," said Jin S. Lee, M.D. of the National Cancer Center Korea in Goyang, Korea. "However, a promising survival outcome along with high overall response rate and better toxicity profile suggests that gefitinib might be a reasonable first-line therapy for this group of never-smoker lung cancer patients."

Dr. Lee will present this study on Monday, August 3 at 9:35 am PT in Moscone West, Ballroom, Level 3.

EFFICIENCY OF MAINTENANCE ERLOTINIB VERSUS PLACEBO IN PATIENTS WITH UNRESECTABLE STAGE III NON-SMALL LUNG CANCER (NSCLC) FOLLOWING CONCURRENT CHEMORADIATION (D0410, NCT00153803) (ABSTRACT # C6.1)

Currently, the role of maintenance therapy following concurrent treatment with chemotherapy and radiotherapy (cCRT) in patients with unresectable stage III non-small lung cancer (NSCLC) remains undefined, and concern has been noted with maintenance therapies. To examine alternative treatment options, this trial was designed to evaluate the effectiveness of maintenance erlotinib following cCRT in unresectable stage III NSCLC patients.

In this upfront, randomized, placebo-controlled phase III trial, scientists randomly assigned 243 patients with unresectable stage III NSCLC to receive erlotinib or placebo daily following their cCRT.

In the intent-to-treat analysis, there was no statistically significant difference in the primary endpoint of progression-free survival (PF
'/>"/>

Contact: Liz Wulderk
lwulderk@spectrumscience.com
443-506-1931
International Association for the Study of Lung Cancer
Source:Eurekalert

Page: 1 2 3 4 5 6 7 8

Related medicine news :

1. Smith & Nephew Highlights Advanced Wound Management Progress
2. Patient safety advanced by revised heparin standards
3. AstraZeneca Submits New Drug Applications for ZACTIMA(TM) in Second-Line Advanced Non-Small Cell Lung Cancer
4. Penile Prosthesis Surgery Infection Rates Reduced With The No-Touch Technique By Dr. J. Francois Eid of Advanced Urological Care
5. Leading Independent Analyst Firm States Silver Creek Systems Holds A Virtual Monopoly In Delivering Advanced Product Data Quality Capabilities
6. Surgery remans an option for advanced lung cancer
7. Nexavar in Combination with Chemotherapy Shown to Extend Progression-Free Survival in Patients with Advanced Breast Cancer
8. Hendrick Health System Deploys Sentillions Tap & Go Advanced Authentication Solution
9. Centocor Ortho Biotech Statement on the FDA ODAC Opinion Regarding DOXIL(R) for Treatment of Advanced Breast Cancer
10. Marienkrankenhaus Hamburg Installs Visage(R) CS Enterprise Wide Advanced Visualization Solutions
11. Advanced Bag Design for Cryopreservation: The New CryoMACS(R) Freezing Bag
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/22/2014)... York, NY (PRWEB) December 22, 2014 ... noticeable toll and can present in the form of ... folds with the start of the marionette line or ... topical treatments and diligent skincare, but as the deep ... and Restylane are all synthetic fillers that can be ...
(Date:12/22/2014)... (PRWEB) December 22, 2014 Coral Gables is ... service , Lice Troopers, with its new clinic location set ... Florida, takes the hassle out of dealing with this common ... one of their two salon clinic locations in South Florida, ... location. , The decision to expand developed naturally out of ...
(Date:12/22/2014)... Angeles, CA (PRWEB) December 22, 2014 ... reputable PALS, BLS and ACLS online certification provider, are ... http://www.acls-pals-bls.com . The updated site now features a ... easier than ever to use. , As a ... peoples’ information is now consolidated into a single page ...
(Date:12/22/2014)... New York, New York (PRWEB) December 22, 2014 ... that are a staple of the season. Many may be ... pounds in a span of a few weeks. Health Republic ... the help of Registered Dietitian, Andrea Chernus, to provide some ... to eat and stay healthy. , 1)    Avoid arriving at a ...
(Date:12/22/2014)... Dec. 19, 2014 (HealthDay News) -- U.S. and state ... caramel apples that has killed at least four people ... should not eat any commercially produced, prepackaged caramel apples ... Disease Control and Prevention said in a news release. ... people had been infected with the outbreak strains of ...
Breaking Medicine News(10 mins):Health News:Sam Rizk, MD, FACS, Introduces Rapid Recovery Facelift 2Health News:Professional In-Home All-Natural Lice Removal Service Expands to Coral Gables and surrounding areas. 2Health News:ACLS Online Certification Website ACLS-PALS-BLS.com Now Features a New and User-Friendly Layout 2Health News:Health Republic Insurance of New York Offers Five Simple Tips to Eat Healthy During the Holidays 2Health News:CDC Warns of Listeria Danger From Caramel Apples 2
... leading causes of soldier attrition in modern war, with the ... are treated outside the theaters of operation. However, that rate ... and managed for pain in the field of instead of ... from a Johns Hopkins anesthesiologist. , The main factor seems ...
... PORTLAND, Ore. Researchers at Oregon Health & Science ... system in a study that suggests new strategies may ... against disease. The research is published in the current ... Science. , The research focused on an important component ...
... confirms cardiac safety, TAMPA, Fla., Dec. 17 ... leader in electro-stun technology, today,announced a major research ... Stinger Systems, S-200 projectile stun gun. Details of ... scientific meeting and/or,in a scientific journal. However, this ...
... New NutriSystem(R) Advanced(TM) Program, Available Today, Offers Great ... Taste, Less Hunger and Now Even More ... As millions of,Americans indulge -- and then bulge ... (NTRI) today announced consumer availability of,NutriSystem Advanced, the ...
... available antibiotic can improve the quality of life of ... health care savings. , Results of a study published ... Medicine, a top international journal, indicate that macrolide antibiotics ... asthma treatment. , The study was conducted by researchers ...
... diagnosed this year, American Cancer Society reports , , MONDAY, Dec. ... deadly swath across the globe, with the American Cancer Society ... 2007, with 7.6 million people dying from the disease. , ... that 5.4 million of those cancers and 2.9 million deaths ...
Cached Medicine News:Health News:Pain treatment in the field: Good for soldiers' comfort and better for rebuilding troop strength 2Health News:OHSU research suggests new strategy for protecting aging Americans against infectious disease 2Health News:Medical Study of Stinger S-200 Stun Gun Completed 2Health News:With Calorie Counting on Holiday Hiatus, NutriSystem Offers 'Advanced' Resolution for 2008 2Health News:With Calorie Counting on Holiday Hiatus, NutriSystem Offers 'Advanced' Resolution for 2008 3Health News:With Calorie Counting on Holiday Hiatus, NutriSystem Offers 'Advanced' Resolution for 2008 4Health News:Antibiotic treatment targets difficult asthma 2Health News:Cancer Killed Almost 8 Million Worldwide in 2007 2Health News:Cancer Killed Almost 8 Million Worldwide in 2007 3Health News:Cancer Killed Almost 8 Million Worldwide in 2007 4
(Date:12/19/2014)... WESTMINSTER, Colo. , Dec. 19, 2014  Monarch ... (f/k/a Cannabis Kinetics Corp.) is pleased to provide this ... for continued growth in 2015. "Over this ... corporate goals and I am extremely proud to say ... diversified position today than it has ever been," stated ...
(Date:12/19/2014)... FORT WORTH, Texas , December 18, 2014 ... is a networked software application/module that is used ... and related images. RIS comprises a patient tracking ... tracking system. The integration of RIS with HIS ... is used for patient registration and patient scheduling, ...
(Date:12/19/2014)... --Research and Markets ( http://www.researchandmarkets.com/research/942kh3/micro_market ) ... Market Monitor: North American Dermatology Diagnostic Devices Market" ... http://photos.prnewswire.com/prnh/20130307/600769 Cosmetic surgeries ... resulted in fueling the overall demand of the ... these dermatology devices is to assist in identifying ...
Breaking Medicine Technology:Monarch America Inc. CEO Reviews Recent Achievements and Provides Outlook for 2015 2Monarch America Inc. CEO Reviews Recent Achievements and Provides Outlook for 2015 3The Global Radiology Information Systems Market is Expected to Grow at a CAGR of 7.5% from 2014 to 2019 2The Global Radiology Information Systems Market is Expected to Grow at a CAGR of 7.5% from 2014 to 2019 3Micro Market Monitor: North American Dermatology Diagnostic Devices Market 2Micro Market Monitor: North American Dermatology Diagnostic Devices Market 3
... ACCESS PHARMACEUTICALS, INC . ... signed an agreement with iMedicor (OTC Bulletin Board: VMCI) for ... mucoadhesive oral rinse for the management of oral mucositis and ... targeted Alerts System application, initial introduction of MuGard to the ...
... R-Tech Ueno, Ltd. has started early Phase II clinical ... by the company -- a new compound targeted as a ... , Phase I clinical trial in healthy male volunteers that ... Early phase II clinical trial has been started for two ...
Cached Medicine Technology:Access Pharmaceuticals Signs eMarketing Agreement With iMedicor For MuGard(TM) 2Access Pharmaceuticals Signs eMarketing Agreement With iMedicor For MuGard(TM) 3Access Pharmaceuticals Signs eMarketing Agreement With iMedicor For MuGard(TM) 4R-Tech Ueno Starts Early Phase II Clinical Trial for RK-023 2R-Tech Ueno Starts Early Phase II Clinical Trial for RK-023 3
SOLOS Endoscopy shares your commitment to provide every patient with the highest quality care available through our ongoing research and development of advanced surgical instruments and diagnostic so...
Ethicon Endo-Surgery provides disposable handheld instruments that provide reliable, precise performance every time. Our handheld instruments come in 5mm and 10mm sizes....
... The Auto Suture™ ... inclusive of five (5) ... application in a variety ... urologic, colorectal and other ...
The ENDO MINI-RETRACT™ 5 mm instrument has application in a variety of gynecologic, abdominal, urologic, thoracic and endoscopic procedures for temporary retraction of tissue and small tubular ...
Medicine Products: