Navigation Links
Advanced Age No Bar to Liver Transplant
Date:8/23/2007

Patients over 70 did as well as those in their 50s, study found

THURSDAY, Aug. 23 (HealthDay News) -- Age alone doesn't increase the risk of death among liver transplant patients age 70 or older and shouldn't restrict liver transplantation in the elderly, a new study finds.

A team at the University of California, Los Angeles, David Geffen School of Medicine reviewed the records of 62 patients age 70 and older (average age 71.9 years) and 864 patients ages 50 to 59 (average age 54.3).

All of the patients received their first liver transplant between 1988 and 2005. The patients' survival time was measured until death, the last known follow-up date, or retransplantation.

Overall, 31 of the 62 patients age 70 and older and 345 of the 864 younger patients died during the study period. After one year, 73.3 percent of older patients and 79.4 percent of younger patients were alive. After 10 years, 39.7 percent of older patients and 45.2 percent of younger patients were alive.

According to the researchers, that means they found "no statistically significant difference in survival in the first 10 years after transplantation" between the two groups of patients.

"The longest-surviving patient was 88 years old at 15 years after transplantation. One-year adjusted survival of septuagenarians in the most recent surgical period, 2001 to 2005, was 94.4 percent," the team noted.

The researchers also analyzed 26 variables to determine which ones might predict patient death. They identified four: preoperative hospitalization; prolonged period of cold storage between liver removal and transplantation; cirrhosis caused by hepatitis C and alcohol; and an increasing model for end-stage liver disease (MELD) score, a measure of disease severity.

Being 70 or older was not an independent predictor of death, the authors said.

"In conclusion, biological and physiological variables may play a more important role than advanced age in predicting poor survival after liver transplantation," the UCLA team wrote. "Measures of physiological age and risk of complications should be used in the evaluation process of elderly transplant candidates. Age by itself should not be used to limit liver transplantation."

The study is published in the August issue of the journal Archives of Surgery.

More information

The American Liver Foundation has more about liver transplantation.



-- Robert Preidt



SOURCE: JAMA/Archives journals, news release, Aug. 20, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Innovative device aids in advanced heart failure
2. Advanced STD programs required
3. Light therapy devotes new hope in advanced lung cancer
4. Hope For Patients With Advanced Breast Cancer
5. Race an important links to the risk of advanced colorectal cancer
6. HIV Vaccine Field Trials In Advanced Stage
7. Twin Treatment Could Be Used Increase Survival Rates In Advanced Melanoma
8. NICE supports application of advanced biological therapies as treatment option for acute psoriasis
9. Eddie Thompson Receives Advanced Cancer Treatment
10. PSA Can Predicts The Treatment Response In Advanced Prostate Cancer
11. Rapid Aging of Arteries In People With Advanced Heart Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/23/2017)... ... July 23, 2017 , ... Technology is ... and patient-provider relationships. New tools are helping patients become more actively involved in ... Health Care’s Most Wired® survey, released today by the American Hospital Association’s (AHA) ...
(Date:7/23/2017)... ... July 23, 2017 , ... Longtime Brevard ... Group – Melbourne, a practice owned by Physician Partners of America at 109 ... Dr. Stern also is certified in pediatrics, emergency medicine and anesthesiology. , A ...
(Date:7/23/2017)... ... July 23, 2017 , ... Viora Ltd., a leading medical ... No. 9,038,640 by the United States Patent and Trademark Office. The patent applies ... Switching, Vacuum, and Cooling mechanisms to further increase the efficacy and safety of ...
(Date:7/22/2017)... (PRWEB) , ... July 22, 2017 , ... ... each year with the majority of patients not requiring pain medication after three ... for Sports Medicine’s Annual Meeting today in Toronto, Ontario, Canada found that ...
(Date:7/21/2017)... PITTSBURGH, PA (PRWEB) , ... July 21, 2017 , ... ... I use a lot of pleural catheters available on the market," said an inventor ... level of comfort and safety for the patient." , He developed the patent-pending PLEURAL ...
Breaking Medicine News(10 mins):
(Date:7/12/2017)... , July 12, 2017 CarpalAID is a revolutionary ... braces or surgery. Carpal tunnel syndrome affects more than ... at twice the rate of men. The common methods of treating ... mobilization with uncomfortable hand braces or gloves. ... CarpalAID is a clear patch ...
(Date:7/11/2017)... July 11, 2017  Sysmex America, Inc., a ... testing equipment as well as middleware information systems ... to make quality assurance easier and more risk ... well known for the innovation that it delivers ... elevates quality assurance processes to a new level ...
(Date:7/10/2017)... July 10, 2017  BDI Group subsidiary Pathway ... support services organization serving specialty pharmacies, home infusion ... of four significant, value-added member programs designed to ... manage reimbursement and improve access and affordability for ... Pathway ...
Breaking Medicine Technology: