Navigation Links
Advanced Age No Bar to Liver Transplant
Date:8/23/2007

Patients over 70 did as well as those in their 50s, study found

THURSDAY, Aug. 23 (HealthDay News) -- Age alone doesn't increase the risk of death among liver transplant patients age 70 or older and shouldn't restrict liver transplantation in the elderly, a new study finds.

A team at the University of California, Los Angeles, David Geffen School of Medicine reviewed the records of 62 patients age 70 and older (average age 71.9 years) and 864 patients ages 50 to 59 (average age 54.3).

All of the patients received their first liver transplant between 1988 and 2005. The patients' survival time was measured until death, the last known follow-up date, or retransplantation.

Overall, 31 of the 62 patients age 70 and older and 345 of the 864 younger patients died during the study period. After one year, 73.3 percent of older patients and 79.4 percent of younger patients were alive. After 10 years, 39.7 percent of older patients and 45.2 percent of younger patients were alive.

According to the researchers, that means they found "no statistically significant difference in survival in the first 10 years after transplantation" between the two groups of patients.

"The longest-surviving patient was 88 years old at 15 years after transplantation. One-year adjusted survival of septuagenarians in the most recent surgical period, 2001 to 2005, was 94.4 percent," the team noted.

The researchers also analyzed 26 variables to determine which ones might predict patient death. They identified four: preoperative hospitalization; prolonged period of cold storage between liver removal and transplantation; cirrhosis caused by hepatitis C and alcohol; and an increasing model for end-stage liver disease (MELD) score, a measure of disease severity.

Being 70 or older was not an independent predictor of death, the authors said.

"In conclusion, biological and physiological variables may play a more important role than advanced age in predicting poor survival after liver transplantation," the UCLA team wrote. "Measures of physiological age and risk of complications should be used in the evaluation process of elderly transplant candidates. Age by itself should not be used to limit liver transplantation."

The study is published in the August issue of the journal Archives of Surgery.

More information

The American Liver Foundation has more about liver transplantation.



-- Robert Preidt



SOURCE: JAMA/Archives journals, news release, Aug. 20, 2007


'/>"/>
Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Innovative device aids in advanced heart failure
2. Advanced STD programs required
3. Light therapy devotes new hope in advanced lung cancer
4. Hope For Patients With Advanced Breast Cancer
5. Race an important links to the risk of advanced colorectal cancer
6. HIV Vaccine Field Trials In Advanced Stage
7. Twin Treatment Could Be Used Increase Survival Rates In Advanced Melanoma
8. NICE supports application of advanced biological therapies as treatment option for acute psoriasis
9. Eddie Thompson Receives Advanced Cancer Treatment
10. PSA Can Predicts The Treatment Response In Advanced Prostate Cancer
11. Rapid Aging of Arteries In People With Advanced Heart Disease
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/23/2017)... ... September 23, 2017 , ... Silicon Valley Hair Institute, the leading ... new blog post focused on the ARTAS® hair transplant system and the younger demographic. ... the latest, most technologically sophisticated methods of hair restoration. , “It can be emotionally ...
(Date:9/22/2017)... Plano, TX (PRWEB) , ... September 22, 2017 , ... ... created to strengthen the communities they serve as part of the nationally recognized ‘Agents ... by working closely with nonprofit organizations and community leaders to seek out those who ...
(Date:9/22/2017)... ... 22, 2017 , ... Happy Living’s mission - to improve the health and ... the entertaining and delicious worlds of theatre and wines. , After watching Scott ... to turn his play into a book. The Greener The Grass ( https://www.happyliving.com/books/the-greener-the-grass ) ...
(Date:9/22/2017)... (PRWEB) , ... September 22, 2017 , ... ... host Rob Lowe, explores the world of Alzheimer’s. Alzheimer’s is a disease estimated ... disease. This according to information published by the Alzheimer’s Association, a leading voice ...
(Date:9/22/2017)... ... September 22, 2017 , ... Egg freezing and embryo freezing ... have a slight statistical advantage for live births, frozen eggs offer many advantages, ... women undergoing medical treatment or who are concerned about the decline of their ...
Breaking Medicine News(10 mins):
(Date:9/22/2017)... 22, 2017 AVACEN Medical (AVACEN) announced that ... successfully helping those with the widespread pain associated with ... Amanda in Essex, England commented, ... hair, experiencing no sleep at all, tremendous pain, with ... cannot recommend [the AVACEN 100] enough, how this has ...
(Date:9/18/2017)... R.I. , Sept. 18, 2017 /PRNewswire/ ... the fields of bioinformatics and immune engineering, ... a protective avian influenza A (H7N9) vaccine. ... distantly related to seasonal influenza and presents ... rely on prior exposure to be effective. ...
(Date:9/12/2017)... , Sept. 12, 2017  ValGenesis Inc., ... Solutions (VLMS), is pleased to announce the appointment ... member of its Board of Directors and Chairman ... VLMS enables life science companies to manage their ... use of paper in this process. Furthermore, ValGenesis ...
Breaking Medicine Technology: