Navigation Links
Adult antiviral drug effective in suppressing hepatitis B in teens
Date:12/5/2012

A recent clinical trial found that the adult antiviral drug, tenofovir disoproxil fumarate (tenofovir DF), is safe and effective in treating adolescents with hepatitis B virus (HBV). Trial results published in the December issue of Hepatology, a journal of the American Association for the Study of Liver Diseases (AASLD), show that tenofovir DF suppressed HBV in 89% of pediatric participants.

Chronic HBV is a major health burden that studies estimate affects 350 million people worldwide, with 600,000 deaths attributed to this chronic disease. The Centers for Disease Control and Prevention (CDC) estimate that more than one million Americans have chronic HBV, with most patients infected during childhood. Medical evidence suggests that 90% of patients infected as infants, and up to 50% infected between one and four years of age develop chronic HBV; 25% of adults who become chronically infected in childhood develop cirrhosis or liver cancer.

"Children chronically infected with HBV are at great risk of developing severe liver disease and possible death due to complications from the disease," said Dr. Karen Murray, Chief of the Division of Gastroenterology and Hepatology at Seattle Children's Hospital in Washington and lead researcher of the clinical trial. "Tenofovir DF is highly effective in treating adults with chronic HBV and our trial evaluated safety and efficacy of the drug in adolescents."

This double-blind, placebo-controlled trial was conducted in 101 adolescents aged 12 to 17 years. Participants were randomized with 52 receiving a daily 300 mg dose of tenofovir DF and 54 taking a placebo for 72 weeks. A virologic responseability of the antiviral medication to suppress the virus in participantswas the main outcome of this clinical trial. At the onset of the trial 91% of participants tested positive for the hepatitis B e-antigen and 85% received prior HBV therapy.

Researchers observed a virologic response in 89%
'/>"/>

Contact: Dawn Peters
sciencenewsroom@wiley.com
781-388-8408
Wiley
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Infection Might Raise Blood Clot Risk for Older Adults: Study
2. EKG Heart Test May Predict Risk in Older Adults
3. Unique approach needed to accurately assess health of young adult cancer survivors
4. Out-of-hand tree nut consumption associated with better diet quality in children and adults
5. Symptomatic behaviour in childhood strongly predicts psychiatric treatment as a young adult
6. Gay Adults Rejected by Parents Have Worse Health, Study Finds
7. Feelings of immaturity accompany alcohol misuse into adulthood; discovery could improve treatments
8. Callahan honored for improving older adults health in their doctors offices
9. Anti-tobacco TV ads help adults stop smoking, study finds
10. Childhood Obesity May Raise Odds of Adult Liver Cancer
11. Better health in adulthood starts with early prevention in childhood
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... 2014 Recently, iFitDress.com, a leading online ... has released its new collection of evening dresses ... has announced that all these beautiful items are provided ... of the special offer is July 22. , ... pay close attention to customer satisfaction. On the company’s ...
(Date:7/11/2014)... H.E.A.R Me Out Listens to Needs ... week to provide comprehensive information and services available to ... million Coloradoans with hearing loss, this organization is the ... of the local and state resources that aims to ... , H.E.A.R. Me Out and its website was founded ...
(Date:7/11/2014)... Los Angeles dental implant expert ... and full mouth implants to replace missing teeth. Both ... dental implants from other tooth replacements: They replace the ... alone prevents the long-term complications of missing teeth, but ... comfort, appearance and systemic health. Mini implants broaden candidacy ...
(Date:7/11/2014)... 2014 Having experienced mental illness from the ... mental hospital staff, Roger Grainger gives readers an intimate look ... new book, “You Never Get Out.” , According to the ... Kingdom will experience some kind of mental health problem in ... to take a look at the way mental illness is ...
(Date:7/11/2014)... HealthDay Reporter FRIDAY, July 11, ... who can,t cough, sneeze or laugh without losing bladder ... cells to regenerate weakened urethra muscles. In a ... cells isolated from patients, own fat tissue improved or ... Stress incontinence affects about twice as many ...
Breaking Medicine News(10 mins):Health News:Worldwide Chic Ladies Can Buy Cheap Evening Dresses at iFitDress.com 2Health News:H.E.A.R Me Out Listens to Needs of Hearing Impaired 2Health News:H.E.A.R Me Out Listens to Needs of Hearing Impaired 3Health News:Dental Implant Dentist, Kevin Sands DDS, Now Uses Mini and Full Mouth Implants to Replace Missing Teeth 2Health News:Psychiatric Hospital Patient and Registered Psychologist Explores Mental Health and Therapy in New Book "You Never Get Out" 2Health News:Stem Cells May Ease Urinary Incontinence, Study Says 2Health News:Stem Cells May Ease Urinary Incontinence, Study Says 3
... . , Scientists of the Center for Applied ... discovered the molecular mechanism responsible for the effectiveness of ... two substances in order to produce an effect that ... involved the role played by the AE2 protein when ...
... an early indicator of kidney dysfunction in adults may ... researchers have found. , Microalbuminuria, excessive amounts of albumin ... says Dr. Gregory Harshfield, director of the Medical College ... few studies that have looked at adolescent patients have ...
... Marini Skin Research,Inc. (JMSR; http://www.janmarini.com ) today ... new technology that addresses,common female transitional issues such ... and wrinkles, coarse skin texture and discoloration., ... acne,breakouts while dramatically improving the appearance of follicle ...
... Unique Skills Training Where Patients, Replicate Real-World Challenges in ... ... Personal Support, LOMA LINDA, Calif., Feb. 27 ... in physical,rehabilitation for survivors of stroke, fractures, amputations, brain,injuries, neurological ...
... The Alzheimer,s Foundation,of America (AFA) recently awarded grants ... that will enable them to,develop or enhance educational ... by Alzheimer,s disease and related dementias, and,their families., ... fund a variety of programs,including support services for ...
... Veterans a Sense of Purpose, WASHINGTON, Feb. 27 ... injured during Operation Iraqi,Freedom and Operation Enduring Freedom (OIF/OEF), ... Veterans Winter Sports Clinic in,Snowmass Village, March 30 - ... the physical, social, and emotional,well-being of the veterans who ...
Cached Medicine News:Health News:Cause of effectiveness discovered for a cirrhosis treatment useful in 40 percent of patients 2Health News:Urine protein may be present before hypertension diagnosis in at-risk adolescents 2Health News:Jan Marini Skin Research Introduces Age Intervention(R) Transitions - a New Frontier in Skin Care 2Health News:Loma Linda University Medical Center Celebrates Groundbreaking on Inland Empire's Most Comprehensive Rehabilitation Center 2Health News:Loma Linda University Medical Center Celebrates Groundbreaking on Inland Empire's Most Comprehensive Rehabilitation Center 3Health News:Alzheimer's Foundation of America Awards Grants to Local Groups Nationwide 2Health News:World's Largest Disabled Ski Clinic at Snowmass, Colo. 2
(Date:7/10/2014)... , July 10, 2014  Valeant Pharmaceuticals International, Inc. ... announced it has completed the sale to Galderma of ... owned or held by Valeant for $1.4 billion in ... S.A, which recently completed its acquisition of Galderma. ... of our products to a company that is firmly ...
(Date:7/10/2014)... Decision Resources Group finds that over half ... and Drug Administration,s (FDA) approval of Vifor Fresenius Medical ... approved by the FDA in November 2013 for the ... on dialysis. Other key findings from the ... : , Bundling: ...
(Date:1/15/2014)... As health officials across the Midwest warn against the ... Michigan will offer free diagnostic testing ... pharmacists to administer tests and, in some cases, fill the ... in the study. The Grand Rapids, ...
Breaking Medicine Technology:Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 2Half of Surveyed Nephrologists Report Moderate Familiarity with Velphoro, Which Received FDA Approval Late Last Year for the Treatment of Hyperphosphatemia in Dialysis 3Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 2Meijer Pharmacy Offers Free Flu, Strep Testing as Influenza Cases Rise Across the Midwest 3
... 10 Jefferson Radiology has acquired two Medical ... medical epicenter in north central Connecticut, and in ... expertise available at nine outpatient locations in the ... services at Hartford Hospital, Connecticut Children,s Medical Center, ...
... Ariz., Nov. 10 A recent national survey of 505 ... is important for a patient to seek treatment early to ... And 75 percent of pharmacists say most patients should purchase ... of symptoms, while only 26 percent of their patients take ...
Cached Medicine Technology:Jefferson Radiology Acquires Two Medical Imaging Center Offices 2Pharmacists Report Patients do not Treat Cold and Flu Symptoms Early Enough, New Survey Shows 2Pharmacists Report Patients do not Treat Cold and Flu Symptoms Early Enough, New Survey Shows 3
VascoTip is a unipolar tined permanent pacing lead. Due to advanced technology, VascoTip 9/60 M is compatible to all pacemaker-cavities with the size of IS-1 (3.2 mm), 5 mm, 6 mm....
VascoTip is a unipolar tined permanent pacing lead. Due to advanced technology, VascoTip 9/60 M is compatible to all pacemaker-cavities with the size of IS-1 (3.2 mm), 5 mm, 6 mm....
VascoTip is a unipolar tined permanent pacing lead. Due to advanced technology, VascoTip 9/60 M is compatible to all pacemaker-cavities with the size of IS-1 (3.2 mm), 5 mm, 6 mm....
VascoTip is a unipolar tined permanent pacing lead. Due to advanced technology, VascoTip 9/60 M is compatible to all pacemaker-cavities with the size of IS-1 (3.2 mm), 5 mm, 6 mm....
Medicine Products: