Navigation Links
Adenotonsillectomy may help resolve obstructive sleep apnea in children with Prader-Willi syndrome
Date:11/20/2012

Children with Prader-Willi syndrome may receive relief from sleep disorders after undergoing an adenotonsillectomy, suggests a new study from Nationwide Children's Hospital published in the November print issue of the Archives of Otolaryngology-Head and Neck Surgery.

"Patients with Prader-Willi syndrome are at risk for sleep disordered breathing as growth hormone commonly used to treat their condition can cause the tonsils and adenoids to enlarge," said the study's lead author Kris Jatana, MD, FAAP, with Otolaryngology Head & Neck Surgery at Nationwide Children's.

"Growth hormone in a low dose is extremely beneficial to most patients with Prader-Willi syndrome," said David Repaske, PhD, MD co-director of the Prader Willi Center and chief of Endocrinology, Metabolism & Diabetes at Nationwide Children's. "This beneficial effect has nothing to do with growth, but rather, it markedly improves patients' ability to eat, sit, stand, walk or run depending on their developmental stage and due to a positive effect on their low muscle tone."

At Nationwide Children's, Prader-Willi patients undergo an annual sleep study and are evaluated for potential adenotonsillectomy if obstructive apnea events are present. To evaluate the efficacy of adenotonsillectomy in the treatment of sleep apnea in Prader-Willi syndrome, investigators at Nationwide Children's performed a retrospective chart review. Thirteen patients met the study criteria and were categorized based on severe, moderate or mild apnea/hypopnea indexes and obstructive hypoxia.

Findings showed that 89 percent of the patients with mild-to-moderate obstructive sleep apnea or obstructive hypoventilation normalized after receiving adenotonsillectomy. Of the four children with severe obstructive sleep apnea, two normalized after surgery and two continued to have severe apneas.

"These findings suggest that adenotonsillectomy is effective in most children with Prader-Willi syndrome who demonstrate mild to moderate obstructive sleep apnea, but may not be curative in children with severe forms of the condition," said Dr. Jatana, also a faculty member at The Ohio State University College of Medicine.

Dr. Jatana and his team of investigators stress that patients should receive a repeat sleep study six-to-eight weeks postoperatively since an increase in central apneas can occur in some Prader-Willi children after upper airway surgical intervention.


'/>"/>

Contact: Erin Pope
Erin.Pope@NationwideChildrens.org
614-355-0495
Nationwide Children's Hospital
Source:Eurekalert

Related medicine news :

1. Guidelines Issued to Resolve Temporary Facial Paralysis
2. Non-invasive treatment for children with obstructive sleep apnea suggested by Ben-Gurion University study
3. Rhode Island Hospital study: Bariatric patients with obstructive sleep apnea fail to show symptoms
4. Obstructive sleep apnea is associated with diabetic peripheral neuropathy
5. Many seniors sleep habits are similar to those of young adults, study suggests
6. Sleeping Pill Linked to Hospital Falls, Researchers Say
7. Inpatient sleeping drug quadrupled fall risk
8. Mechanism of breathing muscle paralysis in dreaming sleep identified
9. Energy Drinks Disrupting U.S. Soldiers Sleep: CDC
10. Losing Weight May Improve Sleep Quality
11. Sleep problems cost billions
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/17/2017)... BEAVER CREEK, CO (PRWEB) , ... February 17, 2017 , ... ... the second annual International Healing NET Foundation Summit from February 21 - 23 in ... Healing NET Foundation (HNF). This marks the Summit’s second year in Beaver Creek, hosting ...
(Date:2/17/2017)... ... February 17, 2017 , ... Dillon Ruxton Insurance, a Florida-based ... owners in the greater Fort Lauderdale metropolitan region, is embarking on a cooperative ... 30 years, LifeNet 4 Families has provided a broad range of food provision ...
(Date:2/16/2017)... ... February 17, 2017 , ... For some cancer survivors, ... final treatments. Physician researchers at The Marcus Institute of Integrative Health at ... efficacy in reducing symptoms of traumatic stress in cancer patients and published ...
(Date:2/16/2017)... ... February 17, 2017 , ... ... financial planning services to families and entrepreneurs in the Birmingham area, is announcing ... mother who needs assistance with her medically challenged son, Anius. , Anius is ...
(Date:2/16/2017)... ... 16, 2017 , ... Doctors on Liens is proud to ... network through his work at BKP Chiropractic in Lancaster . After ... from Canada’s prestigious International Baccalaureate Program, Dr. Raj went on to open successful ...
Breaking Medicine News(10 mins):
(Date:2/17/2017)... -- Research and Markets has announced the addition of the ... their offering. ... separate comprehensive analytics for the US, Canada , ... , and Rest of World. Annual estimates and forecasts are provided ... provided for these markets. Market data and analytics are derived from primary ...
(Date:2/17/2017)... Feb. 17, 2017  Featuring new ... at the  2017 HIMSS Conference & Exhibition (HIMSS17 ),  ... a global leader in health ... of population health management, acute healthcare ... integrated in a highly secure, cloud-based ...
(Date:2/16/2017)... , Feb. 16, 2017 Research and ... for Emerging Medical Device Technologies" report to their offering. ... ... open procedures, general instruments, non-drug coated implantables, large endoscopes, needle ... in use over the last two to three decades for ...
Breaking Medicine Technology: