Navigation Links
Adding radiation to hormone therapy for prostate cancer treatment will increase survival chances
Date:10/25/2010

Prostate cancer patients who are treated with a combination of hormone therapy and radiation have a substantially improved chance of survival compared to patients who do not receive radiation, according to interim results of the largest randomized study of its kind presented at the plenary session, November 1, 2010, at the 52nd Annual Meeting of the American Society for Radiation Oncology (ASTRO).

From 1995 to 2005, 1,205 men with high-risk prostate cancer in the United States, the United Kingdom and Canada were randomly selected to receive hormone therapy alone or a combination of hormone therapy and radiation treatment and were followed for at least six years on average. The study was jointly conducted by the National Cancer Institute of Canada, the United Kingdom Medical Research Council and the Southwest Oncology Group in the United States.

Interim results of the study show that the addition of radiation therapy significantly decreased the risk of death among these patients. There were also no increased long-term side effects associated with the treatment. The independent data monitoring committee recommended the release of these results for presentation in view of their importance. The final analysis will be released after further follow-up with the patient group.

"If the figures from the interim analysis are similar to the final analysis, we would expect a 43 percent reduction in the chances of death from prostate cancer in men with this regimen," Malcolm Mason, M.D., lead author of the study and a radiation oncologist at Cardiff University in Cardiff, Wales, United Kingdom, said. "This would translate into a reduction in the chances of deaths from prostate cancer in many thousands of men worldwide."

There is much variation in the treatment for men with localized, high-risk prostate cancer and it is a hotly debated topic. While the number of men treated with combined hormone and radiation therapy has increased in recent years, there are still many patients treated with hormone therapy alone.

This multicenter, randomized trial examined the effects of external beam radiation treatment added to lifelong androgen deprivation therapy for prostate cancer patients who had a high risk of the cancer returning after treatment.

During external beam radiation therapy, radiation beams are directed through the skin to the prostate and the immediate surroundings to destroy the main tumor and any nearby cancer cells. The treatments are outpatient and generally painless, much like receiving an X-ray. Side effects most often reported are mild bowel and bladder problems. Patients typically do not experience hair loss or nausea like with some other treatments.

Androgen deprivation therapy is hormone therapy used to treat prostate cancer by lowering the level of male hormones (androgens) to shrink the prostate or slow down the growth of prostate cancer.

"This study is practice changing as it highlights the importance of radiation in the treatment of high-risk prostate cancer patients and clearly demonstrates its benefits," Dr. Mason said. "It shows that the standard treatment for these patients should now be hormone therapy plus radiation."


'/>"/>

Contact: Beth Bukata
bethb@astro.org
703-839-7332
American Society for Radiation Oncology
Source:Eurekalert

Related medicine news :

1. Adding topotecan to standard treatment for ovarian cancer does not improve progression-free survival
2. Adding Recess to the Workday Gains Backers
3. Ellsworth Adhesives Is Adding PRC Rapid Seal Product Line Offering
4. Adding Surgery to Meds May Improve Life With Parkinsons
5. Alzheimers Association Applauds Social Security Administration for Adding Early-Onset Alzheimers to Its Compassionate Allowances Initiative
6. Highly targeted radiation technique minimizes side effects of prostate cancer treatment
7. Newer, more intense chemotherapy with less radiation not more effective against Hodgkins lymphoma
8. Chemotherapy plus radiation prevents bladder cancer recurrences
9. Radiation therapy improves painful condition associated with multiple sclerosis
10. Radiation Before Surgery May Prevent Return of Rectal Cancer
11. Demand for Radiation Therapy Predicted to Exceed Supply
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/18/2017)... ... January 18, 2017 , ... PrideStaff, a national, ... Franchise Development, Paula Turner Pizarro, was recently featured on Fox Business Network's Worldwide ... of top business leaders from across the globe, provides viewers an opportunity to ...
(Date:1/18/2017)... (PRWEB) , ... January 18, 2017 , ... ... offering asset protection and financial planning services to families and business owners in ... event aimed at supporting children with developmental disabilities. , The Lakemary Center is ...
(Date:1/18/2017)... ... , ... Dr. Farhan Qureshi is an esteemed dentist who offers a full ... has two convenient office locations in Alexandria and Arlington, Virginia. Recently, Find Local Dentists ... area. This award confirms the fact that Dr. Qureshi’s patients have left highly ...
(Date:1/18/2017)... , ... January 18, 2017 , ... ... company, launched a new website for its Center for Biosimilars, announced Michael J. ... the latest developments in the field of biosimilars through thought leader interaction in, ...
(Date:1/18/2017)... ... January 18, 2017 , ... ... Active Brake Technology (ABT), an innovative braking system that allows skaters of all ... addresses one of the biggest concerns of beginner and intermediate skaters – learning ...
Breaking Medicine News(10 mins):
(Date:1/18/2017)... -- After the recent election cycle, it is ... both for medical and recreational purposes are shifting. The evidence ... use of cannabis, but the focus is coming from both ... the North American legal cannabis market posted $6.7 billion in ... research projects sales will grow at a compound annual growth ...
(Date:1/18/2017)... TOKYO , Jan. 18, 2017  Astellas ... , "Astellas" ) today announced its participation in ... access to non-communicable disease (NCD) prevention, diagnostics and ... with 21 other leading pharmaceutical companies and in ... Union for International Cancer Control (UICC), Astellas will ...
(Date:1/17/2017)... , Jan. 17, 2017 Precision medicine ... for the treatment of disease. The approach allows ... to a therapy. The approach studies the individual ... lifestyle and environment. In January 2015, Precision Medicine ... to all diseases with more than one million ...
Breaking Medicine Technology: