Navigation Links
Adding Chemo to Tamoxifen Helps Some Breast Cancer Patients
Date:12/10/2009

n's team assigned 381 women to tamoxifen alone, 587 to chemotherapy alone and 590 to both, with some receiving tamoxifen and chemo together and some in a sequential manner.

Tamoxifen was taken daily for five years. The chemo regimen used is called CAF, for "cyclophosphamide, Adriamycin and 5-fluorouracil."

In all, after accounting for study dropouts, 1,460 women received treatment.

The combined treatments of chemo plus tamoxifen increased the women's disease-free survival by 24 percent, Albain found. When her team looked at which delivery protocol worked best -- simultaneous tamoxifen and chemotherapy or chemo followed by tamoxifen -- the sequential approach was found to be better, giving slightly better disease-free survival.

Ten-year disease-free survival estimates were 57 percent for the combination group and 48 percent for the tamoxifen-only group, the researchers found.

However, women receiving chemo were more likely to have drops in white blood cells, important for fighting infections, the team noted. And they were also more prone to blood clots, congestive heart failure and other complications.

In a second study, Albain's team analyzed whether a gene test, called Oncotype DX, could predict which women would benefit from chemotherapy. Genomic Health, which makes the test, helped fund the study, along with the U.S. National Cancer Institute.

The test, which Albain said is already widely used, is done on the tumor itself. "This puts 21 genes together and comes up with a score," she said. The score -- low, intermediate, high -- predicts the risk of recurrence over 10 years if a woman used tamoxifen alone.

When the researchers performed the test on 367 specimens, they found a low score identified those women who may not need the chemo, despite the fact that they have cancer that spread to lymph nodes.

"This is a positive study, there's no question," said Dr. Joanne Mortimer
'/>"/>

Copyright©2009 ScoutNews,LLC.
All rights reserved

Page: 1 2 3

Related medicine news :

1. Adding Proton Therapy Boost to X-Ray Radiation Therapy Reduces Prostate Cancer Recurrences
2. Adding Chemo Helps Head, Neck Cancer Patients
3. Adding tools against breast tumors
4. Adding Drug Doesnt Help Control Blood Pressure
5. CutisPharma Launches New Prescription Mouthwash Kit Adding to Product Line
6. Adding a Stent May Help Resolve Brain Aneurysm
7. Dakim BrainFitness Now Used in 286 Senior Living Communities, Adding 136 Sites in 12 Months for Dementia-Fighting System
8. Hospital Improves Patient Experience by Adding Email and Web Access in Patient Rooms With Virtual Linux Desktops
9. Contracts adding legal twist to family health care
10. Takeda to Acquire IDM Pharma, Adding MEPACT(R) (Mifamurtide), the First Treatment Approved for Osteosarcoma in More Than 20 Years, to Its Oncology Franchise
11. CoolSign 4.3 Released Adding New Features for Digital Signage Networks
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/12/2014)... July 12, 2014 Utah Valley Entrepreneurial ... startups, with awards being bestowed to companies in revenue, ... outstanding entrepreneur community with recognition for new ideas as ... with incoming revenue. , 25 Under 5 highlights outstanding ... that are under 5 years old. Award recipients were ...
(Date:7/12/2014)... Restore My Vision Today is a new ... couple boasting very impressive credentials on the field of ... as a way to help consumers do without the ... respective patients’ treatments . , In particular, ... of pertinent information relevant to eye care like:, ...
(Date:7/11/2014)... 12, 2014 Recently, MagicQuinceaneraDresses.com, the popular ... new collection of 2014 Quinceanera dresses . The ... want to look fashionable without paying a large amount ... up to 57% off. , The company’s online shop ... get amazing special occasion outfits. In addition to exquisite ...
(Date:7/11/2014)... New York, New York (PRWEB) July 11, 2014 ... ( http://www.transvaginalmeshlawsuithelp.com/ ) , filed against Johnson & ... U.S. courts, Bernstein Liebhard LLP notes that the ... is investigating the company’s marketing of surgical mesh ... stress urinary incontinence. According to a report from ...
(Date:7/11/2014)... from Scientology Churches and Missions are taking ... lectures, forums and conferences, information stands, sports events, and ... , Drug abuse is an international epidemic. According to ... alcohol and illicit drugs costs more than $425 billion ... healthcare. , In the face of statistics such ...
Breaking Medicine News(10 mins):Health News:SquareHook is Recognized for UVEF 25 Businesses Under 5 Years-Watch Out 2Health News:Restore My Vision Today | Groundbreaking Book Reveals How To Restore Your Vision Without The Use of Glasses – Vinamy 2Health News:Restore My Vision Today | Groundbreaking Book Reveals How To Restore Your Vision Without The Use of Glasses – Vinamy 3Health News:Cheap Quinceanera Dresses Now Available At MagicQuinceaneraDresses.com 2Health News:Transvaginal Mesh Lawsuit News: Bernstein Liebhard LLP Notes Report of Texas Probe into Ethicon Pelvic Mesh Marketing 2Health News:Transvaginal Mesh Lawsuit News: Bernstein Liebhard LLP Notes Report of Texas Probe into Ethicon Pelvic Mesh Marketing 3Health News:Transvaginal Mesh Lawsuit News: Bernstein Liebhard LLP Notes Report of Texas Probe into Ethicon Pelvic Mesh Marketing 4Health News:Scientologists Taking Action against Drug Abuse 2Health News:Scientologists Taking Action against Drug Abuse 3
... yet another reason to reduce childhood obesity it may ... of the Journal of Allergy and Clinical Immunology ... of having some kind of allergy, especially to a food. ... Health Sciences (NIEHS) and the National Institute of Allergy and ...
... Healthcare Management Systems, Inc.(R) (HMS) announced today it ... technology provider. HMS has grown throughout the years ... currently develop, sell and support integrated clinical and financial ... decade, HMS has expanded its primary market of community ...
... in the May issue of the Journal of the ... electronic prescribing systems may allow for greater efficiency at hospitals, ... of care. , In an attempt to reduce or ... called for the use of electronic prescribing systems in all ...
... PHILADELPHIA, May 4 Children hospitalized with concussions ... clinician in a follow-up exam before returning to ... at The Children,s Hospital of Philadelphia. Rather than ... trouble signs after the initial treatment, the Children,s ...
... May 4 On Monday, May 4, Andrews ... Center at Fort Worth, will receive the "2009 ... Institute, a national women,s health conference for hospitals/health ... planning professionals. The conference offers profiles of successful ...
... Analytical, based in Ames, IA will reveal the latest results ... system. This instrument rapidly identifies microorganisms in less ... The generated fingerprint when compared to a database of ... strain typing and tracking.Because of its ease of use and ...
Cached Medicine News:Health News:New data analysis shows possible link between childhood obesity and allergies 2Health News:Healthcare Management Systems Celebrates 25 Years 2Health News:Electronic prescribing systems boost efficiency, may lead to improved quality of care 2Health News:Children with Concussions Require Follow-up Care Before Returning to Play, Say Researchers 2Health News:Children with Concussions Require Follow-up Care Before Returning to Play, Say Researchers 3Health News:Andrews Women's Hospital Receives National Recognition At Achieving Success In Women's Health Conference 2Health News:Advanced Analytical Reveals New Platform for Rapid Genotypic Identification of Microorganisms at ASM 2009 2
(Date:7/10/2014)... CARLSBAD, Calif. , July 10, 2014 /PRNewswire/ ... products and services, has launched the FreeRunner™ knee ... runners, who suffer from patella mal-tracking return to ... anatomy differently than other braces, providing support when ... move normally when they don,t. Patellofemoral ...
(Date:7/10/2014)...  RESMED INC. (NYSE: RMD ) today announced ... ended June 30, 2014 results on Thursday, July 31, 2014, ... release with ResMed,s results will be issued after 1:00 p.m. ... to discuss operating results and future outlook. The ... Pacific Time and the live webcast of the call can ...
(Date:7/10/2014)... , July 10, 2014  BC Technical, the ... MiE America , Inc., a leading provider of ... into a long-term agreement naming BC Technical as the ... MiE and BC Technical announced today ... to establish BC Technical as the service and systems ...
Breaking Medicine Technology:Breg Introduces Knee Brace to Help Runners with Patellofemoral Pain Syndrome 2ResMed To Announce Fourth Quarter And Fiscal Year-End 2014 Results 2BC Technical Partners With MiE America To Be Authorized Provider Of Systems & Service 2
... Sept. 1, 2011 Hill-Rom Holdings, Inc., (NYSE: ... management presentation at the Morgan Stanley Global Healthcare Conference ... 8:35 a.m. ET. You are invited to ... at http://ir.hill-rom.com/events.cfm or access it directly at ...
... makers of the ACCU-CHEK® portfolio of diabetes management products ... Infusion Site Awareness Week, Aug. 29-Sept. 4, a week-long ... management for the 400,000 people in the United States ... "The inaugural Infusion Site Awareness Week, which ...
Cached Medicine Technology:Roche Diabetes Care Celebrates Second Annual Infusion Site Awareness Week, Aug. 29-Sept. 4 2Roche Diabetes Care Celebrates Second Annual Infusion Site Awareness Week, Aug. 29-Sept. 4 3
... X-22 Series is up to 10 inches/ 25 cm ... 11 rotors, the Allegra X-22 Series is the space-saving ... Only 18 inches / 46 cm wide • 11 ... 3 different ways to Spin 1.5 mL & ...
... centrifuges offer high-volume versatility along with a ... them ideal for a wide variety of ... Four- or six-place sealed swinging bucket rotor, ... offered , Lare capacity (4 x 750 ...
... performance centrifuge designed to accommodate over 55 ... refrigerated for heat labile samples. Incorporating the ... capability with automatic quick cooling from 22 ... min, no maintenance brushless motor, low pitch ...
Inquire...
Medicine Products: