Navigation Links
Addex highlights strength of allosteric modulation technology platform
Date:11/12/2010

Geneva, Switzerland, 12 November 2010 Allosteric modulation company Addex Pharmaceuticals (SIX:ADXN) announced today that data on a total of nine therapeutic programs will be presented during Society for Neuroscience 2010 (November 13-17, San Diego, USA), highlighting the strength of its allosteric modulation technology platform. The data being presented cover multiple receptor types and therapeutic areas, including Parkinson's disease, schizophrenia, anxiety, Alzheimer's disease and depression.

"The data generated by Addex and our partners, Ortho-McNeil-Janssen and Merck & Co., being presented at the Society for Neuroscience 2010 conference illustrate the power of our allosteric modulation product generating engine. Although the targets we are addressing have been pursued for many years with standard discovery technologies, most have proven elusive," explained Dr. Vincent Mutel, CEO of Addex. "Our technology is allowing us to bring a new kind of chemistry to industrial drug discovery efforts and thereby improve discovery productivity, a key bottleneck hindering the pharmaceutical industry. Beyond our presentations at Society for Neuroscience this year, we have recently demonstrated our ability to expand our discovery technology beyond GPCRs, like glutamate receptors, to cover other types of cell surface receptors, such as cytokine receptors, including TNF receptors. In addition to advancing our own molecules, we will look to sign multiple collaborative partnerships to realize the potential of our platform."

Small molecule allosteric modulators represent an unexploited kind of chemistry which is different from the traditional small molecule drugs. Orally available allosteric modulators can offer multiple competitive advantages over classical drugs. Most importantly, they can be more specific for their target receptor in the body, while at the same time, offering more precise control over receptor function. They can do this because they bind t
'/>"/>

Contact: Mike Sinclair
msinclair@halsin.com
44-207-318-2955
Halsin Partners
Source:Eurekalert

Page: 1 2 3

Related medicine news :

1. Mayo Clinic Proceedings: November highlights
2. UCI non-small cell lung cancer study highlights advances in targeted drug therapy
3. New study highlights sexual behavior, condom use by US individuals ages 14 to 94
4. 2010 AAO-HNSF new research daily highlights: Wednesday, Sept. 29, 2010
5. Medicinal cannabis review highlights dilemmas facing health care professionals
6. AWARD Fellowship highlights critical role of African women in agricultural research
7. Trainee publication highlights success of US-China agricultural injury research training project
8. Patient safety highlights American Association of Physicists in Medicine
9. Preliminary highlights of the AAPM 52nd Annual Meeting, Philadelphia, Pa., July 18-22, 2010
10. STDTestExpress Highlights National HIV Testing Day with Free HIV Testing
11. Survey highlights major Canada-US differences in people in middle age
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/4/2015)... Ticket Down is a reputable source for authentic Paul ... South Carolina. Fans of Paul McCartney have to be ... originally kicked off in 2013. The most visited continent of ... performer recently announced that he would be adding additional dates ... in Charlottesville, VA at John Paul Jones Arena on ...
(Date:5/4/2015)... 2015 CCL, a top-ranked, global provider ... program to other leadership development consultancies. “The CCL ... and successful practitioners, expanding our capacity to drive results ... John R. Ryan, CCL President and CEO. , As ... Partner Network , it will schedule a one-on-one conference ...
(Date:5/4/2015)... May 04, 2015 San Diego ... ceremony at their brand new, 13,700 square foot facility ... new building will not only provide fertility treatment and ... also offer community and educational events to a number ... is located next door to their current Carmel Valley/Del ...
(Date:5/4/2015)... (PRWEB) May 04, 2015 Dr. Benjamin ... Georgia proudly offers the latest non-surgical double-chin eliminator. ... facial plastic surgeon in Atlanta to offer Kybella ... to be injected specifically under the chin, promising to ... , Before Kybella, patients who sought immediate solutions for ...
(Date:5/4/2015)... 04, 2015 Unlike some camps, the Nike Middle ... The goal is to educate first and train second, with ... ensures that the young runners are building the knowledge base needed ... of the topics covered include Effort Based Training, Running Heroes, Running ... to be? This is not a camp where kids come ...
Breaking Medicine News(10 mins):Health News:Paul McCartney Tickets at Colonial Life Arena in Columbia, SC: Ticket Down Slashes Paul McCartney Ticket Prices in Columbia, South Carolina at Colonial Life Arena 2Health News:The Center for Creative Leadership Is Partnering with Lead Star to Create the CCL Partner Network 2Health News:San Diego Fertility Center Hosted a Ribbon Cutting Ceremony at Its New, Expanded Facility 2Health News:San Diego Fertility Center Hosted a Ribbon Cutting Ceremony at Its New, Expanded Facility 3Health News:Facial Plastic Surgeon First in Atlanta To Offer Kybella Treatments To Reduce Chin Fat 2Health News:US Sports Camps and Select Nike Running Camps Offer Programs for Middle School Runners 2
... Abramson, MD, professor of medicine and director of ... hosted a webinar with colleagues from the medical ... together, bench, bedside and the blogosphere to discuss ... RA. The webinar can be viewed at: , ...
... FRIDAY, June 10 (HealthDay News) -- Women are more likely ... a new study contends. A nuclear stress test, also ... blood flow to the heart muscle at rest and during ... heart disease, but it,s expensive and exposes people to radiation. ...
... -- Preschool children with symptoms of attention-deficit/hyperactivity disorder (ADHD) ... an important role in cognitive and motor control, new ... develop ways to treat the common behavioral disorder in ... Kennedy Krieger Institute in Baltimore. In the study, ...
... HealthDay Reporter , THURSDAY, June 9 (HealthDay News) -- The ... new support from a study in mice -- and the ... control weight gain. It,s always a leap to extrapolate ... does open up interesting possibilities. "Humans have basically the ...
... Respirology issues a serious warning of massive ... Dr Ken Takahashi, Acting Director of the WHO Collaborating ... important data on asbestos use in 47 Asian countries ... the highest age-adjusted mortality rates in Asia. This study ...
... - Negative family attitudes can have an adverse effect ... study. Researchers found that although family members, ... mentally ill, they can also be the source of ... recovery. "Negative attitudes of family members have the ...
Cached Medicine News:Health News:NYU Langone rheumatologists share insight with online RA community 2Health News:Women May Be Getting Unneeded Heart Imaging Tests 2Health News:Brain Scan Spots Differences in Tots With ADHD Symptoms 2Health News:Mouse Study Reveals How Smoking Helps Keep People Thin 2Health News:Deaths and major morbidity from asbestos-related diseases in Asia likely to surge in next 20 years 2Health News:Mothers Play Important Role in Recovery From Mental Illness 2
(Date:5/4/2015)... Calif. , May 4, 2015  Impax Laboratories, ... filled two key executive leadership roles, appointing  Donna M. ... Deborah M. Penza , as Senior Vice President, Chief ... report to Impax,s President and Chief Executive Officer, ... Donna and Deborah have joined the Impax team," said ...
(Date:5/4/2015)... -- Bayer HealthCare (Bayer) has entered into an exclusive ... ) on ISIS-FXI Rx, an antisense investigational drug ... the agreement Bayer will further develop and commercialize ISIS-FXI ... As part of the clinical development program, Bayer plans ... in an appropriate patient community. "Bayer is ...
(Date:5/4/2015)... ANGELES , May 4, 2015  CytRx ... and development company specializing in oncology, today announced ... 1b aldoxorubicin combination studies pairing aldoxorubicin with either ... of gemcitabine or ifosfamide with escalating doses of ... and even at the lowest dose level of ...
Breaking Medicine Technology:Impax Strengthens Leadership Team by Adding New Senior Vice Presidents for Human Resources and Compliance 2Impax Strengthens Leadership Team by Adding New Senior Vice Presidents for Human Resources and Compliance 3Bayer Licenses Investigational ISIS FXI(Rx) from Isis Pharmaceuticals to Develop and Commercialize for the Prevention of Thrombosis 2Bayer Licenses Investigational ISIS FXI(Rx) from Isis Pharmaceuticals to Develop and Commercialize for the Prevention of Thrombosis 3CytRx Reports Aldoxorubicin Demonstrates Both Tumor Shrinkage and Improved Quality of Life in Chemotherapy Resistant Cancers 2CytRx Reports Aldoxorubicin Demonstrates Both Tumor Shrinkage and Improved Quality of Life in Chemotherapy Resistant Cancers 3CytRx Reports Aldoxorubicin Demonstrates Both Tumor Shrinkage and Improved Quality of Life in Chemotherapy Resistant Cancers 4CytRx Reports Aldoxorubicin Demonstrates Both Tumor Shrinkage and Improved Quality of Life in Chemotherapy Resistant Cancers 5CytRx Reports Aldoxorubicin Demonstrates Both Tumor Shrinkage and Improved Quality of Life in Chemotherapy Resistant Cancers 6CytRx Reports Aldoxorubicin Demonstrates Both Tumor Shrinkage and Improved Quality of Life in Chemotherapy Resistant Cancers 7
... ZymoGenetics,Inc. today announced that interim findings were presented ... B-cell chronic,lymphocytic leukemia (B-CLL) at the American Society ... included intravenous,administration of higher doses than had been ... was well-tolerated and biologically,active at all dose levels ...
... Biotechnology,Inc. (OTCBB: CGRB) today announced that positive interim ... prostate cancer drug candidate,CB7630 (abiraterone acetate) was presented ... Meeting, which is currently,taking place in Chicago, Illinois. ... Saturday, June 2nd, as part of the poster,discussion ...
Cached Medicine Technology:ZymoGenetics Reports Results From Atacicept Phase 1b Clinical Trial,in B-Cell Chronic Lymphocytic Leukemia 2ZymoGenetics Reports Results From Atacicept Phase 1b Clinical Trial,in B-Cell Chronic Lymphocytic Leukemia 3Cougar Biotechnology Announces Presentation of Positive CB7630,Clinical Data at ASCO Annual Meeting 2Cougar Biotechnology Announces Presentation of Positive CB7630,Clinical Data at ASCO Annual Meeting 3Cougar Biotechnology Announces Presentation of Positive CB7630,Clinical Data at ASCO Annual Meeting 4Cougar Biotechnology Announces Presentation of Positive CB7630,Clinical Data at ASCO Annual Meeting 5Cougar Biotechnology Announces Presentation of Positive CB7630,Clinical Data at ASCO Annual Meeting 6