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Acute respiratory distress syndrome: Study IDs surgical patients at risk
Date:4/21/2014

ROCHESTER, Minn. Acute respiratory distress syndrome is a leading cause of respiratory failure after surgery. Patients who develop the lung disorder postoperatively are at higher risk of dying in the hospital, and those who survive the syndrome may still bear its physical effects years later. A Mayo Clinic-led study is helping physicians better identify patients most at risk, the first step toward preventing this dangerous and costly surgical complication. They found nine independent risk factors, including sepsis, high-risk aortic vascular surgery, high-risk cardiac surgery, emergency surgery, cirrhosis of the liver, and admission to the hospital from a location other than home, such as a nursing home.

The findings are published in the journal Anesthesiology.

"This is a very common reason for needing an extended course of breathing support after surgery, and approximately 20 to 25 percent of patients who develop the syndrome will die from it," says first author Daryl Kor, M.D., a Mayo Clinic anesthesiologist. "It's well-documented that those who develop this syndrome stay in intensive care longer and in the hospital longer, and the impact of the syndrome can persist for many years."

Prevention of acute respiratory distress syndrome has become a priority for the National Institutes of Health's National Heart, Lung, and Blood Institute, the researchers noted.

To help prevent the condition, physicians first must identify who is most at risk, and that has proved difficult to do with individual patients, the researchers say. They studied 1,562 surgical patients considered at high risk of developing the syndrome, and found:

  • Acute respiratory distress syndrome developed in 117, or 7.5 percent.

  • Nine independent factors are predictors of the syndrome: sepsis; high-risk aortic vascular surgery; high-risk cardiac surgery; emergency surgery; cirrhosis; admission to the hospital unit from a locat
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Contact: Sharon Theimer
newsbureau@mayo.edu
507-284-5005
Mayo Clinic
Source:Eurekalert

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