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Activity Against Drug-Resistant Pathogens is One of the Leading Attributes Influencing Physicians' Antibiotic Selection for the Treatment of Inpatient Community-Acquired Pneumonia
Date:2/24/2009

Future Therapies Modeled After Johnson & Johnson/Basilea's or Forest/Novexel's Drug Could Be Used As First-Line Therapies, According to a New Report from AMR and Decision Resources

MALVERN, Pa. and WALTHAM, Mass., Feb. 24 /PRNewswire/ -- Arlington Medical Resources (AMR) and Decision Resources find that activity against drug-resistant pathogens is one of the leading drug attributes influencing surveyed physicians' antibiotic selection for the treatment of inpatient community-acquired pneumonia. Due to the difficulty of obtaining adequate samples for microbiological testing, physicians rely on empiric therapies that can cover key pathogens, particularly resistant and susceptible strains of Streptococcus pneumoniae. In fact, one of the key trends surveyed physicians foresee in the next five years is to prescribe an empiric therapy that covers methicillin-resistant Staphylococcus aureus (MRSA) for inpatients with community-acquired pneumonia.

The new report entitled Hospital Anti-Infectives Insight Series: Community-Acquired Pneumonia also finds that future therapies modeled after Johnson & Johnson/Basilea's ceftobiprole or Forest/Novexel's ceftaroline could be used as empiric first-line therapies for very severe cases of community-acquired pneumonia requiring admission to the ICU or mechanical ventilation.

"Ceftobiprole and ceftaroline couple broad-spectrum cephalosporin activity with targeted activity against MRSA, offering physicians enhanced pathogen coverage for empiric treatment of community-acquired pneumonia in the hospital setting," stated Lisa Arias, analyst at Decision Resources. "We anticipate that future therapies modeled after these agents will gain substantial usage in the market for the treatment of inpatient community-acquired pneumonia and potentially displace usage of older, generically available cephalosporins, due to their anti-MRSA activity."

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SOURCE Decision Resources
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