Navigation Links
Active Smoking Can Worsen Response to Treatment in Patients With Metastatic Kidney Cancer
Date:12/5/2013

Durham, NC (PRWEB) December 05, 2013

A recent study featured in the latest issue of The Oncologist shows that active smoking greatly diminishes patients’ chances of responding to chemotherapeutic treatment for renal cell carcinoma (RCC). The research team, jointly led by Dr. Michael Carducci from the Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Baltimore, MD and Dr. Daniel Keizman from the Sackler School of Medicine at Tel Aviv University, conducted a retrospective analysis exploring the association of various risk factors for RCC with patient response rate and survival following sunitinib treatment.

RCC is the most common type of malignancy of the kidney and the tenth most common cause of cancer-related death among men in the US. Approximately 30% of patients with RCC present with metastases, and 40% of those treated for a localized tumor eventually show recurrence. Sunitinib, a vascular endothelial growth factor (VEGF)-targeting drug, is widely used as a first-line treatment for this disease; however, its efficacy is limited, and tumors will often progress post treatment.

The researchers utilized data from 278 metastatic RCC patients who had undergone sunitinib treatment at 7 different institutions in the US and Israel and assessed known risk factors for the disease, including smoking, obesity, and diabetes, all of which have been associated with poor therapeutic outcome in various cancers. Concordant with RCC epidemiology, the median age of the participants was 63 and about two-thirds of them were men. While about half of the patients were never smokers, more than 20% were active smokers, and the remainder had some history of smoking. Nearly a quarter of the patients were obese, more than a quarter were diabetic, and more than half of them had hypertension prior to sunitinib treatment.

After a median follow-up period of 55 months, imaging evaluations revealed a complete response in 3% o
'/>"/>

Source: PRWeb
Copyright©2012 Vocus, Inc.
All rights reserved

Page: 1 2 3 4 5

Related medicine news :

1. 62 percent of men and 37 percent of women over the age of 65 are sexually active
2. Gene Signal presents data at ARVO 2012 showing topical aganirsen is active in retinal disease
3. Introducing Screenplay: An interactive childrens waiting room experience
4. Inherited DNA change explains overactive leukemia gene
5. Key to More Active, Slimmer Kids: Friends
6. New anti-inflammatory drugs pinch off reactive oxygen species at the source
7. Parents - not TV - may determine whether kids are active or couch potatoes
8. SingleSource Background Screening Company Calls On Adults To Take Proactive Approach To Stop Child Sexual Abuse
9. Active, Outdoor Teens Are Happier Teens: Study
10. Author, Speaker Richard London Battles Parkinson’s with an Active Lifestyle and the Desire to Give Back
11. Friends Life Care, a Pennsylvania Based Long-Term Care Provider, Launches VigR eMeetinghouse — An Interactive Online Community
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/22/2014)... July 22, 2014 The hair ... are now offering robotic assisted laser therapy and ... solutions for men and women suffering from hair ... they now offer Follicular Unit Extraction (FUE) procedures ... robot. With this new technology, their doctors use ...
(Date:7/21/2014)... to target and kill cancer cells could boost the ... help avoid amputation, a new study reports. , Scientists ... effectiveness of a genetically engineered version of the virus ... of the virus alongside isolated limb perfusion chemotherapy ... or leg as an alternative to amputation was ...
(Date:7/21/2014)... 2014 MillionaireCasket.com, a well-known casket manufacturer from ... caskets to its website. In addition to this, the ... off) for all these brand new items. , MillionaireCasket.com ... great caskets for its current and prospective clients. ... and oak caskets and more. According to the company’s sales ...
(Date:7/21/2014)... CA (PRWEB) July 21, 2014 Cannabis ... four major cannabis events this summer. During these festivals, ... by providing additional information and resources to attendees in ... educate the public on the legitimate and beneficial side ... Cannabis Cup in San Francisco, the Kush Expo in ...
(Date:7/21/2014)... to hate losing. , Unfortunately, it,s also human ... solid strategy and thus increasing your chances of losing ... a Brigham Young University study published this week by ... based on an analysis of two decades of data ... whether coaches adjusted their personnel following games where the ...
Breaking Medicine News(10 mins):Health News:WeGrowHair.com/PAI Medical Group Introduces Robotic Assisted Laser Therapy to Treat Hair Loss 2Health News:Viral therapy could boost limb-saving cancer treatment 2Health News:Viral therapy could boost limb-saving cancer treatment 3Health News:Cheap Maple Caskets Recently Added To China Casket Manufacturer MillionaireCasket.com’s Product Line 2Health News:Cannabis Now Magazine Hits the Marijuana Festival Circuit and Sponsors Two Major Events 2Health News:'Moral victories' might spare you from losing again 2
... alcohol quotient is highly conducive for the cognitive development ... has suggested//. Infact, even moderated alcohol intake during the ... child. ,The study conducted by the University of ... has shown that those children, whose mothers had indulged ...
... Geneva – A nod has been given by the administration in ... research and development//. This is indeed a quantum leap in this ... it will also infuse renewed thrust in the area of drug ... novel methods to source drugs, based on the funding. ...
... some alarming world statistics regarding the use of tobacco amongst ... year olds consume tobacco and its products. , ,These ... World Health Organization's World No Tobacco Day; on May 31st. ... in any form or disguise,'' conveying cigarette smoking in any ...
... that nearly a third of the 32,000 terminations by women ... abortion pill, also known as EMA early medical abortion. ... abortion pill in Britain has reached an all time high ... the number of women, which it treated with EMA, rose ...
... students and junior medical doctors of the Medical College ... have decided to not to run the outpatient departments ... doctors have however promised not to cause any inconvenience ... a ‘parallel OPD’s’ for the benefit of patents. A ...
... much commotion across the world and it has drastically affected the ... increase in demand for chicken// and the sales are slowly picking ... in its recuperation stage. ,Mohamed Al Shafei, director of ... has suffered a great deal in the past with a large ...
Cached Medicine News:Health News:Record Number Of Women Use Abortion Pills 2Health News:Agitating Doctors Call For Two Day Shut Down Of OPD’ 2
(Date:7/21/2014)... York , July 21, 2014 ... published by Transparency Market Research "E-Clinical Solution Software Market- ... 2014 - 2020," the global microfluidic device market was ... expected to grow at a CAGR of 13.8% from ... USD 6,515.3 million in 2020. Browse the ...
(Date:7/21/2014)... , July 21, 2014 UBM Medica US ... a leading online community for primary care clinicians offers ... identify and treat victims of a variety of summer ... are packed with a host of medical menaces: poison ... few. Some of the highlights covered on Consultantlive,s topic ...
(Date:7/21/2014)... LAS VEGAS , July 21, 2014 By ... Division will conduct an online sale of ophthalmic and optical ... Las Vegas -based eyewear specialists American Optical Services LLC. ... and will close in rapid succession, live auction style, ... the various assets being offered will be held July 25 ...
Breaking Medicine Technology:E-Clinical Solution Software Market is expected to reach USD 6,515.3 million in 2020: Transparency Market Research 2E-Clinical Solution Software Market is expected to reach USD 6,515.3 million in 2020: Transparency Market Research 3E-Clinical Solution Software Market is expected to reach USD 6,515.3 million in 2020: Transparency Market Research 4E-Clinical Solution Software Market is expected to reach USD 6,515.3 million in 2020: Transparency Market Research 5ConsultantLive Presents Special Coverage of Summer Scourges 2ConsultantLive Presents Special Coverage of Summer Scourges 3Auction Set For Assets Of National Optical Services Company 2
... OCuSOFT, Inc., an ophthalmic pharmaceutical research, development and ... Ardeo Health, LLC to distribute a novel dry eye ... France, Nova23041. Nova23041 will be marketed and ... MGD™ Ophthalmic Emulsion under a brand license from OCuSOFT, ...
... Fla., June 14, 2011 ANF Group, Inc ... today the completion of the 170,000-square-foot Joe DiMaggio Children,s ... Broward County. (Photo: http://photos.prnewswire.com/prnh/20110614/FL18288 ... new central energy plant is designed to earn Gold ...
Cached Medicine Technology:Dry Eye Therapy Utilizing Cationic Novasorb® Technology Available Soon From OCuSOFT® 2Dry Eye Therapy Utilizing Cationic Novasorb® Technology Available Soon From OCuSOFT® 3ANF Group, Inc. Completes New Joe DiMaggio Children's Hospital 2
0.5X1.5mm Tip, Oval Shape; in Titanium....
0.5X2.0mm Tip, Oval Shape; in Titanium....
2.5x8mm Spatula Combined with 8mm Blade; in stainless steel....
0.6mm Tip x10mm Shaft, Straight Shaft, 90 Degree Hook at Tip; overall length 120mm; in Titianium....
Medicine Products: