Navigation Links
Acrylamide Won't Raise Breast Cancer Risk

Fried, baked food compound poses no threat, major study finds

TUESDAY, Aug. 21 (HealthDay News) -- There seems to be little or no link between breast cancer and acrylamide, a substance found in many baked and fried foods, according to the largest epidemiological study on the subject conducted to date.

"The data are accumulating, and it appears that acrylamide in the diet does not appear to be an important breast cancer risk factor," said study author Lorelei Mucci, an assistant professor of medicine at Harvard Medical School and an assistant professor of epidemiology at Harvard School of Public Health in Boston.

"We probably couldn't rule out that eating very high levels of acrylamide is associated with a very, very small increase in risk, but in terms of it being an important public health risk factor for breast cancer I don't think acrylamide is a major risk factor," she said.

Mucci plans to present the finding Tuesday at the American Chemical Society annual meeting, in Boston. The paper is one of 40 exploring various facets of a possible association between acrylamide and cancer.

Acrylamide is classified as a "probable" human carcinogen but only based on earlier animal studies in which the animals were exposed to levels of acrylamide up to 100,000 times higher than that normally consumed through foods.

The substance forms naturally during the cooking process of mostly carbohydrate-rich foods such as potato chips, french fries, breads, cereals and even coffee.

Even though the data on human health has remained unclear, food safety authorities in Europe have started to curb acrylamide in foods.

According to the study authors, about 30 percent of calories consumed among U.S. and European populations contain acrylamide. The average adult consumption is 0.5 micrograms per kilogram of body weight per day. Children consume higher levels.

For the current study, Mucci and her colleagues followed a group of 100,000 U.S. nurses over a 20-year period. Participants periodically answered questionnaires about their dietary habits. This information was used to estimate daily acrylamide intake, which was then correlated with breast cancer incidence.

The result: The incidence of breast cancer among women with a high acrylamide intake was about the same as women with low intakes.

That corresponds with findings from a previous study (also by Mucci) of Swedish women that also showed no association between dietary acrylamide and risk of breast cancer. The largest source of dietary acrylamide in U.S. women is french fries, while in Swedish women it is coffee.

The only other published epidemiological study, conducted in Italy, also found no association.

"At the moment, I don't think there is any clear connection between acrylamide and breast cancer," said Shiuan Chen, director and professor of surgical research at City of Hope Cancer Center in Duarte, Calif.

"I thought the results were gratifying," added Robert Tardiff, president of the Sapphire Group and an advisor to the Food Products Association, both in Washington, D.C.

"Here is an example of a situation which caused a great deal of concern based on laboratory studies, and now we have a reasonably definitive study showing that there's no link between acrylamide consumption and breast cancer. So, that's great," he said.

The association found in animal studies could be explained by the high levels of acrylamide they consumed, or by differences in how acrylamide is metabolized in the body, the experts said.

This is not likely to close the door on research into acrylamide, however.

"The food industry has been spending a lot of time and research on how to avoid acrylamide formation in food, and toxicologists are still very interested in looking at acrylamide," Mucci said. "There's also a new animal study with rats and mice looking at very high levels of acrylamide and cancer risk. There's been concern whether acrylamide could have some impact on hormonal levels, so we would want to look at endometrial and ovarian cancer, because they are hormone-driven."

Tardiff added, "One of the issues that we are working on, and that we think is particularly promising, is that there is significant detoxification of acrylamide quickly [in the human body], so it is no longer available at the levels we found in food. That research will be finished in the next couple of months."

Mucci will also be presenting data at the American Chemical Society meeting on prostate cancer and acrylamide (again, her team found no link).

But cancer is not the only reason to avoid certain foods.

"We want to think about our overall health, and there are a lot of reasons to have a low-fat diet and maintain a healthy weight," Mucci pointed out. "Obesity is a risk factor for so many diseases. Eat a sensible diet, don't eat too much of one thing. If you get a diverse diet, you're probably going to be protecting yourself."

"Environmental exposures have a lot of influence on cancer, including breast cancer, and that includes diet," Chen added. "Diversify your diet. Eating french fries once in a while is probably OK, but not three times a day."

More information

The Joint Institute for Food Safety and Applied Nutrition has information on acrylamide.

SOURCES: Lorelei Mucci, Sc.D., assistant professor, medicine, Harvard Medical School and assistant professor, epidemiology, Harvard School of Public Health, Boston; Shiuan Chen, Ph.D., director and professor, department of surgical research, City of Hope Cancer Center, Duarte, Calif.; Robert Tardiff, Ph.D., president, Sapphire Group, and advisor, Food Products Association, Washington, D.C.; Aug. 21, 2007, presentation, American Chemical Society annual meeting, Boston

Copyright©2007 ScoutNews,LLC.
All rights reserved

Related medicine news :

1. Breast cancer risk not increased by acrylamide
2. Adding Milk to Black Tea Wont Ruin Its Antioxidant Effects
3. Obesity raises IVF miscarriage risk
4. Frequent use of antibiotics raises the risk of carrying resistant infections
5. Heavy Drinking Raises Risk of Liver Cancer
6. Air pollution may raise risk of lung cancer
7. Women are at risk with raised cholesterol
8. Swimming in Chlorinated Pools Raises Asthma Risk
9. Tight necktie may raise glaucoma risk
10. Painkillers may raise miscarriage risk
11. New Treatment To Raise Good Cholesterol
Post Your Comments:
(Date:10/10/2015)... ... October 10, 2015 , ... ... is pleased to be recognized by The National Law Journal for inclusion in ... 50 law firms across the United States who obtained the largest awards for ...
(Date:10/9/2015)... Los Angeles, CA (PRWEB) , ... October 09, 2015 , ... ... awareness for breast cancer victims, survivors, and the ongoing effort to find a cure. ... patients another outlet for helping women in need. With their Bra Collection Campaign, Beverly ...
(Date:10/9/2015)... ... October 09, 2015 , ... Advanced Hearing ... Tennessean's eighth annual Toast of Music City, a reader’s choice awards featuring favorite ... and cast votes for their favorite businesses in over 200 categories, including best ...
(Date:10/9/2015)... ... October 09, 2015 , ... The Asthma and Allergy Foundation of America ... Control and Prevention (CDC) to improve the knowledge and skills of underserved adults with ... a project by the CDC and allows AAFA to continue vital efforts to educate ...
(Date:10/9/2015)... ... 09, 2015 , ... MMJ PhytoTech Limited announced that they ... airing 1st QT 2016 via the Discovery Channel. Dates and show times TBA. ... – a global leader in the field of commercializing medicinal grade cannabis. As ...
Breaking Medicine News(10 mins):
... Newsletter for Healthcare ProfessionalsVOORHEES, N.J., March 30 ... urticaria (hives) and angioedema can be challenging, ... a number of immunologic and nonimmunologic mechanisms. ... seemingly identical presentation of angioedema subtypes. It ...
... March 30 One of the longest-term survivors of ... honored today by the Mesothelioma Applied Research Foundation with ... July of 1998, in St. Charles, Missouri, then-42 year-old ... over a few digestive symptoms. Nine days later, he ...
... Indigestion, constipation can be relieved with ancient remedies, ... -- Japanese herbal medicines may help people with ... -- that don,t respond to conventional treatments, a ... these gastrointestinal "motility disorders" don,t work or cause ...
... Headline All-Day FestivalWASHINGTON, March 30 Celebrating its 30th ... National Kidney Foundation is DC,s biggest one-day rock festival ... chili cooks competing for top honors. The event is ... 9:00 p.m. at RFK Stadium Festival Grounds.For the past ...
... and Complex-Event Processing (CEP) Technologies Unified in Rx ... First Choice Professionals, LLC., today announced a partnership ... ), to provide healthcare organizations with advanced technology ... renowned healthcare integration group will combine talents with ...
... Medical Innovations, Inc. (NYSE: IMA ), a global ... at home through the merger of rapid diagnostics and health ... the new C. DIFF QUIK CHEK COMPLETE (TM) rapid ... Clostridium difficile associated disease (CDAD). This follows TECHLAB(R), ...
Cached Medicine News:
(Date:10/8/2015)... Oct. 8, 2015  Allergan plc (NYSE: AGN ... it will hold its R&D Day on November 4, ... – to 1:00 p.m. PT). The company will also ... at 9:00 a.m. ET (6:00 a.m. PT). ... --> Logo - ...
(Date:10/8/2015)... CAMBRIDGE, Mass. , Oct. 8, 2015 /PRNewswire/ ... has awarded approximately $40 million to the Broad ... whole genome sequencing of 20,000 individuals, as well ... sequencing and metabolite profiling. Trans-Omics for ... an initial step toward a larger initiative, which ...
(Date:10/8/2015)... FRANCISCO , Oct. 8, 2015  Nektar Therapeutics ... the Company,s pain and oncology portfolio during an Investor ... - 3:30 p.m. Eastern Time in New ... carcinoma.  Details of the NKTR-214 Phase 1/2 clinical program ... CD122-biased immune-stimulatory cytokine designed to preferentially stimulate the production ...
Breaking Medicine Technology:
... (SIX: RO, ROG; OTCQX: RHHBY) announced today that the David ... be using the Roche LightCycler ® 480 System, a ... gene expression and genetic variation, in advanced cancer research. ... 480 System to support several key areas of research it ...
... 2011 /PRNewswire/ -- Royal Philips Electronics ... States availability of the Ingenia MRI system, the ... Previously available in Europe, Canada and Japan, the ... Food and Drug Administration. Driven by Philips commitment ...
Cached Medicine Technology:
CDIs new improved Implant Stabilizer has super-soft elastic bands with lace trim....
Bras and Breast Support...
Post-Surgical compression garments...
... The Albumin Cobalt Binding (ACB®) Test is ... Modified Albumin (IMA®) by measuring the cobalt ... serum sample. First identified in the early ... comes in contact with ischemic tissue in ...
Medicine Products: