Navigation Links
Acrylamide Raises Kidney Cancer Risk
Date:5/9/2008

Study found high intake of compound in fried foods, snacks, coffee upped chances of disease

FRIDAY, May 9 (HealthDay News) -- Consuming large amounts of acrylamide, a chemical commonly found in French fries, cakes, snacks and even coffee, appears to raise the risk of kidney cancer, especially in smokers, Dutch researchers report.

"Ours is the first report of a positive association between dietary acrylamide intake and renal cell [kidney] cancer," said study author Janneke Hogervorst, a researcher at Maastricht University in the Netherlands.

The report is published in the May issue of the American Journal of Clinical Nutrition.

Studies of the chemical have been ongoing since 1994, when the International Agency for Research on Cancer classified the chemical as a probable human carcinogen. Experts thought the main exposure was environmental, through cigarette smoke and, to a lesser extent, cosmetics.

But in 2002, Swedish scientists reported the presence of the chemical in carbohydrate-rich foods produced at high temperatures, including French fries and potato chips.

Studies of the chemical's link to various cancers have yielded mixed results.

The Dutch research team took data from the Netherlands Cohort Study on diet and cancer, which includes more than 120,000 men and women, aged 55 to 69. They followed them for more than 13 years, looking at all the cases of kidney, bladder and prostate cancers. They took a random sample of 5,000 people to look at their dietary habits.

The average intake of acrylamide from the diet was 21.8 micrograms -- a little less than what is included in a 2.5-ounce serving of French fries. Those who took in the most -- averaging 40.8 micrograms a day -- had a 59 percent higher risk of kidney cancer (but not the other cancers) than those consuming the least.

For most people, coffee was the major source of the chemical. However, a popular snack, Dutch spiced cake, was the main source of the chemical for those consuming the most. The relationship was found to be stronger for smokers.

For each additional 10 micrograms ingested of the chemical, kidney cancer risk increased by 10 percent, the researchers found.

In another study published in the same issue of the journal, researchers found no association between dietary fat intake and prostate cancer risk.

One expert praised the acrylamide study but added that more research is needed. It is also difficult to know how much impact smoking has on the cancer risk, said Marji McCullough, a nutritional epidemiologist for the American Cancer Society.

"Smoking is a [known] risk factor for this [kidney] cancer," she said.

Exactly how the acrylamide boosts cancer risk isn't known, she added, "but the hypothesis is that metabolites [breakdown products] of the acrylamide cause DNA damage."

Limiting the consumption of foods containing the chemical is wise, Hogervorst said. "Also, in preparing food at home, fry potatoes at temperatures below 175 degrees Celsius and fry them to gold-yellow, not dark brown [the more brown, the more acrylamide]. The same goes for making toast and cookies."

McCullough added: "It's best not to smoke and to maintain an ideal body weight. One way to maintain a healthy body weight is a healthy diet."

And that, of course, means limiting the French fries and other snacks.

More information

To learn more about kidney cancer, visit the American Cancer Society.



SOURCES: Marji McCullough, Sc.D., R.D., nutritional epidemiologist, American Cancer Society, Atlanta; Janneke Hogervorst, M.Sc., Maastricht University, Maastricht, the Netherlands; May 2008, American Journal of Clinical Nutrition


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Acrylamide Wont Raise Breast Cancer Risk
2. Reese Witherspoon Helps Celebrate Avon Walk for Breast Cancer Washington, D.C. - Weekend-Long Event Raises $8.1 Million
3. Astute Medical Raises $6.2 Million in Series A Financing Round Led by De Novo Ventures
4. Study raises questions about prostate cancer therapies targeting IGF-1
5. Report raises C. diff concerns; yeast-based probiotic shown to help significantly reduce recurrence
6. USCCB Official Praises Senate Passage of Genetic Information Nondiscrimination Act
7. The Womens Health II Medical Education Network Raises Awareness About the Diagnosis and Management of Womens Health Issues
8. VisEn Medical Raises $5.0 Million in Expanded Series B Financing
9. Consumer Watchdog Praises CA HMO Regulators Promise to Reinstate Health Coverage for Wrongfully Cancelled Patients; Cautions That All Health Costs During Gap Must be Covered
10. FRC Action Praises John McCains Pro-Life Comments
11. Standard & Poors Raises Gerresheimer Rating to BB+
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Acrylamide Raises Kidney Cancer Risk
(Date:5/27/2016)... ... May 27, 2016 , ... This campaign aims to provide a path ... a society can control and change. , As nearly 795,000 Americans suffering from a ... the United States. Plus, with an estimated 129,000 of these people dying from stroke, ...
(Date:5/27/2016)... Texas (PRWEB) , ... May 27, 2016 , ... ... satisfying Army body fat composition regulations. This is the first time that Coolsculpting ... normally screened at least every six months to ensure they meet the prescribed body-fat ...
(Date:5/27/2016)... (PRWEB) , ... May 27, 2016 , ... ... in scholarships to students studying complementary medicine. Allison Outerbridge is this year’s ... her award on May 18 at the university’s Student Leadership Awards ceremony. , ...
(Date:5/26/2016)... , ... May 26, 2016 , ... There are many ... Dog and Sausage Council (NHDSC) suggests that Americans prefer their dogs straight off the ... percent say grilling is their favorite way to cook a hot dog, far outpacing ...
(Date:5/26/2016)... , ... May 26, 2016 , ... ... clinical outcomes, hosted members and suppliers for its inaugural Member Conference at the ... their mission of elevating the operational health of America’s healthcare providers. , The ...
Breaking Medicine News(10 mins):
(Date:5/25/2016)... GERMANTOWN, Maryland , May 25, 2016 ... bedient dringenden Bedarf zur ... QIAGEN N.V. (NASDAQ: QGEN ; Frankfurt ... und Entwicklungsvereinbarung mit Therawis Diagnostics GmbH zur Entwicklung ... zu sein. Ein erstes Projekt wird die Entwicklung ...
(Date:5/25/2016)... May 25, 2016  According to Kalorama Information, the ... in 2015.  Though these are challenging times in ... for success for companies that remain optimistic and ... new growth prospects medical device companies spend a ... development (R&D) than do companies in other industries.  ...
(Date:5/25/2016)... NORTH CHESTERFIELD, Va. , May 25, 2016 ... commercially-available next-generation sequencing test for wounds and infections. ... fungi, ALL parasites, and select viruses. The test ... infected area. David G. ... advanced molecular testing to facilitate wound healing: "We ...
Breaking Medicine Technology: