Navigation Links
Acrylamide Raises Kidney Cancer Risk
Date:5/9/2008

Study found high intake of compound in fried foods, snacks, coffee upped chances of disease

FRIDAY, May 9 (HealthDay News) -- Consuming large amounts of acrylamide, a chemical commonly found in French fries, cakes, snacks and even coffee, appears to raise the risk of kidney cancer, especially in smokers, Dutch researchers report.

"Ours is the first report of a positive association between dietary acrylamide intake and renal cell [kidney] cancer," said study author Janneke Hogervorst, a researcher at Maastricht University in the Netherlands.

The report is published in the May issue of the American Journal of Clinical Nutrition.

Studies of the chemical have been ongoing since 1994, when the International Agency for Research on Cancer classified the chemical as a probable human carcinogen. Experts thought the main exposure was environmental, through cigarette smoke and, to a lesser extent, cosmetics.

But in 2002, Swedish scientists reported the presence of the chemical in carbohydrate-rich foods produced at high temperatures, including French fries and potato chips.

Studies of the chemical's link to various cancers have yielded mixed results.

The Dutch research team took data from the Netherlands Cohort Study on diet and cancer, which includes more than 120,000 men and women, aged 55 to 69. They followed them for more than 13 years, looking at all the cases of kidney, bladder and prostate cancers. They took a random sample of 5,000 people to look at their dietary habits.

The average intake of acrylamide from the diet was 21.8 micrograms -- a little less than what is included in a 2.5-ounce serving of French fries. Those who took in the most -- averaging 40.8 micrograms a day -- had a 59 percent higher risk of kidney cancer (but not the other cancers) than those consuming the least.

For most people, coffee was the major source of the chemical. However, a popular snack, Dutch spiced cake, was the main source of the chemical for those consuming the most. The relationship was found to be stronger for smokers.

For each additional 10 micrograms ingested of the chemical, kidney cancer risk increased by 10 percent, the researchers found.

In another study published in the same issue of the journal, researchers found no association between dietary fat intake and prostate cancer risk.

One expert praised the acrylamide study but added that more research is needed. It is also difficult to know how much impact smoking has on the cancer risk, said Marji McCullough, a nutritional epidemiologist for the American Cancer Society.

"Smoking is a [known] risk factor for this [kidney] cancer," she said.

Exactly how the acrylamide boosts cancer risk isn't known, she added, "but the hypothesis is that metabolites [breakdown products] of the acrylamide cause DNA damage."

Limiting the consumption of foods containing the chemical is wise, Hogervorst said. "Also, in preparing food at home, fry potatoes at temperatures below 175 degrees Celsius and fry them to gold-yellow, not dark brown [the more brown, the more acrylamide]. The same goes for making toast and cookies."

McCullough added: "It's best not to smoke and to maintain an ideal body weight. One way to maintain a healthy body weight is a healthy diet."

And that, of course, means limiting the French fries and other snacks.

More information

To learn more about kidney cancer, visit the American Cancer Society.



SOURCES: Marji McCullough, Sc.D., R.D., nutritional epidemiologist, American Cancer Society, Atlanta; Janneke Hogervorst, M.Sc., Maastricht University, Maastricht, the Netherlands; May 2008, American Journal of Clinical Nutrition


'/>"/>
Copyright©2008 ScoutNews,LLC.
All rights reserved  

Related medicine news :

1. Acrylamide Wont Raise Breast Cancer Risk
2. Reese Witherspoon Helps Celebrate Avon Walk for Breast Cancer Washington, D.C. - Weekend-Long Event Raises $8.1 Million
3. Astute Medical Raises $6.2 Million in Series A Financing Round Led by De Novo Ventures
4. Study raises questions about prostate cancer therapies targeting IGF-1
5. Report raises C. diff concerns; yeast-based probiotic shown to help significantly reduce recurrence
6. USCCB Official Praises Senate Passage of Genetic Information Nondiscrimination Act
7. The Womens Health II Medical Education Network Raises Awareness About the Diagnosis and Management of Womens Health Issues
8. VisEn Medical Raises $5.0 Million in Expanded Series B Financing
9. Consumer Watchdog Praises CA HMO Regulators Promise to Reinstate Health Coverage for Wrongfully Cancelled Patients; Cautions That All Health Costs During Gap Must be Covered
10. FRC Action Praises John McCains Pro-Life Comments
11. Standard & Poors Raises Gerresheimer Rating to BB+
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
Acrylamide Raises Kidney Cancer Risk
(Date:5/27/2017)... ... May 27, 2017 , ... Most us are familiar with ... new study from the Osteoarthritis Initiative shows that certain people who experience ... this in advance may give doctors the opportunity to treat patients before the problem ...
(Date:5/26/2017)... ... May 26, 2017 , ... Leading CEOs from ... May 30th and 31st at The Four Seasons Hotel Boston. , The ... life sciences, offering exclusive access to key decision makers who influence deal making ...
(Date:5/26/2017)... Clara, Calif. (PRWEB) , ... May 26, 2017 ... ... announces the integration of the CareFusion NOX-T3 portable sleep monitor with its Somnoware ... provides a consistent, browser-based interface for diagnostic device operations. With this platform, initializing ...
(Date:5/26/2017)... ... May 26, 2017 , ... via ... antimicrobial, mesh back 24/7 task chair specifically designed for clinical areas. Genie Copper ... thrilled to partner with Cupron® to provide customers with a game changing chair ...
(Date:5/26/2017)... ... May 26, 2017 , ... Yisrayl Hawkins, Pastor and Overseer at The House ... focusing on the Peace Agreements being discussed by President Donald Trump and the rest ... to try to speed up peace talks in the continuous battle between Israel and ...
Breaking Medicine News(10 mins):
(Date:5/4/2017)... 2017  A new tight-tolerance microextrusion medical tubing ... materials, is being launched by Natvar, a Tekni-Plex ... in recent years to service a wide variety ... More expensive materials such as glass and fluoropolymers ... to their ability to consistently hold tolerances. This ...
(Date:5/3/2017)... 2017  Kalorama Information notes that transplant diagnostics ... year and this is projected to continue to ... (HSCT) or bone marrow transplants require histocompatibility between ... for this task. This according to a new ... The various PCR-based methodologies, Sanger sequencing and NGS ...
(Date:5/2/2017)... NEW YORK and LONDON ... distributor of market intelligence, MarketResearch.com is pleased to announce ... Consulting AB that allows for the marketing and ... market analyses through the MarketResearch.com website. The ... access to complete product descriptions and tables of contents ...
Breaking Medicine Technology: