Navigation Links
Acetaldehyde in alcohol -- no longer just the chemical that causes a hangover
Date:3/19/2009

New evidence by researchers at the Centre for Addiction and Mental Health (CAMH) and researchers in Germany shows that drinking alcohol is the greatest risk factor for acetaldehyde-related cancer. Heavy drinkers may be at increased risk due to exposure from multiple sources.

Acetaldehyde is ubiquitous in daily life in Ontario. Widely present in the environment, it is inhaled from the air and tobacco smoke, ingested from alcohol and foods, and produced in the human body during the metabolism of alcoholic beverages. Research indicates that this organic chemical plays a significant role in the development of certain types of cancers (especially of the upper digestive tract), and it is currently classified as possibly carcinogenic by the International Agency for Research on Cancer of the World Health Organization. New research from CAMH in Toronto and the Chemical and Veterinary Investigation Laboratory Karlsruhe (CVUA) in Germany recently provided the necessary methodology for calculating the risk for the ingestion of alcoholic beverages.

The team found that risk from ingesting acetaldehyde via alcoholic beverages alone may exceed usual safety limits for heavy drinkers. Their risk assessment study found that the average exposure to acetaldehyde from alcoholic beverages resulted in a life-time cancer risk of 7.6/10,000, with higher risk scenarios (e.g. contaminations in unrecorded alcohol) in the range of 1 in 1,000. As such, the life-time cancer risks for acetaldehyde from ingestion of alcoholic beverages greatly exceed the usual limits for cancer risks from the environment.

The research team noted, however, that this risk is compounded by the addition of acetaldehyde exposure from different sources. "The problem with acetaldehyde has been that although it has been recognized as toxic by Health Canada some years ago, most risk assessments to date were based on one source of exposure only" explained Dr. Jrgen Rehm, the lead scientist of the Toronto group and head of the Public Health and Regulatory Policies section at CAMH. "This has led to a negligence of the overall risk."

For example, in Toronto, even though there are limits for air exposure of acetaldehyde set by the responsible Public Health agency, these limits have been surpassed in the past. Alone, the risks associated with surpassing limits of acetaldehyde from the air may not yet be alarming, but for heavy drinkers and smokers, it adds to the acetaldehyde levels already received from these sources. This overall risk then surpasses established safety limits.

"Their risk assessment of acetaldehyde present as a congener in alcoholic beverages touches the tip of the iceberg," according to a Commentary on the CAMH/CVUA study in the journal Addiction.

Based on their study the scientists of CAMH recommend:

  • That the classification of acetaldehyde with respect to cancer be re-examined, incorporating new evidence which points to an additional cancer risk to humans.
  • That a further risk assessment should take into consideration all sources of exposure from this substance.
  • That the risk for cancer stemming from acetaldehyde from alcoholic beverages is recognized, and necessary preventive steps are taken to reduce the acetaldehyde content in alcoholic beverages.
  • That the overall level of acetaldehyde exposure be minimized to the lowest level technically possible.


'/>"/>

Contact: Michael Torres
michael_torres@camh.net
416-595-6015
Centre for Addiction and Mental Health
Source:Eurekalert

Related medicine news :

1. The Recovery Place Helps Hundreds of Patients Through Drug and Alcohol Rehabilitation
2. Affordable Drug and Alcohol Rehab Ranch Residence is Saving Lives in Washington
3. Shootings Linked to Alcohol-to-Go Outlets, Study Finds
4. The Rev. Joseph C. Martin, Leading Authority on Alcoholism and Addiction Treatment, Dies at 84
5. Media Images of Alcohol Can Drive You to Drink
6. Alcohol consumption may increase pancreatic cancer risk
7. Owning alcohol-branded merchandise associated with teen drinking behaviors
8. Is telmisartan effective in treating non-alcoholic steatohepatitis?
9. Alcohol-Branded Apparel Linked to Adolescent Drinking
10. Alcohol types and socioeconomic status are associated with Barretts esophagus risk
11. Million women study shows even moderate alcohol consumption associated with increased cancer risk
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/23/2017)... , ... January 23, 2017 , ... ... educational institution’s inaugural K-20 Education Summit to be held March 23-25, 2017 in ... by Jan. 25, 2017. , The keynote speakers include Dr. Michelle R. Weise, ...
(Date:1/23/2017)... Dc (PRWEB) , ... January 23, 2017 , ... ... American University is taught by healthcare management and evaluation leaders with decades of ... fee-for-service to pay-for-value in the United States healthcare system, there is a renewed ...
(Date:1/23/2017)... ... January 23, 2017 , ... METTLER TOLEDO has ... Chemistry by Applying Simple PAT Tools . , Crystallization is a ... the desired product. Chemists now spend more time developing better intermediate and ...
(Date:1/23/2017)... ... ... Old School Labs™, makers of the wildly popular all-natural sports supplements based ... its growing team of brand ambassadors. The Olympia top finisher and former Big 12 ... year was able to turn professional, participating in the 2013 NPC USA Championships in ...
(Date:1/23/2017)... ... 2017 , ... “Crossing the Bar”: a moving and eloquent drama depicting ... the Bar” is the creation of published author, Charlotte Hotte, a North Carolina native, ... the inspiration of the book to her sister, Denise, wishes to acknowledge her savior, ...
Breaking Medicine News(10 mins):
(Date:1/23/2017)... The American Pharmacists Association (APhA) is excited ... Medically Underserved Areas Enhancement Act (H.R. 592) ... was previously introduced in the 114 th session ... through pharmacists and their patient care services. ... (R-KY), G.K. Butterfield (D-NC), Tom ...
(Date:1/23/2017)... , January 23, 2017 Ahead of ... to see how they have fared at the close: Kite Pharma ... Inc. (NASDAQ: OVAS ), and Regeneron Pharmaceuticals Inc. (NASDAQ: ... Biotechnology shares were relative laggards on Friday, January 20 th , ... our complimentary research reports on these stocks now at: ...
(Date:1/23/2017)... Longer life expectancy and rising healthcare expenditure in developing countries are factors ... BCC Research reveals in its new report that markets in developing ... strong growth due to rising government healthcare spending, increased levels of healthcare ... Reading ... BCC ...
Breaking Medicine Technology: