Navigation Links
Accurate interpretation of antinuclear antibodies test key to confirming autoimmune disease
Date:1/4/2011

between healthy individuals and patients with autoimmune disease which is essential to accurately interpret the test results," explained Dr. Andrade. Researchers determined that positive ANA-HEp-2 tests in healthy participants occurred predominantly as a nuclear fine speckled (NFS) pattern (at low to moderate titer) or as a nuclear dense fine speckled (NDFS) pattern (frequently at high titer) in 46% and 33% of ANA-positive healthy individuals, respectively. Healthy participants did not present a nuclear coarse speckled (NCS) or a nuclear homogeneous (Ho) pattern.

In those with autoimmune disease the ANA-HEp-2 showed positive results at a predominantly moderate to high titer. A distinct ANA-HEp-2 pattern profile was observed, characterized by the absence of the NDFS pattern and the exclusive occurrence of the NCS (26%), centromeric (8%), nuclear homogeneous (7%), and cytoplasmic dense fine speckled (3%) patterns. ANA-positive patients with confirmed autoimmune diseases also showed the presence of the NFS (42%), but at a higher titer than in healthy individuals.

At the end of a 4-year follow-up period 73% of the ANA-positive healthy individuals retained a positive test result, but did not develop any symptoms of autoimmune rheumatic disease. "Our study confirms that the ANA-HEp-2 pattern is critical in properly diagnosing autoimmune disorders and future research should attempt to reproduce the interpretation of test results among different ANA experts and ANA-HEp-2 slides brands," Dr. Andrade concluded.


'/>"/>

Contact: Dawn Peters
healthnews@wiley.com
781-388-8408
Wiley-Blackwell
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Rapid Flu Test Most Accurate for Young Kids
2. LifeScan Recalls Specific Lots of Consumer and Professional OneTouch(R) SureStep(R) Test Strips Due To Inaccurate Readings at High Levels
3. Study: Mechanomyography to be accurate in detecting nerves during minimally invasive spine surgery
4. Whole body MRI is highly accurate in the early detection of breast cancer metastases
5. Innovative Technology Developed at AGH Accurately Monitors Healthcare Professionals' Handwashing Practices, Study Shows
6. Survey: Many Young Women Lack Accurate Information about STDs
7. Study finds cancer information on Wikipedia is accurate, but not very readable
8. New formula gives first accurate peak heart rate for women
9. Latino children with asthma less accurate in determining their lung function
10. Experimental TB Test Called Fast and Accurate
11. Blood test accurately predicts death from prostate cancer up to 25 years in advance
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/21/2015)... Displays & Exhibits, Inc. a division ... show exhibit building industry, announced a management change of ... Absolute Exhibits in Tustin, California.“It is very important to ... the variation in quality as offered by overseas trade ... Adduru. Mr. Adduru is the new manager of Displays ...
(Date:4/21/2015)... 2015 On April 2, 2015, Elle ... Achieve Kylie Jenner Lips With Disastrous Results,” ... themselves while attempting an at-home lip augmentation ... that creating an airlock around one’s mouth for several ... and achieve Kylie Jenner’s now famous pout. (see: goo.gl/dFQW2L) ...
(Date:4/21/2015)... 21, 2015 Top medical tourism firm, ... for their ongoing commitment to providing superior patient experiences. ... provide patients with the best possible experience for a ... and body. , Executives at Ojas Aesthetic Clinic persistently ... of — nothing about you, without you — through ...
(Date:4/21/2015)... 2015 AvePoint, the established ... today announced a new enhancement to DocAve Policy ... Office 365 Management Activity API. This integration creates a ... and take action on all events that take place ... 365 Management Activity API provides customers with greater transparency ...
(Date:4/21/2015)... 2015 Lyft has announced the ... otolaryngologists, bringing the most advanced speech-recognition technology to ... Otolaryngologists can now experience the full benefits of ... in the industry, Lyft, which offers value-added support ... , “Lyft is very excited to be able ...
Breaking Medicine News(10 mins):Health News:Displays & Exhibits Reveals Tustin, California Showroom Under New Management 2Health News:Celebrity Cosmetic Surgeon Comments on Report of Teen Girls Injuring Themselves Attempting Kylie Jenner-Inspired Twitter Challenge 2Health News:VisitandCare.com Cosmetic Surgery Provider in India Earns Recognition for Patient Satisfaction 2Health News:VisitandCare.com Cosmetic Surgery Provider in India Earns Recognition for Patient Satisfaction 3Health News:AvePoint Integrates Microsoft Office 365 Management Activity API into DocAve Policy Enforcer for Proactive SharePoint Monitoring 2Health News:AvePoint Integrates Microsoft Office 365 Management Activity API into DocAve Policy Enforcer for Proactive SharePoint Monitoring 3Health News:Lyft Expands Its Offerings to Include Dragon® Medical Practice Edition 2 for Otolaryngologists. 2
... of two proteins in mammalian embryos prevents the development ... at the Medical College of Wisconsin, Milwaukee, has found. ... issue of Developmental Biology, was led by Stephen Duncan, ... the Medical College. , This is the first study ...
... second monoclonal antibody drug to chemotherapy looks promising for ... Clinic researchers working with the North Central Cancer Treatment ... analysis were released May 15 as part of the ... Oncology. , Researchers found that 95 percent of ...
... Shandong, China, May 16 /Xinhua-PRNewswire-FirstCall/ --,Shengtai Pharmaceutical, Inc. ... a leading manufacturer and distributor,of high-quality, pharmaceutical grade ... the three months ended March 31, 2008., ... -- Sales increased 64.8% to $20.7 million ...
... Jazz,Pharmaceuticals, Inc. (Nasdaq: JAZZ ) announced today that ... presentation at two,upcoming investor conferences., Mr. Myers will ... in London at 9:30 a.m. BST (4:30 a.m. EDT) ... 2008 Mr. Myers will present at the FBR Capital,Markets ...
... China Yingxia,International, Inc. (OTC Bulletin Board: CYXI) ("China ... nutraceutical industry engaged in the,development, manufacture and distribution ... products in the People,s Republic,of China ("PRC"), today ... March 31, 2008., First Quarter 2008 ...
... anti-inflammatory medication also known by the trade name Celebrex, ... proliferation measurement of precancerous lesions in the lung, according ... D. Anderson Cancer Center. This finding demonstrates the significance ... at higher risk of developing the disease. , The ...
Cached Medicine News:Health News:Medical College of Wisconsin researchers identify proteins that help develop mammalian hearts 2Health News:Adding epratuzumab to standard therapy 2Health News:Shengtai Pharmaceutical, Inc. Reports Third Quarter Results of Fiscal Year 2008 2Health News:Shengtai Pharmaceutical, Inc. Reports Third Quarter Results of Fiscal Year 2008 3Health News:Shengtai Pharmaceutical, Inc. Reports Third Quarter Results of Fiscal Year 2008 4Health News:Shengtai Pharmaceutical, Inc. Reports Third Quarter Results of Fiscal Year 2008 5Health News:Shengtai Pharmaceutical, Inc. Reports Third Quarter Results of Fiscal Year 2008 6Health News:Shengtai Pharmaceutical, Inc. Reports Third Quarter Results of Fiscal Year 2008 7Health News:Shengtai Pharmaceutical, Inc. Reports Third Quarter Results of Fiscal Year 2008 8Health News:Shengtai Pharmaceutical, Inc. Reports Third Quarter Results of Fiscal Year 2008 9Health News:Shengtai Pharmaceutical, Inc. Reports Third Quarter Results of Fiscal Year 2008 10Health News:Shengtai Pharmaceutical, Inc. Reports Third Quarter Results of Fiscal Year 2008 11Health News:Shengtai Pharmaceutical, Inc. Reports Third Quarter Results of Fiscal Year 2008 12Health News:China Yingxia International, Inc. Reports First Quarter 2008 Results 2Health News:China Yingxia International, Inc. Reports First Quarter 2008 Results 3Health News:China Yingxia International, Inc. Reports First Quarter 2008 Results 4Health News:China Yingxia International, Inc. Reports First Quarter 2008 Results 5Health News:China Yingxia International, Inc. Reports First Quarter 2008 Results 6Health News:China Yingxia International, Inc. Reports First Quarter 2008 Results 7Health News:China Yingxia International, Inc. Reports First Quarter 2008 Results 8Health News:China Yingxia International, Inc. Reports First Quarter 2008 Results 9Health News:Celebrex shows benefit in first-of-its-kind lung cancer chemoprevention trial 2Health News:Celebrex shows benefit in first-of-its-kind lung cancer chemoprevention trial 3
(Date:4/21/2015)... MONROVIA, Calif. , April 21, 2015 ... developer, manufacturer and marketer of implantable lenses and delivery ... of Directors has appointed J. Steven Roush , ... total number of members on STAAR,s Board to seven.Mr. ... reporting agencies expertise, largely gained over a 39 year ...
(Date:4/21/2015)... and CAMBRIDGE, Mass. ... ( Tokyo : 4503) and Potenza ... of immuno-oncology programs, today announced an exclusive research ... is to advance a portfolio consisting of programs ... pathways, co-stimulatory signals and regulatory T cells. The ...
(Date:4/21/2015)... TOKYO , April 21, 2015 /PRNewswire/ ... conferences, has just announced Medtech Partnering Forum 2015 ... technology industry. The event, held May 28–29 in ... international medtech partnering conference in Japan ... new developments in the rapidly changing medical technology industry ...
Breaking Medicine Technology:J. Steven Roush, CPA Appointed to STAAR Surgical Board of Directors 2J. Steven Roush, CPA Appointed to STAAR Surgical Board of Directors 3Astellas Pharma And Potenza Therapeutics Partner To Build A Portfolio Of Immuno-Oncology Therapeutics 2Astellas Pharma And Potenza Therapeutics Partner To Build A Portfolio Of Immuno-Oncology Therapeutics 3Inaugural Medtech Partnering Forum to feature leading global medtech decision makers this May 28-29, 2015 in Tokyo, Japan 2Inaugural Medtech Partnering Forum to feature leading global medtech decision makers this May 28-29, 2015 in Tokyo, Japan 3Inaugural Medtech Partnering Forum to feature leading global medtech decision makers this May 28-29, 2015 in Tokyo, Japan 4
... Feb. 9, 2011 GeoVax Labs, Inc. (OTC Bulletin ... develops and tests innovative HIV/AIDS vaccines, announced today the ... Alabama Vaccine Research Clinic (AVRC) of the University of ... therapeutic vaccine trial. Although the GeoVax vaccines are currently ...
... The Covaris® LE220™ high performance ultra-sonicator has received ... at the LabAutomation 2011 conference in Palm Springs ... laboratory automation conference and exhibition, bringing science, technology, and ... LabAutomation are evaluated by a team of industry experts. ...
Cached Medicine Technology:GeoVax Launches a Second Clinical Site to Test the Therapeutic Benefit of its HIV Vaccine 2GeoVax Launches a Second Clinical Site to Test the Therapeutic Benefit of its HIV Vaccine 3Covaris Receives the Society for Laboratory Automation and Screening (SLAS) New Product Award at LabAutomation 2011 2
Used to introduce large devices for vascular intervention....
Used to introduce large devices for vascular intervention....
Used to introduce balloon, closed and non-tapered end catheters or other devices for intervention....
Used to introduce balloon, closed and non-tapered end catheters and other devices for intervention....
Medicine Products: