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Access Pharmaceuticals Presents ProLindac(TM) Data at the AACR-NCI-EORTC Symposium 2008
Date:10/21/2008

els of DACH platinum with an improved side effect profile."

The "Molecular Targets and Cancer Therapeutics" symposium is organized jointly by three leading oncology societies; the American Association for Cancer Research (AACR), National Cancer Institute (NCI) and the European Organization for Research and Treatment of Cancer (EORTC), and attracts researchers and pharmaceuticals companies from all major territories. The poster titles are as follows:

Poster #104: Role of p21 in sensitivity to DACH-platinum compounds, oxaliplatin and ProLindacTM, in human cancer cells.

Poster #143: Ex vivo plasma protein binding and in vitro evaluations of AP5346, a novel platinum-bound biopolymer: Evidence showing that >72hr DACH-platinum release may play a major role in cytotoxicity.

Poster #214: AP5346 (ProLindacTM), a pH-dependent polymer-vectorized DACH platinum, is active in borderline potentially platinum-sensitive ovarian cancer (OC) patients: results from an ongoing Phase I/II trial.

About ProLindac(TM):

ProLindac is a novel DACH platinum prodrug which has been shown to be active in a wide variety of solid tumors in both preclinical models and in human trials. Access believes that ProLindac's unique molecular design potentially could eliminate some of the toxic side effects seen in the currently marketed DACH platinum, Eloxatin, which has sales in excess of $2 billion.

About Access:

Access Pharmaceuticals, Inc. is an emerging biopharmaceutical company that develops and commercializes propriety products for the treatment and supportive care of cancer patients. Access' products include ProLindac(TM), currently in Phase 2 clinical testing of patients with ovarian cancer, and MuGard(TM) for the management of patients with mucositis. The company also has other advanced drug delivery technologies including Cobalamin(TM)-mediated targeted delivery and oral drug delivery, its proprietary nanopolymer delivery technology based on
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SOURCE Access Pharmaceuticals, Inc.
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