Navigation Links
Accelerated Development of New Treatment for Multi Drug-Resistant Tuberculosis: TB Alliance and Tibotec Announce Unique Partnership to Develop TMC207
Date:6/17/2009

SEATTLE, June 17 /PRNewswire/ --

    When:    Wednesday, June 17, 2009, 10:30am Eastern (9:30am Central; 8:30am
             Mountain; 7:30am Pacific)

    Dial-in: 1-877-879-6184 (toll-free)
             1-719-325-4759 (local access)
             Conference Title: TB Alliance/Tibotec Briefing
             Participant passcode: 2895940

    Where:   Pacific Health Summit
             Bell Harbor International Conference Center
             Pacific Board Room
             Seattle, Washington

Today at the Pacific Health Summit, the Global Alliance for TB Drug Development (TB Alliance) and Tibotec announced a unique partnership to accelerate multi drug-resistant tuberculosis (MDR-TB) drug development. The two organizations will work together to develop TMC207, which is currently being studied in Phase II clinical trials in patients with MDR-TB. TMC207 could become the first tuberculosis treatment in 40 years to feature a new mechanism of action against the disease. Novel drugs are urgently needed to fight deadly MDR-TB, which caused an estimated 130,000 deaths worldwide in 2007.

    Speakers:
        Mel Spigelman, M.D., president and CEO, Global Alliance for TB Drug
         Development
        Paul Stoffels, M.D., Global Head Pharmaceutical Research and
         Development, Johnson & Johnson
        Jaime N. Bayona, M.D., M.P.H., director, Socios En Salud (Partners
         In Health) Lima, Peru

Background:

Interim data from an ongoing Phase II study of TMC207 were recently published in the New England Journal of Medicine. In the placebo-controlled study of 47 patients with MDR-TB, it was found that 48 percent of patients receiving TMC207 in combination with standard treatment converted to negative sputum culture after eight weeks compared with 9 percent of those who received placebo and standard treatment. The safety and efficacy of TMC207 will be further evaluated in Phase 3 clinical trials.

Tuberculosis kills one person approximately every twenty seconds. MDR-TB, which is characterized by resistance to at least two of the most powerful medicines in today's standard, four-drug regimen for drug-susceptible TB, is of particular concern given the rapid rise in the number of cases throughout the world and the difficulties in treating it. There were an estimated 510,000 incident cases and 130,000 fatalities due to MDR-TB in 2007. Drug-resistant strains are extremely difficult and expensive to treat and novel drugs are urgently needed to fight these deadly strains.

Dr. Mel Spigelman, the president and CEO of the TB Alliance, and Dr. Paul Stoffels, Global Head Pharmaceutical Research and Development, Johnson & Johnson, will discuss this landmark partnership. Dr. Jaime Bayona, M.D., director and founder of Socios En Salud, Lima, Peru, was integral in helping Paul Famer, M.D., Ph.D., establish a pilot MDR-TB treatment program clinic in Peru. As an authority on approaches to the control of MDR-TB, Dr. Bayona can speak first-hand to the urgent need for novel treatments for MDR-TB.

Contact:

Joanna Breitstein, Global Alliance for TB Drug Development, +1 917-361-0683, joanna.breitstein@tballiance.org

Karen Manson, Tibotec, +32-479-89-47-99, kmanson@its.jnj.com

Sarah Bailey, GCI Health, +1 212-537-8291, sarah.bailey@gcihealth.com


'/>"/>
SOURCE TB Alliance; Tibotec
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Scripps Florida scientists devise accelerated method to determine infectious prion strains
2. Adoption of Consumer-Driven Health Plans Accelerated by Recession
3. Academy of Lymphatic Studies Announces Accelerated Hybrid Online Program
4. Effects of smoking linked to accelerated aging protein
5. UC San Diego engineers develop novel method for accelerated bone growth
6. The Foundation for Accelerated Vascular Research Grants $150,000 Wylie Scholar Award for Blood Vessel Research
7. Accelerated Cure Project for Multiple Sclerosis is One Thousand Steps Closer to a Cure for MS
8. American Stock Exchange Lists Merrill Lynchs Accelerated Return Notes Linked to the Amex Health Care Select Sector Index
9. DuPont Chief Financial Officer Reviews Companys Accelerated Growth Plan
10. Adult stem cell changes underlie rare genetic disease associated with accelerated aging
11. Accelerated head growth can predict autism before behavioral symptoms start
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/25/2016)... ... , ... Austin residents seeking Mohs surgery services, can now turn to Dr. ... Russell Peckham for medical and surgical dermatology. , Dr. Dorsey brings specialization to include ... in Mohs Micrographic Surgery completed by Dr. Dorsey was under the direction of Glenn ...
(Date:6/25/2016)... , ... June 25, 2016 , ... ... and non-athletes recover from injury. Recently, he has implemented orthobiologic procedures as a ... area —Johnson is one of the first doctors to perform the treatment. Orthobiologics ...
(Date:6/24/2016)... ... , ... June 19, 2016 is World Sickle Cell Observance Day. In an ... of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued a ... Cell Disease (SCD) is a disorder of the red blood cells, which can cause ...
(Date:6/24/2016)... ... June 24, 2016 , ... Comfort Keepers® of San Diego, ... and the Road To Recovery® program to drive cancer patients to and from their ... to ensure the highest quality of life and ongoing independence. Getting to and ...
(Date:6/24/2016)... Vegas, Nevada (PRWEB) , ... June 24, 2016 ... ... Las Vegas client, The Grove Investment Group (TGIG), has initiated cultivation and processing ... Grove, in Las Vegas and Pahrump, Nevada. , Puradigm is the manufacturer of ...
Breaking Medicine News(10 mins):
(Date:6/26/2016)... June 27, 2016 Jazz Pharmaceuticals plc (Nasdaq: ... under the Hart-Scott-Rodino Antitrust Improvements Act of 1976, as ... Celator Pharmaceuticals, Inc. ("Celator"; Nasdaq: CPXX ) ... Daylight Time). As previously announced on May ... definitive merger agreement under which Jazz Pharmaceuticals has commenced ...
(Date:6/24/2016)... June 24, 2016  Collagen Matrix, Inc., ("Collagen ... and manufacturing of collagen and mineral based medical ... that Bill Messer has joined the ... further leverage the growing portfolio of oral surgery, ... Bill joins the Collagen Matrix executive team ...
(Date:6/24/2016)... , June 24, 2016 ... the "Structural Electronics 2015-2025: Applications, Technologies, Forecasts" ... In-Mold Electronics, Smart Skin, Structural ... Structural electronics involves electronic and/or ... protective structures, replacing dumb structures such as vehicle ...
Breaking Medicine Technology: