Navigation Links
Accelerated Development of New Treatment for Multi Drug-Resistant Tuberculosis: TB Alliance and Tibotec Announce Unique Partnership to Develop TMC207

SEATTLE, June 17 /PRNewswire/ --

    When:    Wednesday, June 17, 2009, 10:30am Eastern (9:30am Central; 8:30am
             Mountain; 7:30am Pacific)

    Dial-in: 1-877-879-6184 (toll-free)
             1-719-325-4759 (local access)
             Conference Title: TB Alliance/Tibotec Briefing
             Participant passcode: 2895940

    Where:   Pacific Health Summit
             Bell Harbor International Conference Center
             Pacific Board Room
             Seattle, Washington

Today at the Pacific Health Summit, the Global Alliance for TB Drug Development (TB Alliance) and Tibotec announced a unique partnership to accelerate multi drug-resistant tuberculosis (MDR-TB) drug development. The two organizations will work together to develop TMC207, which is currently being studied in Phase II clinical trials in patients with MDR-TB. TMC207 could become the first tuberculosis treatment in 40 years to feature a new mechanism of action against the disease. Novel drugs are urgently needed to fight deadly MDR-TB, which caused an estimated 130,000 deaths worldwide in 2007.

        Mel Spigelman, M.D., president and CEO, Global Alliance for TB Drug
        Paul Stoffels, M.D., Global Head Pharmaceutical Research and
         Development, Johnson & Johnson
        Jaime N. Bayona, M.D., M.P.H., director, Socios En Salud (Partners
         In Health) Lima, Peru


Interim data from an ongoing Phase II study of TMC207 were recently published in the New England Journal of Medicine. In the placebo-controlled study of 47 patients with MDR-TB, it was found that 48 percent of patients receiving TMC207 in combination with standard treatment converted to negative sputum culture after eight weeks compared with 9 percent of those who received placebo and standard treatment. The safety and efficacy of TMC207 will be further evaluated in Phase 3 clinical trials.

Tuberculosis kills one person approximately every twenty seconds. MDR-TB, which is characterized by resistance to at least two of the most powerful medicines in today's standard, four-drug regimen for drug-susceptible TB, is of particular concern given the rapid rise in the number of cases throughout the world and the difficulties in treating it. There were an estimated 510,000 incident cases and 130,000 fatalities due to MDR-TB in 2007. Drug-resistant strains are extremely difficult and expensive to treat and novel drugs are urgently needed to fight these deadly strains.

Dr. Mel Spigelman, the president and CEO of the TB Alliance, and Dr. Paul Stoffels, Global Head Pharmaceutical Research and Development, Johnson & Johnson, will discuss this landmark partnership. Dr. Jaime Bayona, M.D., director and founder of Socios En Salud, Lima, Peru, was integral in helping Paul Famer, M.D., Ph.D., establish a pilot MDR-TB treatment program clinic in Peru. As an authority on approaches to the control of MDR-TB, Dr. Bayona can speak first-hand to the urgent need for novel treatments for MDR-TB.


Joanna Breitstein, Global Alliance for TB Drug Development, +1 917-361-0683,

Karen Manson, Tibotec, +32-479-89-47-99,

Sarah Bailey, GCI Health, +1 212-537-8291,

SOURCE TB Alliance; Tibotec
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Scripps Florida scientists devise accelerated method to determine infectious prion strains
2. Adoption of Consumer-Driven Health Plans Accelerated by Recession
3. Academy of Lymphatic Studies Announces Accelerated Hybrid Online Program
4. Effects of smoking linked to accelerated aging protein
5. UC San Diego engineers develop novel method for accelerated bone growth
6. The Foundation for Accelerated Vascular Research Grants $150,000 Wylie Scholar Award for Blood Vessel Research
7. Accelerated Cure Project for Multiple Sclerosis is One Thousand Steps Closer to a Cure for MS
8. American Stock Exchange Lists Merrill Lynchs Accelerated Return Notes Linked to the Amex Health Care Select Sector Index
9. DuPont Chief Financial Officer Reviews Companys Accelerated Growth Plan
10. Adult stem cell changes underlie rare genetic disease associated with accelerated aging
11. Accelerated head growth can predict autism before behavioral symptoms start
Post Your Comments:
(Date:11/27/2015)... ... , ... A simply groundbreaking television series, "Voices in America", which is hosted ... array of issues that are presently affecting Americans. Dedicated to providing the world with ... changing the subjects consumers focus on, one episode at a time. , In ...
(Date:11/27/2015)... ... November 27, 2015 , ... ... successful and prominent nonprofit healthcare organizations in the country. They have overseen financial ... organizations, and helped advance the healthcare industry as a whole through their advocacy ...
(Date:11/26/2015)... ... November 26, 2015 , ... Patients at Serenity Point ... come together on Thanksgiving Day to share the things that they are most ... Serenity Point YouTube channel, patients displayed what they wrote on index cards, describing ...
(Date:11/26/2015)... ... November 26, 2015 , ... ... to discuss bioavailability and the need to integrate dose form selection in early ... with OBN, the membership organization supporting and bringing together the UK’s emerging life ...
(Date:11/26/2015)... ... November 26, 2015 , ... Pixel ... self-animating trailer titles with ProTrailer: Vintage. This newly styled ProTrailer pack comes with ... work with any font, giving users limitless opportunities to stylize and create designs ...
Breaking Medicine News(10 mins):
(Date:11/26/2015)... 26, 2015 Research and Markets ( ) ... Pacemaker Market Outlook to 2019 - Rise in Cardiac Disorders ... report to their offering. Boston ... Boston scientific and others. --> ... Biotronik, Boston scientific and others. ...
(Date:11/26/2015)... 26, 2015 ... "2016 Future Horizons and Growth Strategies ... Market: Supplier Shares, Country Segment Forecasts, Competitive ... offering. --> ) has ... Future Horizons and Growth Strategies in the ...
(Date:11/26/2015)... 2015 ) has ... of High Viscosity Drugs" report to their ... the addition of the "Self Administration of ... --> Research and Markets ( ... "Self Administration of High Viscosity Drugs" report ...
Breaking Medicine Technology: