Navigation Links
Abnormal stress response seen in toddlers exposed to meth in womb
Date:3/19/2013

PISCATAWAY, NJ Some 2-year-olds whose moms used methamphetamine during pregnancy may have an abnormal response to stressful situations, according to a study in the May issue of the Journal of Studies on Alcohol and Drugs.

Researchers saw the altered response in toddlers who were exposed to meth in the womb and who currently had signs of strife in their livessuch as a mom who drank heavily or had depression or other mental health symptoms. Specifically, the children's levels of the stress hormone cortisol did not rise as they should have during a tense situation (a brief separation from mom).

Other research has linked such "blunted" cortisol responses to higher odds of health and behavioral problems in young peoplefrom substance abuse to delinquency to asthma. That raises concerns about some children exposed to meth in the womb.

"The lack of hormonal stress response that we observed in these children has serious implications, such as a greater risk for depression, anxiety, and attention-deficit/hyperactivity disorder," said lead researcher Namik Kirlic, of the University of Tulsa in Oklahoma.

However, not all of the children in the study showed a blunted stress response. Children with a more stable home environment had a normal hormonal response to stress.

"It's not the meth alone," said senior researcher Barry Lester, Ph.D., director of the Brown Center for Children at Risk at Women & Infants Hospital of Rhode Island and The Warren Alpert Medical School of Brown University. "It's the combination of meth exposure and adversity after birth. We see other things coming into playthe mother's psychological health, alcohol use, exposure to violence at home or in the community. The postnatal environment is hugely important."

The findings are based on 123 2-year-olds whose mothers had used methamphetamine during pregnancy. Lester's team had each child spend time in a room, playing with mom and being observed by a researcher. They then left the child alone for a maximum of two minutesa stressful experience for a 2-year-old. The researchers took saliva samples before and after the stressor to measure each child's cortisol levels.

They found that most of the children (68 percent) showed a blunted cortisol response. And that dampened response was related not only to higher meth exposure in the womb but also to the child's current environmentincluding whether the mother abused alcohol or had depression, anxiety or other mental health issues.

Until now, Lester said, such blunted cortisol reactions had only been seen in older kids. These findings suggest the effects of prenatal drug exposure and stress after birth take shape early: Methamphetamine stimulates the nervous system, so it may affect the developing stress-response system in the fetus. If a young child is then repeatedly exposed to serious stress, Lester explained, "the system wears down."

But the good news, he said, is that kids are "not doomed" by prenatal meth exposure. "If you put that child in a good environment, he or she has every chance of developing normally," Lester said. "I think it's important that these children not get labeled."

On the other hand, because many young kids exposed to meth in the womb may live in stressful environments, it is important to help families early, according to Lester. "Unfortunately," he said, "we are not doing a good job of getting to these children during early infancy."


'/>"/>

Contact: Amy Blustein
ABlustein@wihri.org
401-681-2822
Journal of Studies on Alcohol and Drugs
Source:Eurekalert

Related medicine news :

1. Abnormal growth regulation may occur in children with heart defects
2. Veterans with mild traumatic brain injury have brain abnormalities
3. Epigenomic abnormalities predict patient survival in non-Hodgkins lymphoma
4. Abnormal DNA maintenance related to cancer
5. Documenting womens experiences with chromosome abnormalities found in new prenatal test
6. Abnormal carotid arteries found in children with kidney disease
7. Double drug combo could shut down abnormal blood vessel growth that feeds disease
8. Brain Scans of Hoarders Show Unique Abnormalities
9. Gene Mutation Linked to Facial, Skull Abnormalities
10. Myelodysplastic Syndrome Linked to Abnormal Stem Cells
11. Genome-wide analysis shows previously undetected abnormalities in parents of affected children
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/1/2017)... ... ... After a long period of indulging in holidays, many individuals feel ready ... the detox categories, there is a rare yet successful way to cleanse the lungs ... Detox is an herbal-based formula designed to help cleanse people’s lungs from harmful chemicals ...
(Date:3/1/2017)... , ... March 01, 2017 , ... The Industrial Designers ... 5, 2017 by raising awareness of the profession of industrial design (ID) and relaunching ... content geared toward high school students and counselors; parents; and the greater public. , ...
(Date:3/1/2017)... ... March 01, 2017 , ... ... the release of its 2017 update to Compass, the popular online learning ... advisors. , Suitable for standardizing both new-hire on-boarding and annual competency-validation, Compass ...
(Date:3/1/2017)... ... 2017 , ... Grund® America is proud to announce the new ... March 2017 International Housewares Show in Chicago (Grund Booth N6466). , “We are very ... quality,100% OEKO-TEX and GOTS Organic Cotton material. By adding the GOTS (Global Organic ...
(Date:3/1/2017)... ... March 01, 2017 , ... Granite ... colorectal cancer screening rates by supporting the 80% by 2018 initiative, led by ... and the National Colorectal Cancer Roundtable (an organization co-founded by ACS and CDC). ...
Breaking Medicine News(10 mins):
(Date:3/1/2017)... , March 1, 2017  The Welch Foundation, ... for basic research, today announced that Drs. Neal ... are the 2017 recipients of the Norman Hackerman ... recognized as ,rising stars, having contributed significant scientific discoveries ... first time in the 15 years of the Hackerman ...
(Date:3/1/2017)... , Mar 01, 2017 Research and ... Drugs Price Analysis and Strategies - 2016" report to their ... The ... 2016, provides drug pricing data and benchmarks in the global Acute ... clinical attributes of your competitor drugs and find out how the ...
(Date:3/1/2017)... stesso sistema sara, visibile nello stand a ECR, il Congresso Europeo di Radiologia ... la settima unità MROpen in Gran Bretagna, la prima in Galles. Il sistema ... Cardiff. ESC attualmente gestisce altri due sistemi di risonanza magnetica MROpen a Londra ... ... The open MRI scanner - ...
Breaking Medicine Technology: