Navigation Links
Abnormal brain ultrasounds in premature infants indicate future risk of psychiatric disorders

Infants born prematurely are at risk for injuries to the white and gray matter of the brain that affect cortical development and neural connectivity. Certain forms of these injuries can be detected in the neonatal period using ultrasound, according to Columbia University Medical Center researchers.

Researchers who followed a group of premature infants until age 16 found that those with neonatal ultrasound abnormalities were at increased risk for specific psychiatric disorders, namely, attention deficit hyperactivity, tic disorders, obsessive compulsive disorder, and major depression―all of which are thought to arise from dysfunctions of the subcortical-cortical circuits. The findings were published in the July 2011 issue of the Archives of General Psychiatry.

Premature birth is a growing problem in the United States, adding to the significance of the findings. An increased appreciation of the relation between perinatal brain injuries and later psychiatric disorders could lead to earlier diagnosis and intervention by the pediatricians, psychiatrists, and neurologists who care for these children and adolescents. Future research may also explore the relation of perinatal brain injury to psychiatric disorders, such as schizophrenia, that more commonly come to clinical attention in adulthood

A research group at Columbia University Medical Center/New York State Psychiatric Institute led by Dr. Agnes Whitaker, MD, evaluated more than 400 nondisabled adolescents who had been born prematurely and had had abnormal brain ultrasounds taken at birth. When the researchers administered questionnaires and cognitive tests to the subjects and interviewed their parents, they found a relation between perinatal brain injuries and certain psychiatric disorders at adolescence that could not be explained by other medical or social factors.

Although scientists have speculated for decades that early brain injury can have long-term psychiatric effects, these results provide the first strong empirical evidence of such a relation. "The study," says Whitaker, a clinical professor of psychiatry in the Department of Psychiatry at Columbia University and research psychiatrist in the Division of Child and Adolescent Psychiatry at New York State Psychiatric Institute, "is a beautiful example of interdisciplinary work. The team included researchers from neonatology, pediatrics, psychiatry, and epidemiology. It couldn't have been done otherwise."


Contact: Ann Rae Jonas
Columbia University Medical Center

Related medicine news :

1. New study finds 70 percent of able-bodied hockey players have abnormal hip and pelvis MRIs
2. Autism Consortium study in Pediatrics shows CMA finds more genetic abnormalities than current tests
3. Mount Sinai researchers are the first to identify heart abnormalities in World Trade Center workers
4. Researchers ID brain abnormalities in children exposed to methamphetamine in utero
5. Abnormal Heart Rhythm Linked to Alzheimers
6. High doses of antioxidant supplements induce stem cell genetic abnormalities
7. Visually guided laser may be viable treatment for abnormal heartbeat
8. Cold sore virus may contribute to cognitive and brain abnormalities in schizophrenia
9. Harmless Brain Abnormalities in Kids Pose Disclosure Dilemmas
10. Specially trained nurse practitioner detected same breast abnormalities as surgeon
11. Abnormal brain activity in migraineurs is not restricted to attacks
Post Your Comments:
(Date:11/26/2015)... BOSTON, Mass. (PRWEB) , ... November 26, 2015 ... ... a thorough second medical opinion process, participated in the 61st annual Employee Benefits ... Benefit Plans and took place Sunday, November 8th through Wednesday, November 11th, 2015. ...
(Date:11/25/2015)... ... 2015 , ... As part of a global movement to ... together who want to combine talents and resources to help create sustainable communities ... The non-profit launched its first major fundraiser on November 6, 2015 at Bent ...
(Date:11/25/2015)... NV (PRWEB) , ... November 25, 2015 , ... Dr. ... patients to learn more about hair loss treatment with the Capillus272™ Pro laser therapy ... effective solution for thicker and fuller hair, without the need for surgery, prescription pills, ...
(Date:11/25/2015)... ... 25, 2015 , ... Lakeview Health, a Jacksonville-based drug and ... sobriety and show through pictures what a positive difference it makes. The social ... the hashtag #FacesOfGratitude on their Facebook, Twitter, and Instagram accounts. Short stories ...
(Date:11/25/2015)... ... , ... On November 23rd 2015 Cozy Products, a division of ... Cozy Products explains what this means for business moving forward. , The Tri Lite ... business model: to sell personal heaters that reduce energy consumption, are economical and keep ...
Breaking Medicine News(10 mins):
(Date:11/25/2015)... THOUSAND OAKS, Calif. , Nov. 25, 2015 /PRNewswire/ ... of a Biologics License Application (BLA) with ... Administration (FDA) for ABP 501, a biosimilar candidate to ... the first adalimumab biosimilar application submitted to the FDA ... biosimilar pathway. Sean E. Harper , M.D., ...
(Date:11/25/2015)... , Nov. 25, 2015  Linden Care, LLC, a ... treatment outcomes for patients suffering from chronic pain, said ... a Temporary Restraining Order (TRO) enjoining Express Scripts from ... companies. --> --> ... of its legal options. --> ...
(Date:11/25/2015)... , Nov. 25, 2015 On ... first federal bellwether trial against Wright Medical Technology, ... to their Conserve metal-on-metal hip implant device, awarded ... Following a two week trial and three days ... metal-on-metal hip device was defectively designed and unreasonably ...
Breaking Medicine Technology: