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Abbott's XIENCE V(R) Demonstrates Impressive Low Rates of Repeat Procedure, Stent Thrombosis and Major Adverse Cardiac Events in Complex, 'Real World' Patients in SPIRIT V Study
Date:5/21/2009

re events sets a new standard in real-world studies.

"The low occurrence of repeat procedure and stent thrombosis is noteworthy given that the SPIRIT V study includes high-risk patient groups, including diabetics, patients with multi-vessel disease and patients with highly complex or calcified lesions," said Charles Simonton, M.D., FACC, FSCAI, divisional vice president, Medical Affairs, and chief medical officer, Abbott Vascular. "The outstanding data from SPIRIT V and consistently strong performance of XIENCE V across all clinical trials reinforce why physicians throughout the world have embraced this technology."

Abbott also presented five-year results from the SPIRIT FIRST trial, which was a 60-patient, first-in-man study comparing XIENCE V to the MULTI-LINK VISION(R) Coronary Stent System. XIENCE V continued to demonstrate an excellent long-term safety profile with no MACE or stent thrombosis events between one and five years.

As part of the company's commitment to advancing the treatment of coronary artery disease, Abbott's robust post-approval and continued access program is projected to study more than 20,000 XIENCE V patients across several clinical trials. In addition to SPIRIT V, ongoing studies include:

  • SPIRIT IV, a continued-access trial looking at a more complex patient population in the United States;
  • XIENCE V SPIRIT WOMEN, the world's first drug eluting stent trial to study only female patients will evaluate women in Europe, Asia Pacific, Canada and Latin America;
  • XIENCE V USA, a post-approval study being conducted in the United States; and
  • XIENCE V INDIA, a post-approval study being conducted in India.

Abbott's next-generation drug eluting stent in development, the XIENCE PRIME(TM) Everolimus Eluting Coronary Stent System, utilizes the same drug and polymer as XIE
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SOURCE Abbott
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