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Abbott Statement on ARBITER 6 - HALTS Results and Abbott's Niaspan (niacin extended-release)
Date:11/15/2009

een shown to slow down or reduce atherosclerosis, the hardening of coronary arteries due to plaque build-up. NIASPAN has not been shown to prevent the development of heart disease.

Important Safety Information About NIASPAN

NIASPAN is contraindicated in patients with liver problems, stomach ulcers, or serious bleeding problems; and those allergic to any product ingredient. NIASPAN is the only prescription extended-release form of niacin. Liver damage has been reported when NIASPAN has been substituted for equivalent doses of immediate-release niacin.

Patients should check with their healthcare provider before changing their medication. NIASPAN should be used with caution in patients who consume large amounts of alcohol. Blood tests may be performed before and during treatment with NIASPAN to check for liver problems. Patients treated with NIASPAN in combination with a statin should be monitored for any unusual muscle pain, tenderness, or weakness, as this could be a sign of a rare but serious side effect. Diabetic patients should be observed closely as NIASPAN may cause a dose-related increase in blood sugar levels. Flushing (warmth, redness, itching, and/or tingling of the skin) is the most common side effect. This sensation usually occurs when starting NIASPAN or during dose increases and may become less frequent over time. In most patients, flushing is mild to moderate. Some people may experience more severe and intense flushing. Additional symptoms may include rapid or pronounced heartbeat, shortness of breath, swelling, sweating, chills, dizziness, and in rare cases, fainting. NIASPAN should be used with caution in patients with a history of gout or kidney problems. Some medicines should not be taken with NIASPAN. Patients should tell their healthcare provider about all the medicines they take. Other common side effects with NIASPAN may include headache, pain, diarrhea, indigestion, nausea, vomiting, itchi
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