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ATS issues statement on the treatment of pulmonary fungal infections
Date:1/3/2011

The American Thoracic Society has released a new official clinical policy statement on the treatment of fungal infections in adult pulmonary and critical care patients. The statement replaces ATS guidelines published in 1988, and takes into account new medications and treatment approaches, as well as provides an overview of emerging fungi.

The statement appears in the January 1, 2011, issue of the American Journal of Respiratory and Critical Care Medicine.

Pulmonary fungal infections occur commonly in patients whose immune systems are compromised, either by an underlying disease or illness or through the use of immune-suppressing medications, often prescribed following organ transplantation or to treatment for an autoimmune disorder, such as lupus or rheumatoid arthritis. The number of diagnosed pulmonary fungal infections has grown significantly in the past decade, and diagnostic methods and treatment options have also expanded, making the need for new guidelines especially critical.

"The incidence, diagnosis, and clinical severity of pulmonary fungal infections have dramatically increased in recent years in response to a number of factors," said Andrew Limper, MD, Professor and Chair of Pulmonary Medicine at Mayo Clinic and Chair of the ATS Fungal Infections Working Group. "In addition to growing numbers of immune-compromised patients with HIV and other diseases, the number of patients receiving drugs to suppress the immune system following organ transplant or as the result of autoimmune inflammatory conditions has also increased."

Advances in diagnostic techniques, including the use of computed tomography (CT), positron emission tomography (PET) scans, bronchoscopy, mediastinoscopy and video-assisted thoascopic biopsy, have also allowed physicians to accurately identify increasing numbers of pulmonary fungal infections, Dr. Limper noted.

"At the same time, the introduction of new medications has significan
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Contact: Brian Kell
bkell@thoracic.org
212-315-6442
American Thoracic Society
Source:Eurekalert

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