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ATS issues report on emerging issues in HIV-associated pulmonary disease
Date:3/3/2011

The American Thoracic Society has released a new report detailing recent global changes in the management of human immunodeficiency virus (HIV)-associated pulmonary disease. The report examines the evolving landscape of HIV and its associated diseases in areas where combination antiretroviral therapies (ART) are available, as well as offering insight into the trends occurring in areas of the world where ART use is limited.

The report appears in the March 1, 2011, issue of the Proceedings of the American Thoracic Society.

Since it first came to the public eye in the early 1980s, HIV infection has caused an estimated 25 million deaths worldwide. Patients whose immune systems are weakened by HIV infection historically have been prone to acute lung diseases and infections, most notably tuberculosis (TB) and pneumonia. However, with the introduction of combination antiretroviral therapy (ART) there has been a shift toward more chronic lung diseases among HIV-infected patients in countries where ART is widely available.

Because of the importance of HIV-associated pulmonary diseases and the rapidly evolving knowledge about their development and epidemiology, the American Thoracic Society convened a workshop to discuss current and emerging trends and issued a report based on those findings.

"In the early, pre-ART years of the HIV epidemic, pulmonary infections such as Pneumocystis pneumonia (PCP), TB and bacterial pneumonia were the most frequent pulmonary complications among HIV patients," said Alison Morris, MD, associate professor of medicine and immunology, Division of Pulmonary, Allergy and Critical Care Medicine at the University of Pittsburgh School of Medicine. "Currently, infectious diseases are less common, although still prevalent, and diseases such as emphysema, pulmonary arterial hypertension (PAH) and lung cancer appear to be increasing. New syndromes associated with ART have also become important.

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Contact: Brian Kell
bkell@thoracic.org
212-315-8442
American Thoracic Society
Source:Eurekalert

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