Navigation Links
ASTRO publishes palliative radiotherapy for bone metastases guideline

The American Society for Radiation Oncology (ASTRO) Clinical Affairs and Quality Committee has developed a guideline for the use of radiation therapy in treating bone metastases. The guideline will be published in the International Journal of Radiation OncologyBiologyPhysics, an official journal of ASTRO.

Bone metastases are caused when a malignant tumor spreads to the bone. They can lead to debilitating effects including pain, fractures and paralysis due to spinal cord compression. The care of these patients requires collaboration between several types of cancer treatment specialists.

External beam radiation therapy (EBRT) provides successful pain relief in 50 to 80 percent of patients with little risk of side effects. However, the widespread variation in practice patterns between radiation oncologists presented an opportunity to standardize care through the construction of a formal treatment guideline.

Some of the committee's findings include:

  1. EBRT continues to be the mainstay for treating bone metastases.

  2. Both single doses and longer courses of radiation have shown similar pain relief outcomes, and each has advantages. A single course has proven more convenient for patients and caregivers, while longer courses have a lower incidence of repeat treatment to the same site.

  3. Repeat irradiation with EBRT might be feasible in some circumstances, though the details of its effectiveness and safety are still to be determined.

  4. Bisphosphonates do not eliminate the need for EBRT for painful metastases, and they act effectively when combined with EBRT.

  5. Stereotactic body radiation therapy can be considered for patients with a newly discovered or recurrent tumor in the spinal column or paraspinal areas; however, it is suggested that stereotactic treatment be reserved for patients who meet specific criteria, who are treated at centers with sufficient training and experience, and who are part of a therapeutic trial.

  6. Radionuclides are most appropriate for patients who have several sites of painful osteoblastic metastases (like those that are commonly associated with prostate cancer) that cannot be conveniently or safely treated with EBRT.

  7. Surgical decompression and stabilization plus postoperative radiation therapy should be considered for some patients with single-level spinal cord compression or spinal instability.

    Stephen Lutz, M.D., lead author of the guideline and a radiation oncologist at Blanchard Valley Regional Cancer Center in Findlay, Ohio, said, "Radiation therapy is commonly used to treat bone metastases and has been proven very effective, but with the variety of radiation therapies available and range of successful fractionation schedules, it's important to provide physicians with this guideline to assure they are using the most appropriate methods in treating patients."


Contact: Beth Bukata
American Society for Radiation Oncology

Related medicine news :

1. Senate Committee Advances Disastrous Idaho Health Freedom Act
2. ReportsandReports : The Gastrointestinal Market Outlook to 2014: Market Dynamics, Competitive Landscape, Emerging Therapies
3. ASTRO awards 17 Advocacy Day travel grants
4. ASTRO publishes supplement on protecting cancer patients by reducing radiation doses, side effects
5. Santa Monica Jury Rejects Claims of Catastrophic Brain Injury From Exposure to Mold; Plaintiff Faces Motions for Attorney Fees and Costs
6. Astrogenetix Narrows in on MRSA Virulence Onboard Discovery
7. A new endoscopic technique for gastrointestinal perforations: the over-the-scope-clip
8. ASTRO president speaks on prostate cancer at MEDCAC meeting
9. ASTRO applauds nomination of Dr. Donald Berwick to head Centers for Medicare and Medicaid Services
10. Outstanding young gastroenterologists receive AGA Foundation
11. Outstanding young gastroenterologists receive AGA Foundation 2010 Research Scholars Award
Post Your Comments:
(Date:10/12/2017)... ... October 12, 2017 , ... First Healthcare Compliance (FHC), an ... showcase a range of technology and learning solutions at the 68th Annual American ... to be held October 14–18, 2017 at the Mandalay Bay Resort in Las ...
(Date:10/12/2017)... ... October 12, 2017 , ... IsoComforter, Inc. ( ), one ... an innovative new design of the shoulder pad. The shoulder pad provides optimal ... controlling your pain while using cold therapy. By utilizing ice and water that is ...
(Date:10/12/2017)... ... October 12, 2017 , ... Dr. Parsa Mohebi, ... a medical article to the newly revamped Cosmetic Town journal section, ... hair transplant procedure known as Follicular Unit Extraction (FUE). , Dr. ...
(Date:10/12/2017)... ... October 12, 2017 , ... ... one of Michigan’s 2017 Best and Brightest in Wellness® by Best and Brightest. ... awards program on Friday, Oct. 20 from 7:30 a.m. to 2 p.m. at ...
(Date:10/12/2017)... , ... October 12, 2017 , ... ... at the University of California Berkeley, and other leading institutions in announcing the ... power of institutions to change the way animals are raised for food. , ...
Breaking Medicine News(10 mins):
(Date:10/12/2017)... Divoti USA will engrave and process all non-coated ... latest FDA requirements, which stipulates new criteria regarding medical device manufacture ... Medical ID jewelry such as Medical ID Bracelets, can rest assured ... of the new FDA requirements . ... Divoti offers this dark mark fiber laser engraving process ...
(Date:10/11/2017)... Oct. 11, 2017  BioPharmX Corporation (NYSE MKT: BPMX) ... developed an innovative way to use nonlinear optical imaging ... of new drugs. ... Conference will show how researchers from BioPharmX and the ... School used a suite of imaging techniques in what ...
(Date:10/11/2017)...  True Health, a leader in integrated diagnostics ... National Breast Cancer Awareness month to educate doctors ... Research recently published in ... than 10 million American women are at significant ... BRCA2 and have not had testing. These mutations can ...
Breaking Medicine Technology: