Navigation Links
ASTRO: Deviating from radiation protocols increases risk of treatment failure and death
Date:10/30/2012

PHILADELPHIA--Implementing measures to ensure radiation therapy protocols are followed not only decreases deviations, but it can also improve overall survival in cancer patients, Thomas Jefferson University Hospital researchers suggest in a first-of-its kind study presented during a plenary session at the American Society for Radiation Oncology (ASTRO) 54th Annual Meeting in Boston.

Researchers from the Department of Radiation Oncology at Jefferson analyzed radiation therapy protocols, quality assurance (QA) measures and patient outcomes in eight, large clinical trials to determine if such deviations were associated with inferior clinical outcomes.

The findings, presented by Nitin Ohri, M.D., who conducted the research while at Jefferson, but is currently at Albert Einstein/Montefiore Medical Center in New York., revealed that deviating from protocols was associated with up to a 75 percent increased risk of treatment failure and overall mortality. This suggests that implementing QA measures to ensure protocols are followed could improve outcomes for cancer patients, according to the authors.

It is widely accepted that deviating from a radiation therapy protocol in a clinical trial will more than likely result in adverse effects. And, as a result, significant QA measures have been taken over the last several decades to minimize such effects. However, while these measures have shown to decrease deviation, there is currently no data establishing the patient-outcome benefits of those measures. This is the first study, to the author's knowledge, to examine the effects on those measures on risk of treatment failures and mortality.

Examples of radiation therapy deviation include inadequate targeting of high-risk lymph node regions or incorrect dose calculation.


'/>"/>
Contact: Steve Graff
stephen.graff@jefferson.edu
215-955-5291
Thomas Jefferson University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. Radiation treatment after surgery improves survival for elderly women with early-stage breast cancer
2. Many Mistakenly Think Radiation Might Cure Terminal Lung Cancer
3. Study: No Long-Term Heart Risks From Breast Radiation
4. Mayo Clinic: Antidepressant eases radiation-related mouth pain in head, neck cancer
5. Minorities most likely to have aggressive tumors, less likely to get radiation
6. Fasting makes brain tumors more vulnerable to radiation therapy
7. Stage I NSCLC patients who receive radiation therapy are surviving longer
8. Brain radiation after lung cancer treatment reduces risk of cancer spreading
9. Stem-cell-protecting drug could prevent the harmful side effects of radiation therapy
10. Face-Down Position May Be Safer During Radiation for Breast Cancer: Study
11. Use of regional PACS network associated with lower repeat rates, costs and less radiation exposure
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/24/2014)... July 24, 2014 Memantine was initially developed ... marketed in Germany under the brand name Akatinol; it was ... as Ebixa and in the USA to Forest Labs as ... million in 2013. In the US, Forest reported Namenda sales ... expiry in Canada, Australia and the European region has increased ...
(Date:7/24/2014)... July 24, 2014 As the age ... to egg freezing as a way to ensure future ... otherwise decline with advancing reproductive age. Vitrification technology, a ... cutting edge medical technology that allows a woman to ... peak fertility years, which are then stored for future ...
(Date:7/24/2014)... with high-throughput data generated by breast cancer biologists ... computational method to determine how gene networks are ... as they respond to potential cancer therapy agents., ... each other in laboratory-grown cells is described in ... PLOS Computational Biology . , The method ...
(Date:7/24/2014)... In a recent report by CBS News, the district ... to criminal penalties associated with possession of small amounts of ... in Washington DC, giving it one of the most tolerant ... for possession of one ounce of marijuana or less with ... than an ounce of marijuana remain criminal offenses under the ...
(Date:7/24/2014)... from Penn Medicine shows that incisionless transcatheter aortic ... stay by 30 percent and has no impact ... conventional transfemoral TAVR, which requires an incision in ... the current issue of Circulation: Cardiovascular Interventions ... aortic valve without a traditional open-heart surgical approach. ...
Breaking Medicine News(10 mins):Health News:Memantine Discussed in New Comprehensive Patent Search Report by Ark Patent Intelligence Published at MarketPublishers.com 2Health News:Memantine Discussed in New Comprehensive Patent Search Report by Ark Patent Intelligence Published at MarketPublishers.com 3Health News:Expanded Financial Options for Women Interested in Proactive Egg Freezing at Shady Grove Fertility 2Health News:Expanded Financial Options for Women Interested in Proactive Egg Freezing at Shady Grove Fertility 3Health News:Expanded Financial Options for Women Interested in Proactive Egg Freezing at Shady Grove Fertility 4Health News:Gene changes in breast cancer cells pinpointed with new computational method 2Health News:Gene changes in breast cancer cells pinpointed with new computational method 3Health News:Washington D.C. Decriminalizes Marijuana 2Health News:Penn study: Incisionless transcatheter aortic valve replacement surgery cuts hospital length of stay 2
... treating severe and complex wounds in children that decreases the ... in Wound Repair and Regeneration shows that this technique has ... life-saving. ,“This wound therapy is usually delivered via ... wound base through a sponge sealed to the wound by ...
... Journal of Gastroenterology suggests that smoking may determine which ... who suffer from Crohn’s disease. Where the disease is ... surgical treatment. ,“In patients who smoke, Crohn’s ... intestine, rather than the colon,” says study author Dr. ...
... been recommended for medical conditions such as endometriosis, but ... for women who dislike menstruation or find it inconvenient. ... is it a reasonable lifestyle choice, asks Paula Derry, ... ,Birth control options that reduce or eliminate periods are ...
... can be highly addictive, warn two doctors in this week’s ... drugs is often forgotten, write Drs Chris Ford and Beth ... three patients with addictions to Nurofen plus (ibuprofen and codeine ... for its approved indications, but their use had escalated as ...
... bad news for older women who like their meat smoked or ... that post-menopausal women who consumed the most grilled, barbecued or smoked ... of breast cancer. Big meat-eaters who also skimped on fruit and ... scientists led by Dr. Susan E. Steck of the University of ...
... of America will hold a hearing on a neglected yet, crucial ... In America, one in three children do not have ... 25 million.,As for Medicaid, with the poorest children this is of ... its low reimbursement rates. , Lack of dental insurance, ...
Cached Medicine News:Health News:Should Menstrual Suppression Be a Lifestyle Choice? 2Health News:Barbeque Lovers Warned To Load On Fruits And Vegetables 2Health News:More Than a Toothache 2
(Date:7/24/2014)... July 24, 2014  Restore Health, a leading ... pharmaceuticals, announced that it is now offering pharmacogenetics ... each individual based upon their particular genetic makeup. ... the interaction between a patient,s genetics and their ... excited to provide this new service to healthcare ...
(Date:7/24/2014)... CITY, Calif., July 24, 2014  Abaxis, Inc. (NasdaqGS: ... point-of-care blood analysis systems, today reported financial results for ... First quarter overview: , Revenues of $47.5 ... , Diluted EPS of $0.21, up 50% over last ... Medical market revenues of $7.2 million, up 20% over ...
(Date:7/24/2014)... MOUNTAIN VIEW, Calif. , July 24, 2014 ... ), a leading provider of medication and supply ... hold a conference call Thursday, July 31, to ... What:  , Omnicell Second Quarter 2014 earnings ... 2014, 1:30 p.m. PTWho:  , Randall Lipps, chairman, ...
Breaking Medicine Technology:Restore Health Launches Pharmacogenetic Testing, Enhancing Its Suite of Personalized Medicine Goods and Services 2Restore Health Launches Pharmacogenetic Testing, Enhancing Its Suite of Personalized Medicine Goods and Services 3Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 2Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 3Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 4Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 5Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 6Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 7Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 8Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 9Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 10Abaxis Reports Financial Performance for the First Quarter of Fiscal 2015 11Omnicell to Release Second Quarter 2014 Earnings Results on July 31 2
... N.Y., Oct. 19 AccuVein LLC today announced a ... pharmaceutical and medical devices distribution company, providing the AccuVein ... to customers in Greece, Spain and Portugal. The AccuVein ... IV infusion and blood donation by projecting a pattern ...
... Pharmaceutical Research and Manufacturers of America (PhRMA) ... statement today regarding appropriate incentives for continued biotechnology ... healthcare providers, and elected leaders at the state ... responsible, abbreviated approval pathway for biosimilars that includes ...
Cached Medicine Technology:AccuVein Signs Multiple-Country Distribution Agreement in Europe for Vein Illumination Device 2PhRMA Statement Supporting Fair Incentives for Biologics Innovation 2PhRMA Statement Supporting Fair Incentives for Biologics Innovation 3PhRMA Statement Supporting Fair Incentives for Biologics Innovation 4PhRMA Statement Supporting Fair Incentives for Biologics Innovation 5
The Accuref 8001 allows you to measure much smaller pupils than conventional units and 3 step Target light adjuster ensures accurate results....
... is an Auto Refractor/Keratometer with ... refinement. Electronic elevation, automatic alignment, ... accuracy and all the other ... Marco Automatic Refractors/Keratometer famous, make ...
Sterile perfluorocarbon for intraocular Application....
Sterile Silicone Oil for Intraocular Application....
Medicine Products: