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ASCO honors Ching-Hon Pui, M.D., for work advancing childhood cancer research and treatment
Date:3/21/2012

(MEMPHIS, Tenn. March 20, 2012) Ching-Hon Pui, M.D., a renowned leader in the research and treatment of childhood leukemia, is the recipient of the 2012 Pediatric Oncology Award from the American Society of Clinical Oncology (ASCO). The honor recognizes Pui's many contributions to better understanding the blood cancer's biology and treatment as well as his role in improving leukemia survival rates.

Pui will receive the award in June at the 2012 ASCO Annual Meeting in Chicago. He will also present a talk on the possibility of achieving total cure of childhood acute lymphoblastic leukemia (ALL) with personalized therapy.

"This recognition is a fitting tribute to Dr. Pui's life work and his tireless fight against pediatric leukemia," said Dr. William E. Evans, St. Jude director and CEO. "He is an encyclopedia of knowledge that physicians and scientists around the world call upon every day, and he works literally around the clock to expand our knowledge of childhood leukemias and how to better treat them in the future."

Pui has devoted 30 years to the fight against childhood cancer and is credited for innovations that have driven cure rates for pediatric leukemia to unprecedented heights. Implementing pharmacodynamics and pharmacogenetics to individualize chemotherapy and to optimize the use of existing drugs, Pui and colleagues have achieved cure rates of 90 percent at St. Jude for pediatric ALL, the most common childhood cancer.

The personalized therapy approach has allowed clinicians to discontinue the use of cranial irradiation in treatment of this disease, thus sparing children from many devastating long-term side effects. This approach also resulted in a remarkably high cure rate for older adolescents with ALL, who historically fared far worse than their younger counterparts with the disease.

Pui and colleagues also made inroads in understanding the pathogenesis of leukemia and in identifying mechanisms of d
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Contact: Carrie Strehlau
carrie.strehlau@stjude.org
901-595-2295
St. Jude Children's Research Hospital
Source:Eurekalert

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