Navigation Links
ASCO: Glioblastoma in the 21st century: Wealthier patients living longer than poorer patients
Date:6/2/2011

Survival rates of wealthier patients and those younger than 70 with glioblastoma, the most common and aggressive malignant brain tumor, have improved since 2000, whereas rates for those living in poorer areas and older than 70 have remained stagnant, according to an abstract being presented at the American Society of Clinical Oncology annual meeting in Chicago by Thomas Jefferson University Hospital researchers on Saturday, June 4. (ABSTRACT #6089).

The addition of concurrent and adjuvant temozolomide, a chemotherapy drug also referred to as TMZ, to post-operative radiation therapy has been shown to improve overall survival in randomized trials for patients younger than 70, but it was unknown if this benefit translated down to the population-based level.

To answer this, researchers performed a population-based survival analysis of newly diagnosed glioblastoma patients (from 2000 to 2007) covering the period before and after the introduction of temozolomide. They further analyzed the impact of mean regional income on any improvements in overall survival during this time period.

Survival statistics and pertinent clinical and demographic variables were extracted from the Survival, Epidemiology and End Results (SEER) Database for patients diagnosed. Patients were divided into income quartiles based on mean household income in their county of residence.

From 2001 to 2007, the median survival time increased from 7 to 9 months for the entire population. One-year survival rate increased from 29 percent to 39 percent.

Outcomes in patients older than 70 years did not improve over this period, even amongst patients who had gross total resection and radiation therapy. Over the study period, the absolute disparity in one-year survival between economically poor-and-affluent areas increased from 6.6 percent to 10.1 percent.

"The management of patients with g
'/>"/>

Contact: Steve Graff
stephen.graff@jefferson.edu
215-512-1783
Thomas Jefferson University
Source:Eurekalert

Page: 1 2

Related medicine news :

1. ASCO: Emerging trends in radiation therapy for women over 70 with early stage breast cancer
2. Professor Zvi Ram presents phase III recurrent glioblastoma survival and quality of life data from the first pivotal study of the NovoTTF-100A at 15th Annual Society for Neuro-Oncology Scientific Meeting
3. Vaccine extends glioblastoma patients survival in phase II trial
4. Multidisciplinary treatment of glioblastoma multiforme can extend patients life
5. Hospice Care More Common in Wealthier Areas, Study Finds
6. U of Alberta researchers hoping to stop heart disease in cancer patients before it starts
7. Two-thirds of newly diagnosed cancer patients unable to obtain oncology appointments
8. Lymphocyte count indicates the prognosis of patients with renal cell carcinoma
9. Less toxic combination of erlotinib and bevacizumab is effective non-small cell lung cancer patients
10. Re-admission rates via emergency rooms climbing among patients who have recently been hospitalized
11. Mayo Clinic finds discussion of end-of-life care helps heart to patients and families
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/28/2015)... 2015 Take a bite of warm, ... action. Acids tumble into the stomach, ready to break ... structure lets these acids run amok, triggering a burning ... symptom. More than 60 million Americans have heartburn at ... heartburn starts, and how it can be stopped. , ...
(Date:3/28/2015)... 2015 The California-based leading wig brand ... customer shopping on UniWigs during the Easter Holidays from ... big promotion on April Fools’ Day. , As the ... around the corner. Easter Festival, with religious origins to ... major holiday after Christmas. The best wig provider, UniWigs, ...
(Date:3/28/2015)... 2015 An article in Fortune on ... prove critical to organizations that deal with PCI (Payment ... of data security, is worsening . Using numbers ... every major category out of the twelve measured improved, ... all the craziness that has gone on in the ...
(Date:3/28/2015)... Vegas, NV (PRWEB) March 28, 2015 ... experiences re-injury, according to research presented today at the ... Specialty Day. The study examined the long term success ... , “We examined survey data from 242 patients ... lead author Justin P. Roe, MBBS, FRACS, from North ...
(Date:3/28/2015)... Early surgery may not be the best ... injuries, according to new research from Tripler Army Medical ... Society for Sports Medicine’s ( AOSSM ) Specialty Day, ... was not performed. , The final study group focused ... 17 receiving non-surgical therapy. Of the non-surgery group, 8 ...
Breaking Medicine News(10 mins):Health News:Bypass Your Heartburn Worries This Easter With Tylers Coffee 2Health News:UniWigs Is Sending Out Mysterious Gifts During the Easter Holidays 2Health News:Businesses Dealing With PCI Falling Short On Regular Vulnerability Scans and Pen Testing 2Health News:Businesses Dealing With PCI Falling Short On Regular Vulnerability Scans and Pen Testing 3Health News:Businesses Dealing With PCI Falling Short On Regular Vulnerability Scans and Pen Testing 4Health News:Young Athletes at Greater Risk for Re-Injury after ACL Surgery 2Health News:For Type V AC Joint Injuries, Early Surgery May Not Be the Best Approach 2
... medication and reduce risk of ... medication errors, ... move to continually improve patient safety,and staff efficiency, Omnicell, Inc. (Nasdaq: ... facilities, and Grant Regional Health,Center, a leading healthcare provider, today announced ...
... the,appointment of Bryan R. Rogers as President of HCA,s ... Jan. 1, 2008. Rogers replaces Tom,May who recently announced ... will have responsibility for,operations in Nevada, California and Alaska, ... with annual net revenues of,$2.5 billion. He currently ...
... Lead Life Insurance Wholesaling to Company,s Retail Distribution ... Kahal has joined AXA,Equitable as National Sales Manager ... CT. The announcement was made,today by Jamie Shepherdson, ... and annuity wholesale distribution organization. Mr. Kahal,will report ...
... Researchers at the American University of ... that administering a lidocaine lollipop as a single-agent ... endoscopy procedure eliminated the need for sedation in ... in the October issue of Gastrointestinal Endoscopy, the ...
... who couple classroom courses with behind-the-wheel training can significantly ... in the latest issue of The Journal of ... A recent study spearheaded by Yale University,s Richard Marottoli ... underwent eight hours of classroom instruction and two hours ...
... Global Med Technologies(R),Inc. (OTC Bulletin Board: GLOB), ... that it will report its,third quarter results on ... Company will host a conference call at 4:30 ... http://www.newscom.com/cgi-bin/prnh/20040226/GLOBALMEDLOGO ) Conference Call Details: ...
Cached Medicine News:Health News:Grant Regional Health Center Increases Patient Safety and Pharmacy Efficiency with Omnicell Medication Use Systems 2Health News:Grant Regional Health Center Increases Patient Safety and Pharmacy Efficiency with Omnicell Medication Use Systems 3Health News:Bryan R. Rogers Appointed President of Far West Division 2Health News:David Kahal Joins AXA Equitable as National Sales Manager 2Health News:Patients may have sweet and effective way to prepare for upper GI endoscopy: an anesthetic lollipop 2Health News:Patients may have sweet and effective way to prepare for upper GI endoscopy: an anesthetic lollipop 3Health News:Global Med Technologies(R) Inc. to Announce Third Quarter Results On October 30th - Conference Call to Follow Release 2
(Date:3/27/2015)... WASHINGTON , March 27, 2015 ... - The biopharmaceutical industry comes out on top as ... in a new report  from ndp│analytics. According to ... and development (R&D) investment over the last decade, accounting ... 2000-2012. A Short Video on ...
(Date:3/27/2015)... The Temple Health & Bioscience District (THBD) today ... at 1802 South First St. in the Temple Medical and ... City of Temple to receive funding for ... Texas Veterans Health Care System, the new facility will enable ... biotechnology and life science companies. ...
(Date:3/27/2015)... , March 27, 2015 A new report ... Latin America – Chile , ... are top targets for IVD firms.  The healthcare research ... heavily into IVD strategies for the Latin American continent with ... support globally distributed supply operations. However, the country,s regional economic ...
Breaking Medicine Technology:Week in Review: The Latest from PhRMA 2Temple Health & Bioscience District Relocates, Offers Office And Lab Space To Biotech Companies 2Kalorama: Beyond Brazil, Latin American IVD Market Grows 2Kalorama: Beyond Brazil, Latin American IVD Market Grows 3Kalorama: Beyond Brazil, Latin American IVD Market Grows 4
... SAN DIEGO, Nov. 16 CareFusion (NYSE: ... announced a Web-based application that provides hospitals with on-demand ... costs. , The CareFusion Knowledge Portal is a remotely ... information dashboard to review metrics and actionable data directly ...
... Nov. 16 Personalized Pharmaceutical Systems (PPS) today announced ... Viropharma Incorporated. , PPS is a clinical trial ... technology in phenomics to help drug companies identify the ... help patients get the right drug the first time. ...
Cached Medicine Technology:CareFusion Launches Knowledge Portal to Provide Actionable Information Across Product Platforms 2CareFusion Launches Knowledge Portal to Provide Actionable Information Across Product Platforms 3Personalized Pharmaceutical Systems Announces Sale of Angioedema Clinical Prediction Guide to Viropharma Incorporated 2
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
Medicine Products: