Navigation Links
ARUP Laboratories' Scientist Tanya Sandrock Receives NIH Grant to Search for Additional HIV Therapies
Date:9/9/2009

SALT LAKE CITY, Sept. 9 /PRNewswire/ -- ARUP Laboratories, a national clinical and anatomic pathology reference laboratory and a leader in innovative laboratory research and development, announced that ARUP's Tanya Sandrock, PhD, Research & Development scientist, received a prestigious National Institutes of Health (NIH) grant to research additional HIV therapies. Sandrock also serves as chief scientific officer of Integratech Proteomics, a University of Utah start-up company focused on developing new peptide and small-molecule therapeutics with activity against HIV integrase, an enzyme with an essential function in the retroviral replication cycle.

The NIH grant received by Sandrock aims to obtain a small molecule that mimics the effects of an HIV integrase peptide inhibitor. "Forty million people are estimated to be infected with HIV/AIDS worldwide, and 22 million people have died since the discovery of the virus in the 1980s," explained Sandrock. "Drugs that inhibit reverse transcriptase, protease, and integrase are available, but drug side effects and viral resistance have made it necessary to develop new treatments for HIV/AIDS. The inhibitory peptide, in conjunction with yeast two-hybrid technology, may result in the discovery of new INT inhibitory compounds to integrase."

Sandrock's research aims to optimize target-peptide displacement assays; screen chemical libraries under high throughput conditions for compounds that disrupt peptide-HIV integrase interaction in yeast; and select the best small-molecular weight drug candidates for further optimization.

ARUP will provide Integratech Proteomics with access to a wet lab and equipment through its incubator program, which allows research and development activities to take place on-site.

"ARUP is fully committed to maintaining its role as a training and research laboratory of the University of Utah School of Medicine," said ARUP Laboratories' President and CEO Edward Ashwood, MD. "ARUP enthusiastically supports Dr. Sandrock in her research efforts. Her persistence in pursuit of a new HIV therapeutic has been impressive. Even though AIDS has been checked by the development of drugs that target the virus, more drugs are needed to control the worldwide spread of this infection."

Integratech Proteomics benefited from a new program called Venture Bench, created by the Technology Commercialization Office (TCO) at the University of Utah, to assist university start-ups with infrastructure support. Danuta Petelenz, TCO business manager, said, "This is exactly the type of company the university is interested in assisting and starting, one that provides the possibility of a life-changing solution for a deadly disease and complements the strengths of the life-science capabilities at the University of Utah."

Integratech Proteomics will consider peptide therapy in addition to the small-molecule approach. Sandrock will examine novel nano-technology for drug delivery and will continue collaborating with the NIH, ARUP Laboratories, and the University of Utah to expand knowledge of HIV biology.

About ARUP Laboratories

ARUP Laboratories is a national clinical and anatomic pathology reference laboratory and an enterprise of the University of Utah and its Department of Pathology. ARUP offers over 2,000 tests and test combinations, ranging from routine screening tests to highly esoteric molecular and genetic assays, for patients nationwide. ARUP is a worldwide leader in innovative laboratory research and development. Further information on ARUP Laboratories can be found at www.aruplab.com.


'/>"/>
SOURCE ARUP Laboratories
Copyright©2009 PR Newswire.
All rights reserved

Related medicine news :

1. Caraco Pharmaceutical Laboratories, Ltd. Announces FDA Approval to Market Generic Version of Zyloprim(R)
2. Caraco Pharmaceutical Laboratories, Ltd. Announces FDA Approval to Market Generic Version of Adipex-P(R)
3. Planet Technologies Announces Agreement to Acquire Antigen Laboratories
4. Caraco Pharmaceutical Laboratories, Ltd. Announces FDA Approval to Market Generic Version of Coreg(R)
5. Sandia National Laboratories Selects Allscripts Electronic Health Record and Practice Management for Employee Health Center
6. Andrew Lessmans TWC Construction and ProCaps Laboratories Contract With DT Solar to Install a 700 kW Solar Electric System
7. Mesa Laboratories Names New Vice President of Sales and Marketing
8. Caraco Pharmaceutical Laboratories Ltd. Announces Tentative FDA Approval for Generic Zyrtec Chewable(R)
9. Forest Laboratories, Inc. Sets Date and Conference Call for Fiscal 2008 Second Quarter Earnings
10. Roxane Laboratories, Inc. Announces the Launch of Oxcarbazepine Tablets, 150mg, 300mg and 600mg
11. JDRF partners with Housey Pharmaceutical Research Laboratories
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:2/24/2017)... ... ... The International Association of Eating Disorders Professionals (iaedp) announces the 2017 top five ... art competition. Selected from 15 submissions from around the nation, the top five finalists ... iaedp Symposium, March 22 – 26 in Las Vegas. , This year, the competition ...
(Date:2/24/2017)... , ... February 24, 2017 , ... The Radiology ... excellence in radiology marketing programs at the annual Building Better Radiology Marketing Programs ... Fort Worth Hotel in Fort Worth, Texas. Nine awards are given out in five ...
(Date:2/24/2017)... ... February 24, 2017 , ... Congratulations ... International Elite division on February 12th. Ms. Esparza qualified into this prestigious ... qualifier competition held in Las Vegas, Nevada. Frida is one of approximately 25 ...
(Date:2/23/2017)... ... February 23, 2017 , ... Thinksport, the ... The Jensie Gran Fondo of Marin. For the second year in a row, ... mineral-based sunscreen. , “We are thrilled to provide our safe, non-toxic sunscreen to ...
(Date:2/23/2017)... (PRWEB) , ... February 23, 2017 , ... The 89th ... the winner of the 2016 National Education Policy Center Bunkum Award. We invite you ... in 2016. , This year’s Bunkum winner is the Center for American Progress (CAP), ...
Breaking Medicine News(10 mins):
(Date:2/24/2017)... , Australien, 24. Februar 2017 ITL ... Unternehmen des Gesundheitsbereiches, ist erfreut, für das zum ... dem entsprechenden Vorjahreszeitraum exzellente Ergebnisse vorlegen zu können. ... Aktualisierung zum Wachstum" finden Sie hier . ... Gewinn nach Steuern 2,12 Millionen USD (Dez. 2015: 1,04 Millionen USD; +104 %) ...
(Date:2/24/2017)...  The particle counters market is projected to ... 275.9 million in 2016, at a CAGR of ... http://www.reportlinker.com/p04718602-summary/view-report.html The growing pharmaceutical and ... growth in manufacturing industries in emerging nations are ... counters. On the other hand, technical limitations of ...
(Date:2/23/2017)... , Feb 23, 2017 Research and Markets ... Price Analysis and Strategies - 2016" report to their offering. ... The latest ... provides drug pricing data and benchmarks in the global Autism Spectrum ... What are the key drugs marketed for Autism ...
Breaking Medicine Technology: