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AMAS Test Measures Lethal Replikin Gene Activity in Lung and Other Cancers
Date:12/6/2007

d during outbreaks. Strain-specific increases in replikin count have appeared in relation to the major influenza pandemics and epidemics, after years of constant low stable counts. Furthermore, a high replikin count of the RPG of an organism has been shown to be associated consistently with a higher percent lethality in the host. The increase in count was frequently detected one year or more before the outbreak was clinically apparent. The ability to identify, count and track replikins in the genomic structure of an emerging organism has been shown to be accurately predictive in advance warning of H5N1 outbreaks, and may have value in the management of influenza epidemics.

The highest replikin count of the RPG found in any organism studied to date is in lethal non-small cell lung cancer. The highest AMAS test results found to date also are in lung cancer. Tobacco mosaic virus has some sequences in its RPG that are identical to those in the RPG in non-small cell carcinoma of the lung. Two structural studies have suggested mobility and inter-organism transfer of replikins associated with lethality.

Replikins have been chemically synthesized and were found experimentally to be immunostimulants, producing strong antibody responses in animals. Synthetic cancer replikins administered to animals produce antibodies that can be measured by the AMAS cancer test. The AMAS test's results are evidently related to the rate of replication in the cancer. In short, the AMAS test measures the activity of the replikins that are unique to cancers, whose concentration is related to lethality.

High replikin counts are present in a wide range of lethal diseases. The structural and functional relationship found between the replikin peak genes of the tobacco mosaic virus and non-small cell lung cancer is one illustration of the relationship between replikin count, rapid replication and virulence. Possible implications of these findings of the same replikin structures an
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SOURCE Oncolab, Inc.
Copyright©2007 PR Newswire.
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