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ALPCO Announces the Launch of Rat and Mouse Proinsulin ELISA Kits
Date:1/26/2010

SALEM, N.H., Jan. 26 /PRNewswire/ -- ALPCO Diagnostics has developed two new low-sample volume ELISAs for the quantitative analysis of total proinsulin (I and II) in rats and mice.  These methods were developed using synthetic rat and mouse proinsulin I and II expressed in bacteria and purified from inclusion bodies, and were first introduced in an abstract presented at the Upper Midwest Islet Club Meeting in June 2009.

Both the Rat Proinsulin ELISA and Mouse Proinsulin ELISA allow for the direct quantification of total proinsulin (I & II) in serum.  Each kit requires only 10 microlitres of serum, giving researchers the opportunity to measure multiple analytes from a single sample collection.  The evaluation of a representative sample population of commonly used mouse and rat strains showed that > 90% of samples fell within the dynamic range of the respective ass
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