Navigation Links
AIDS researchers isolate new potent and broadly effective antibodies against HIV
Date:8/17/2011

NEW YORK, NY, LA JOLLA and SOUTH SAN FRANCISCO, CA, SEATTLE, WA, August 17, 2011 A team of researchers at and associated with the International AIDS Vaccine Initiative (IAVI), The Scripps Research Institute, the biotechnology company Theraclone Sciences and Monogram Biosciences Inc., a LabCorp company, report in the current issue of Nature the isolation of 17 novel antibodies capable of neutralizing a broad spectrum of variants of HIV, the virus that causes AIDS.

The new antibodies, large protein molecules that bind to pathogens and flag them for destruction, were isolated from blood serum samples collected in a continuing global search for broadly neutralizing antibodies (bNAbs) launched by IAVI. They should provide researchers with a new set of targets for the design of vaccine candidates that can elicit similar antibodies to protect people from contracting HIV. Some of the bNAbs blocked HIV infection of cells as much as 10 to 100 times as potently as previously discovered bNAbs.

"Most antiviral vaccines depend on stimulating the antibody response to work effectively," said Dennis Burton, a professor of immunology and microbial science and director of the IAVI Neutralizing Antibody Center at The Scripps Research Institute in La Jolla, Calif. Professor Burton, one of the senior authors of the study, is also a member of the Ragon Institute, in Cambridge, Mass. "Because of HIV's remarkable variability, an effective HIV vaccine will probably have to elicit broadly neutralizing antibodies. This is why we expect that these new antibodies will prove to be valuable assets to the field of AIDS vaccine research."

Only a minority of people who are HIV-positive begin to produce bNAbs after several years of infection. Animal studies suggest that such antibodies could block HIV infection if they were elicited by a preventive vaccine. Researchers prize bNAbs because their structural and biochemical analysis can reveal how to achieve a prevent
'/>"/>

Contact: Lauren Wesolowski
lwesolowski@iavi.org
212-328-7420
International AIDS Vaccine Initiative
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Pitt cancer researchers find key oncoprotein in Merkel cell carcinoma
2. Researchers create new experimental vaccine against chikungunya virus
3. USF researchers get $2.6 million NIH grant to investigate new post-stroke therapy
4. Childrens National collaborates with NIH researchers to identify gene variant in Proteus syndrome
5. Penn researchers describe key molecule that keeps immune cell development on track
6. Researchers find way to help donor adult blood stem cells overcome transplant rejection
7. UGA researchers use gold nanoparticles to diagnose flu in minutes
8. Researchers develop and test new molecule as a delivery vehicle to image and kill brain tumors
9. Stomach Cancer Tumors Have Genetic Differences: Researchers
10. Traumatic brain injury: NIH-funded researchers will assess biomarkers for diagnosis and treatment
11. Researchers map minority microbes in the colon
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/28/2015)... ... , ... The Kentucky State Department of Workforce Investment Commissioner Beth Kuhn recently ... for, they are unable to pass the initial drug test and therefore unable to ... order to be able to hire long-term, skilled talent. (1) Will Wesch, Director of ...
(Date:8/28/2015)... ... August 28, 2015 , ... For Dallas, the time is nearing for the ... USPI Tenet Health. , The American Heart Association hosts their well-known Heart Walk to ... that together, a difference can be made. Walkers can participate in the cause and ...
(Date:8/28/2015)... ... August 28, 2015 , ... The 6th Annual Survivor in the City, ... added yet another accolade to its cadre of widespread support—an official letter of support ... help of the medical community and the University of Illinois at Chicago’s Department of ...
(Date:8/28/2015)... ... August 28, 2015 , ... Saint Petersburg, FL ... with zero fat, carbs, sugar, gluten, lactose or caffeine in a convenient 2 ... 2015 SupplySide CPG Editor’s Choice Awards. , Five consumer packaged goods (CPG) products ...
(Date:8/28/2015)... (PRWEB) , ... August 28, 2015 , ... ... businesses nationwide. Addictions specialist, Dr. James Strawbridge, gives a new approach on solutions ... it should begin with the employer and employees getting together for meaningful group ...
Breaking Medicine News(10 mins):Health News:Hiring Obstacles: Drug Abuse a Problem for Workforce 2Health News:Hiring Obstacles: Drug Abuse a Problem for Workforce 3Health News:Hiring Obstacles: Drug Abuse a Problem for Workforce 4Health News:North Central Surgical Center’s Subsidiary Participates in Walk 2Health News:Chicago Mayor Pens Official Support of Annual Survivor in the City Event Benefitting Brain Aneurysm Foundation 2Health News:Chicago Mayor Pens Official Support of Annual Survivor in the City Event Benefitting Brain Aneurysm Foundation 3Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 2Health News:Pocket Protein™ Named 2015 CPG Editor’s Choice Award Finalist by Informa’s SupplySide 3
... could lead to new birth control for men , WEDNESDAY, ... of proteins called PLA2s play a vital role in sperm ... , The findings could improve understanding of male infertility and ... for infertility. , In one study, Japanese researchers found that ...
... ... share the leading position in the European Union’s “Novel Foods” category , ... Provo, UT (Vocus) April 28, 2010 -- ... Commission on Food Safety. Now, not only do noni juice and noni leaf have Novel ...
... ... that more than 100 baby boys die from circumcision complications each year, including from ... deaths are avoidable. , ... (PRWEB) April 28, 2010 -- The International Coalition for Genital Integrity (ICGI) acknowledges ...
... ... elegant celebration of the unique bond between adults and their moms - has been released publicly ... ... A Poem for Mothers - I Honor You " by bestselling author Brian Vaszily has been ...
... ... Brooklyn Bridge Park playground is closed for renovation less than a month after opening. ... New York (PRWEB) April 28, ... down this week. Less than a month after it opened, the much-anticipated playground was declared ...
... ... Develop a 100 Percent Lead Free Bubbler Retrofit Kit , ... Los Angeles, CA (Vocus) April 28, 2010 -- Acorn ... and a division of Acorn Engineering Company, announces a 100 percent lead-free bubbler retrofit kit ...
Cached Medicine News:Health News:Third European Novel Food Approval Received by Tahitian Noni International 2Health News:Children's Rights Group Agrees with New Study: Infant Circumcision Causes 100 Deaths Each Year in US 2Health News:Inspirational Short Video for Adults Who Celebrate Their Mothers Called "A Poem for Mothers" Released on YouTube 2Health News:Inspirational Short Video for Adults Who Celebrate Their Mothers Called "A Poem for Mothers" Released on YouTube 3Health News:New York Personal Injury Lawyer, David Perecman, says New Playground is No Place for Kids 2Health News:New York Personal Injury Lawyer, David Perecman, says New Playground is No Place for Kids 3Health News:The Acorn Aqua's Lead Free Bubbler 2
(Date:8/28/2015)... , Aug. 28, 2015 Perrigo Company plc ... the Mylan N.V. ("Mylan") (NASDAQ: MYL ) shareholder ... "Our views of Mylan,s offer to Perrigo ... based on our Board,s careful reflection of the value ... the limited choices that Mylan has allowed its shareholders ...
(Date:8/28/2015)... Korea , Aug. 28, 2015 ... University and Dr. Ra from Biostar , Published ... Confirmed 30% increase of lifespan through multiple IV administration ... physical vitality, and life expectancy found , Commercialization ... Korea have determined the possibility that adult mesenchymal stem ...
(Date:8/28/2015)... August 28, 2015 The global ... USD 49.12 billion by 2020, growing at a CAGR ... new report by Grand View Research, Inc. Monitoring services ... 49.7% from 2014 to 2020.      (Logo: ... along with rising incidences of chronic diseases such as ...
Breaking Medicine Technology:Perrigo Confident Its Shareholders Will Reject Mylan's Value Destructive Transaction 2Perrigo Confident Its Shareholders Will Reject Mylan's Value Destructive Transaction 3Perrigo Confident Its Shareholders Will Reject Mylan's Value Destructive Transaction 4Perrigo Confident Its Shareholders Will Reject Mylan's Value Destructive Transaction 5Korean Researchers Find the Possibility that Adult Mesenchymal Stem Cells (MSCs) May Extend Lifespan 2mHealth Market is Expected to Reach $49.12 Billion By 2020: Grand View Research, Inc. 2mHealth Market is Expected to Reach $49.12 Billion By 2020: Grand View Research, Inc. 3mHealth Market is Expected to Reach $49.12 Billion By 2020: Grand View Research, Inc. 4mHealth Market is Expected to Reach $49.12 Billion By 2020: Grand View Research, Inc. 5
... protection Properly manufactured radiation protective eyewear ... Our high quality frames and materials offer ... weight. Our lenses are made of Schott ... industry standards. Most Pulse Glasses are offered ...
Uvex Patriot Frame...
Panoramic styling that contours closely to the face and brow. Saddle bridge fits average to fuller noses. Adjustable temple hinge adjusts up or down, longer or shorter. Soft cushion behind ear for co...
QualCraft™ Euro Lite has a molded nylon frame that fits most faces. Universal keyhole nose bridge fits narrow to average noses. Available with or without lead vinyl-lined side shields....
Medicine Products: