Navigation Links
AIDS researchers isolate new potent and broadly effective antibodies against HIV
Date:8/17/2011

NEW YORK, NY, LA JOLLA and SOUTH SAN FRANCISCO, CA, SEATTLE, WA, August 17, 2011 A team of researchers at and associated with the International AIDS Vaccine Initiative (IAVI), The Scripps Research Institute, the biotechnology company Theraclone Sciences and Monogram Biosciences Inc., a LabCorp company, report in the current issue of Nature the isolation of 17 novel antibodies capable of neutralizing a broad spectrum of variants of HIV, the virus that causes AIDS.

The new antibodies, large protein molecules that bind to pathogens and flag them for destruction, were isolated from blood serum samples collected in a continuing global search for broadly neutralizing antibodies (bNAbs) launched by IAVI. They should provide researchers with a new set of targets for the design of vaccine candidates that can elicit similar antibodies to protect people from contracting HIV. Some of the bNAbs blocked HIV infection of cells as much as 10 to 100 times as potently as previously discovered bNAbs.

"Most antiviral vaccines depend on stimulating the antibody response to work effectively," said Dennis Burton, a professor of immunology and microbial science and director of the IAVI Neutralizing Antibody Center at The Scripps Research Institute in La Jolla, Calif. Professor Burton, one of the senior authors of the study, is also a member of the Ragon Institute, in Cambridge, Mass. "Because of HIV's remarkable variability, an effective HIV vaccine will probably have to elicit broadly neutralizing antibodies. This is why we expect that these new antibodies will prove to be valuable assets to the field of AIDS vaccine research."

Only a minority of people who are HIV-positive begin to produce bNAbs after several years of infection. Animal studies suggest that such antibodies could block HIV infection if they were elicited by a preventive vaccine. Researchers prize bNAbs because their structural and biochemical analysis can reveal how to achieve a prevent
'/>"/>

Contact: Lauren Wesolowski
lwesolowski@iavi.org
212-328-7420
International AIDS Vaccine Initiative
Source:Eurekalert

Page: 1 2 3 4

Related medicine news :

1. Pitt cancer researchers find key oncoprotein in Merkel cell carcinoma
2. Researchers create new experimental vaccine against chikungunya virus
3. USF researchers get $2.6 million NIH grant to investigate new post-stroke therapy
4. Childrens National collaborates with NIH researchers to identify gene variant in Proteus syndrome
5. Penn researchers describe key molecule that keeps immune cell development on track
6. Researchers find way to help donor adult blood stem cells overcome transplant rejection
7. UGA researchers use gold nanoparticles to diagnose flu in minutes
8. Researchers develop and test new molecule as a delivery vehicle to image and kill brain tumors
9. Stomach Cancer Tumors Have Genetic Differences: Researchers
10. Traumatic brain injury: NIH-funded researchers will assess biomarkers for diagnosis and treatment
11. Researchers map minority microbes in the colon
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/13/2014)... 13, 2014 Max International ... Mullin, will be the featured guest at its Charity ... Puerto Rico. Attendees will learn about Max’s health ... two exhibition basketball games and perform in a 3 ... of health- and energy-boosting supplements , has recently announced ...
(Date:7/13/2014)... Dallas, Texas (PRWEB) July 13, 2014 ... of aGVHD in the 6MM, from 8,062 diagnosed incident ... 2023, at an Annual Growth Rate (AGR) of 4.35%, ... have the highest number of diagnosed incident cases of ... whereas Spain will have the lowest number of diagnosed ...
(Date:7/13/2014)... According to the Kidney Disease Solution book review ... guide on what to do to eliminate the root ... in its review that readers can easily learn what foods ... kidney health. Vkool also informs in its Kidney Disease Solution ... kidney functions naturally. The book consists of a collection of ...
(Date:7/13/2014)... Celebrity fitness trainer and former World ... partnership with Aqua Health Labs for their flagship product ... . The collaboration was recently announced live on ESPN ... , actor, model, and a two time World Super ... he has prepared stars including Demi Moore, Hilary Swank ...
(Date:7/13/2014)... If Dr. Lawrence Power has his way, the ... http://www.HealthYourself101.com will expand people’s understanding of the causes, ... set out to provide a health education platform on this ... we say it? – entertaining to dig into and learn ... the remote learner – the solitary individual signing on from ...
Breaking Medicine News(10 mins):Health News:Max International Announces NBA Dream Team Member Chris Mullin as Featured Guest of Charity Event 2Health News:Max International Announces NBA Dream Team Member Chris Mullin as Featured Guest of Charity Event 3Health News:Max International Announces NBA Dream Team Member Chris Mullin as Featured Guest of Charity Event 4Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 2Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 3Health News:Graft-Versus-Host Disease Market (GVHD) Growing at 4.35% AGR to 2023 Says a New Report Available at ReportsnReports.com 4Health News:Kidney Disease Solution Book Review Exposes Duncan Capicchiano's Newly Updated Kidney Disease Treatment Plan – Vkool.com 2Health News:Kidney Disease Solution Book Review Exposes Duncan Capicchiano's Newly Updated Kidney Disease Treatment Plan – Vkool.com 3Health News:Celebrity Fitness Expert Supports Revolutionary New Health Supplement 2Health News:Retired Ann Arbor Physician and Professor Wields New Media to Teach Health Science 2Health News:Retired Ann Arbor Physician and Professor Wields New Media to Teach Health Science 3Health News:Retired Ann Arbor Physician and Professor Wields New Media to Teach Health Science 4
... (OTC Bulletin Board: PLCSF) announced today that it expects to ... fourth quarter and year ended December 31, 2008 before the ... to host a conference call to discuss those results at ... be joined via telephone by dialing (866) 356-3377 or (617) ...
... Living Life as Fully as Possible , ALEXANDRIA, Va., ... Organization wants all people to know that hospice delivers ... family caregivers who are coping with life-limiting illness. A ... Presents Legal Quandary," by Greg Bluestein, 03/02/09) carries a ...
... Known for Her Quest to Raise One Million Dollars for ... JACKSONVILLE, Fla., March 3 At 56, Linda Quirk has ... in just under a year. She began her trek ... 2008 and has since gone on to run the Great ...
... Inc. (Pink Sheets: SNDY) is pleased to announce that ... (FDA) Level II Baseline Inspection and received a NAI ... for the FDA to periodically perform unannounced inspections for ... FDA validates the Company,s quality system and its strict ...
... nine children, One in ten adults. , One in ... home , 402 people died due to asthma in 2006, ... People with asthma should have a written asthma action plan but ... telling patients what to do if their asthma gets worse. An ...
... disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are ... to cirrhosis and hepatocellular carcinoma. To date, ... in these conditions and no approved therapeutic ... system overexpression plays a central role in ...
Cached Medicine News:Health News:NHPCO Comments on Misleading Quote in Associated Press Article and Provides Helpful Information 2Health News:56-Year-Old Grandmother Heads to Antarctica to Run Her Seventh Worldwide Marathon in Under a Year 2Health News:56-Year-Old Grandmother Heads to Antarctica to Run Her Seventh Worldwide Marathon in Under a Year 3Health News:Solos Endoscopy, Inc. Successfully Completes FDA Inspection 2Health News:Is telmisartan effective in treating non-alcoholic steatohepatitis? 2Health News:Is telmisartan effective in treating non-alcoholic steatohepatitis? 3
(Date:7/10/2014)... U.S. Department of Health and Human Services (HHS) has ... Medical Center Seidman Cancer Center totaling $4.7 million to ... for patients with complex cancer. Titled ... model developed at UH to enhance care for adult ... need for high health care utilization.  ...
(Date:7/10/2014)... JORDAN, Utah , July 10, 2014  BC ... solutions, and MiE America , Inc., a leading ... have entered into a long-term agreement naming BC Technical ... the US. MiE and BC Technical ... strategic agreement to establish BC Technical as the service ...
(Date:7/10/2014)... R.I. , July 10, 2014 CVS Caremark ... board of directors has approved a quarterly dividend of $0.275 ... dividend is payable on August 1, 2014, to holders of ... CVS Caremark is dedicated to helping people ... pharmacy company in the United States . ...
Breaking Medicine Technology:University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 2University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 3University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 4BC Technical Partners With MiE America To Be Authorized Provider Of Systems & Service 2
The generously sized STERILE VIEW Monk Hood from DePuy provides splash protection in the chin and neck areas from body fluids and liquids. Shoulder cut outs and ties ensure a comfortable fit. This pr...
STERILE VIEW Knee High Boots are sealed thermoplastic boots that help provide splash protection from microorganisms, particulate mater and body fluids....
Digital Imaging for Optical Screening:,Diabetes, Glaucoma Macular Degeneration, and other retinal disease....
... Misys Laboratory is a ... that manages specimen data ... specimen tracking to final ... Laboratory is a multi-module ...
Medicine Products: