Navigation Links
AIDS Drug Slows Spread of Deadly Childhood Brain Cancer
Date:3/26/2009

Study finds it suppresses enzyme vital to tumor growth

THURSDAY, March 26 (HealthDay News) -- A drug approved to combat AIDS may also help slow the spread of a deadly type of brain tumor that tends to attack children.

A study published in the current issue of the International Journal of Cancer reports that ABC (Abacavir) suppresses the enzyme telomerase. Telomerase activity appears to be essential for certain tumor survival and growth, such as medulloblastoma -- a highly malignant cancer of the central nervous system.

In an international study, treatment with ABC improved the survival rate of medulloblastoma patients, although it did not cure them.

However, the medication appeared better tolerated by patients than other drugs used to target telomerase in trials, and ABC's safety record in long-term AIDS treatment would make it a good treatment option, lead researcher Francesca Pentimalli, an assistant adjunct professor at the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University in Philadelphia, said in a news release issued by the institute. The drug was also able to pass through the blood-brain barrier more easily than other tested compounds, so it could reach the medulloblastoma.

"Our report suggests further consideration and study of the use of ABC as an anti-telomerase agent in cancer," Pentimalli said.

More information

The U.S. National Cancer Institute has more about treatment trials for childhood medulloblastoma.



-- Kevin McKeever



SOURCE: Sbarro Health Research Organization, news release, March 24, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Chondroitin slows progression and relieves symptoms of knee osteoarthritis
2. Old gastrointestinal drug slows aging, McGill researchers say
3. Adult-onset diabetes slows mental functioning in several ways, with deficits appearing early
4. Vitamin K Slows Insulin Resistance in Older Men
5. New Drug Slows Thyroid Cancer
6. Anti-Mucus Drug Slows Symptoms of COPD
7. New Compound Slows HIV Replication
8. Treating safety research like other clinical studies slows progress
9. Historic Fundraising Initiative to Empower Women & Girls Worldwide Reaches $100 Million Quickly Even as U.S. Economy Slows
10. Green Tea, Mushroom Extract Combo Slows Sarcomas
11. Diabetes Drug Slows Clogging of Arteries
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
AIDS Drug Slows Spread of Deadly Childhood Brain Cancer
(Date:4/24/2017)... Boca Raton, Florida (PRWEB) , ... April 24, 2017 , ... ... natural chai teas, announced its products are now available for purchase on RevNutrition.com, a ... ancient form of tea first produced and popularized in ancient India and Siam. It ...
(Date:4/24/2017)... , ... April 24, 2017 , ... ... healthcare compliance and credentialing solutions, today announced that Kyle Allain has joined the ... Cactus Provider Management sales and operations, including provider, payor and managed care solutions. ...
(Date:4/24/2017)... ... April 24, 2017 , ... ... to be diagnosed globally; approximately 25,000 of them will be malignant.(1) As research ... of this type of healthcare model in the diagnosis and treatment of brain ...
(Date:4/24/2017)... IL (PRWEB) , ... April 24, 2017 , ... Rod ... the Senior Housing News website. , Rod has been at the forefront of Gardant ... company’s culture. As CEO, Rod has overseen the opening of more than 40 new ...
(Date:4/24/2017)... ... April 24, 2017 , ... As a former supermodel known for ... The good news for single women is that she put all the words in ... April 25th. Joan's insight, personal experiences and sparkling sense of humor have inspired her ...
Breaking Medicine News(10 mins):
(Date:4/20/2017)... April 20, 2017  Cogentix Medical, Inc. (NASDAQ: ... providing the Urology, Uro/Gyn and Gynecology markets with ... Keswani has joined the Company as Senior Vice ... created position, Mr. Keswani will report directly to ... "Our organization is delighted that Ash has ...
(Date:4/20/2017)... 20, 2017  RXi Pharmaceuticals Corporation (NASDAQ: RXII), ... address significant unmet medical needs, today announced that ... consumer product development program, based on its proprietary ... Investigative Dermatology (SID) 76 th Annual Meeting.  ... the sciences relevant to skin health and disease ...
(Date:4/20/2017)... -- AbbVie (NYSE: ABBV), a global biopharmaceutical company, today ... C virus (HCV) infected patients with genotype 1, ... (Child-Pugh A) achieved sustained virologic response at 12 ... pan-genotypic regimen of glecaprevir/pibrentasvir (G/P). These high SVR ... of G/P treatment without ribavirin. Patients with specific ...
Breaking Medicine Technology: