Navigation Links
AIDS Drug Slows Spread of Deadly Childhood Brain Cancer
Date:3/26/2009

Study finds it suppresses enzyme vital to tumor growth

THURSDAY, March 26 (HealthDay News) -- A drug approved to combat AIDS may also help slow the spread of a deadly type of brain tumor that tends to attack children.

A study published in the current issue of the International Journal of Cancer reports that ABC (Abacavir) suppresses the enzyme telomerase. Telomerase activity appears to be essential for certain tumor survival and growth, such as medulloblastoma -- a highly malignant cancer of the central nervous system.

In an international study, treatment with ABC improved the survival rate of medulloblastoma patients, although it did not cure them.

However, the medication appeared better tolerated by patients than other drugs used to target telomerase in trials, and ABC's safety record in long-term AIDS treatment would make it a good treatment option, lead researcher Francesca Pentimalli, an assistant adjunct professor at the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University in Philadelphia, said in a news release issued by the institute. The drug was also able to pass through the blood-brain barrier more easily than other tested compounds, so it could reach the medulloblastoma.

"Our report suggests further consideration and study of the use of ABC as an anti-telomerase agent in cancer," Pentimalli said.

More information

The U.S. National Cancer Institute has more about treatment trials for childhood medulloblastoma.



-- Kevin McKeever



SOURCE: Sbarro Health Research Organization, news release, March 24, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Chondroitin slows progression and relieves symptoms of knee osteoarthritis
2. Old gastrointestinal drug slows aging, McGill researchers say
3. Adult-onset diabetes slows mental functioning in several ways, with deficits appearing early
4. Vitamin K Slows Insulin Resistance in Older Men
5. New Drug Slows Thyroid Cancer
6. Anti-Mucus Drug Slows Symptoms of COPD
7. New Compound Slows HIV Replication
8. Treating safety research like other clinical studies slows progress
9. Historic Fundraising Initiative to Empower Women & Girls Worldwide Reaches $100 Million Quickly Even as U.S. Economy Slows
10. Green Tea, Mushroom Extract Combo Slows Sarcomas
11. Diabetes Drug Slows Clogging of Arteries
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
AIDS Drug Slows Spread of Deadly Childhood Brain Cancer
(Date:2/10/2016)... , ... February 10, 2016 , ... ... the ability of Medicare Advantage organizations to deliver medical services via telehealth, estimated ... “ATA has been advocating for such language for many years. Although there ...
(Date:2/10/2016)... ... February 10, 2016 , ... Early this week, Team Iconic at J. Walter ... KITKAT as the first global confectionery brand sourced from 100% sustainable cocoa. , The ... of their product, through activities that focus on better farming, better lives and better ...
(Date:2/10/2016)... , ... February 10, 2016 , ... ... together to expand dental health services to the developmentally disabled in the Coachella ... Dental’s operations to a new facility at 71-949 Highway 111, Suite 100-B, in ...
(Date:2/10/2016)... (PRWEB) , ... February 10, 2016 , ... ... and Video Remote Interpreting (VRI) within Healthcare, recently partnered with Heart City ... interpreting (VRI). , For nearly 23 years, Heart City Health Center has provided ...
(Date:2/10/2016)... ... 10, 2016 , ... The Wickman Agency in Garland, TX ... local community. Pledging to select a new beneficiary every 60 days, the agency ... goal is to bring community awareness to important local causes by forming campaigns ...
Breaking Medicine News(10 mins):
(Date:2/10/2016)... -- Vanda Pharmaceuticals Inc. (Vanda) (NASDAQ: VNDA ), ... quarter and full year ended December 31, 2015. ... a transformational year for Vanda with the continued growth ... approval of HETLIOZ for Non-24," said Mihael H. Polymeropoulos, ... to our U.S. product portfolio builds on this success ...
(Date:2/10/2016)... -- A new report from business intelligence provider GBI Research - ... disease market will more than double from just under $5 billion in 2014 ... (CAGR) of 11%. Canada , France ... Spain , the UK, and Japan , and will ... Canada , France , Germany ...
(Date:2/10/2016)... , Feb. 10, 2016  CVS Health (NYSE: ... living in Santa Clara County, CA ... on the Santa Clara University campus. CVS Pharmacy stores ... protect patients against the disease. Students at Santa Clara ... get vaccinated. In addition, anyone who has had close ...
Breaking Medicine Technology: