Navigation Links
AIDS Drug Slows Spread of Deadly Childhood Brain Cancer
Date:3/26/2009

Study finds it suppresses enzyme vital to tumor growth

THURSDAY, March 26 (HealthDay News) -- A drug approved to combat AIDS may also help slow the spread of a deadly type of brain tumor that tends to attack children.

A study published in the current issue of the International Journal of Cancer reports that ABC (Abacavir) suppresses the enzyme telomerase. Telomerase activity appears to be essential for certain tumor survival and growth, such as medulloblastoma -- a highly malignant cancer of the central nervous system.

In an international study, treatment with ABC improved the survival rate of medulloblastoma patients, although it did not cure them.

However, the medication appeared better tolerated by patients than other drugs used to target telomerase in trials, and ABC's safety record in long-term AIDS treatment would make it a good treatment option, lead researcher Francesca Pentimalli, an assistant adjunct professor at the Sbarro Institute for Cancer Research and Molecular Medicine at Temple University in Philadelphia, said in a news release issued by the institute. The drug was also able to pass through the blood-brain barrier more easily than other tested compounds, so it could reach the medulloblastoma.

"Our report suggests further consideration and study of the use of ABC as an anti-telomerase agent in cancer," Pentimalli said.

More information

The U.S. National Cancer Institute has more about treatment trials for childhood medulloblastoma.



-- Kevin McKeever



SOURCE: Sbarro Health Research Organization, news release, March 24, 2009


'/>"/>
Copyright©2009 ScoutNews,LLC.
All rights reserved  

Page: 1

Related medicine news :

1. Chondroitin slows progression and relieves symptoms of knee osteoarthritis
2. Old gastrointestinal drug slows aging, McGill researchers say
3. Adult-onset diabetes slows mental functioning in several ways, with deficits appearing early
4. Vitamin K Slows Insulin Resistance in Older Men
5. New Drug Slows Thyroid Cancer
6. Anti-Mucus Drug Slows Symptoms of COPD
7. New Compound Slows HIV Replication
8. Treating safety research like other clinical studies slows progress
9. Historic Fundraising Initiative to Empower Women & Girls Worldwide Reaches $100 Million Quickly Even as U.S. Economy Slows
10. Green Tea, Mushroom Extract Combo Slows Sarcomas
11. Diabetes Drug Slows Clogging of Arteries
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
AIDS Drug Slows Spread of Deadly Childhood Brain Cancer
(Date:9/19/2017)... ... September 19, 2017 , ... Public outrage over the toxins that exist ... deaf ears, leaving the water industry itself to research, develop and ultimately supply consumers ... curve in the field of natural alkaline water technologies, water filtration ...
(Date:9/19/2017)... ... September 19, 2017 , ... ... the launch of its magnesium-based orthopedic medical device, OsteoCrete®. OsteoCrete® bone void filler ... in the U.S. to incorporate magnesium, a critical property for bone health and ...
(Date:9/19/2017)... (PRWEB) , ... September 19, 2017 , ... Ron Norman, ... candidates today the importance of making a distinct rather than generic impression in the ... had to look through a stack of resumes knows that the first impression they ...
(Date:9/19/2017)... ... September 19, 2017 , ... ... to the Certified Emergency Nurse (CEN®) certification according to a large-scale ... value of certification study, conducted by the Human Resources Research Organization (HumRRO) in ...
(Date:9/18/2017)... , ... September 18, 2017 , ... A September 7 ... in Belfast indicating that aspirin, one of the world’s most common and least expensive ... Los Angeles area dentist Dr. Farzad Feiz of California Dental Group and Calabasas Dental ...
Breaking Medicine News(10 mins):
(Date:9/18/2017)... Sept. 18, 2017 EpiVax, Inc. ... bioinformatics and immune engineering, today announced a ... A (H7N9) vaccine. ... seasonal influenza and presents a challenge for ... exposure to be effective. Using state-of-the-art bioinformatics and ...
(Date:9/12/2017)... , Sept. 12, 2017  Consumer reviews on the independent ... as the number one company for hearing aids, ranking it ... fifteen other brands. ... Hearing Named #1 by Consumers For Hearing Aids ... Embrace Hearing is an online store that provides high performance, ...
(Date:9/9/2017)... Sept. 8, 2017 Dealmed Medical Supplies, ... of medical equipment, supplies, drugs, vaccines, and specialty medical ... into an agreement to acquire Vantage Medical Supplies, a ... Holtsville, New York . ... new and emerging medical practices, will operate under the ...
Breaking Medicine Technology: