Navigation Links
ADHD Drug Delays Puberty in Male Monkeys, Study Finds
Date:9/19/2011

By Maureen Salamon
HealthDay Reporter

MONDAY, Sept. 19 (HealthDay News) -- The widely used attention-deficit/hyperactivity disorder (ADHD) medication methylphenidate -- best known as Ritalin -- appears to be tied to delayed puberty in male monkeys.

But, researchers cautioned that the finding needs to be replicated before parents should concern themselves about similar effects in boys.

Male primates given methylphenidate over a 40-month span experienced "impaired testicular descent" and smaller-sized testicles, as well as lower testosterone levels, all of which resolved over the course of the study.

"To our knowledge, it's the first observation in primates to suggest an alteration in testicular function," said study author Dr. Donald Mattison, a medical officer at the National Institute of Child Health and Human Development, part of the U.S. National Institutes of Health.

"We believe they're interesting observations, but substantially more work needs to be done . . . to make sure they're repeatable," Mattison said. "It's really too early to say there are clinical implications."

The study is published in this week's online issue of the Proceedings of the National Academy of Sciences.

The most commonly diagnosed behavioral disorder in childhood, ADHD affects between 3 percent and 5 percent of school-age kids, mostly boys. Ritalin and other forms of methylphenidate have long been the most widely used drugs to treat ADHD, which involves issues of inattentiveness, overactivity and impulsivity. Other brand name versions of methylphenidate include Concerta, Metadate and Methylin.

According to Mattison, the young rhesus monkeys in the study were given either a low dose or high dose of methylphenidate, with the low dose designed to match typical blood levels of the drug observed in human ADHD patients. The high dose was intended to produce blood levels five to 10 times higher than used
'/>"/>

Copyright©2010 ScoutNews,LLC.
All rights reserved  

0

GOOD

Page: 1 2 3

Related medicine news :

1. One-Third of Severe Heart Attack Patients Have Treatment Delays
2. Many Pediatricians Arent Testing Tots for Developmental Delays
3. Hospital Delays Tied to Racial Divide in Heart Attack Care
4. Delays in Hospital Transfers for Heart Attack Patients May Raise Death Risk
5. Language Delays Seen in Kids in Institutions Beyond Age 2
6. Antifungal drug delays need for chemo in advanced prostate cancer
7. FDA Panel Delays Action on Dyes Used in Foods
8. Outcomes improved by longer delays between heart attacks and elective surgeries
9. Blood Pressure Drug Delays Kidney Disease in Diabetics
10. Heart Patients With Depression Often Find ER Delays
11. Delivery Even a Bit Early May Mean Developmental Delays
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
ADHD Drug Delays Puberty in Male Monkeys, Study Finds
(Date:5/23/2013)... Onlinefitnessreview.com recently published a comprehensive review of ... makes this diet work and how it compares to ... components of the program: eliminating foods that may slow ... personal motivation that is needed to succeed; and, learning ... the metabolism rate in top gear. , Nutritionist ...
(Date:5/23/2013)... May 23 (HealthDay News) -- People who eat at ... realize -- and teens are the worst offenders, a ... calories in their meals by as much as 34 ... 23 percent, and adults by as much as 20 ... a news release from the Robert Wood Johnson Foundation, ...
(Date:5/23/2013)... May 23, 2013 Susquehanna Health ... offering a comprehensive babysitting training course for adolescents age ... developed by Indianapolis pediatrician Dr. Patricia Keener after a ... of an adult sitter who didn’t know how to ... development program with a medical basis that aims to ...
(Date:5/23/2013)... "triple negative" carries a poor prognosis, with limited treatment ... cancer cells the way it,s supposed to. New research ... respond to chemotherapy, and identifies a mechanism to rectify ... Li, PhD, and his team at Western,s Schulich School ... Numb functions to promote the death of cancer cells ...
(Date:5/23/2013)... DC (PRWEB) May 23, 2013 The ... a great deal of control over their level of ... weight, yet far fewer are actually taking that control. ... Food Information Council (IFIC) Foundation’s 2013 Food & Health ... respondents say it’s possible to have “a great deal ...
Breaking Medicine News(10 mins):Health News:Onlinefitnessreview.com Publishes 7 Day Belly Blast Diet Review 2Health News:How Many Calories in Your Fast-Food Meal? Guess Again 2Health News:Susquehanna Health Offers Safe Sitter Course for Tweens and Teens 2Health News:Susquehanna Health Offers Safe Sitter Course for Tweens and Teens 3Health News:Americans Experience “Control Gap” Regarding Their Weight, Diet, Activity Level; Rate Their Overall Diet a “B-Minus” 2Health News:Americans Experience “Control Gap” Regarding Their Weight, Diet, Activity Level; Rate Their Overall Diet a “B-Minus” 3Health News:Americans Experience “Control Gap” Regarding Their Weight, Diet, Activity Level; Rate Their Overall Diet a “B-Minus” 4
... beauticians may be affected by phthalates in these products, ... Mothers exposed to a common hairspray chemical while at ... with an abnormally placed urinary opening, a new report ... and nail and hair products contain chemicals called phthalates, ...
... BELLEVUE, Wash., Nov. 26 Edifecs, Inc., ... announced today that CNSI has,selected the Edifecs ... implementation of a new Medicaid Management Information ... Social Services (DSS). The Edifecs Healthcare,Accelerator ...
... research team led by Mitchell Lazar, MD, PhD, ... Metabolism at the University of Pennsylvania School of ... coordinates body rhythms and metabolism. , Lazar ... Penn Veterinary Medicine doctoral student Theresa Alenghat, studied ...
... Micromet, Inc. (Nasdaq: MITI ), a ... of cancer, inflammation and autoimmune diseases, today announced that ... will present at the Piper Jaffray 20th Annual Health ... Wednesday, December 3, 2008. A simultaneous webcast of ...
... help regulate appetite , , WEDNESDAY, Nov. 26 (HealthDay News) -- ... this year, a molecule produced in the small intestine will ... brain the impact of the fat you,ve just consumed. , ... a while. But, researchers are hoping that one day variations ...
... across the world are to share skills and experiences ... Africa, organised by the Wellcome Trust. , The conference ... will take place from 2-5 December at the Africa ... bring together practitioners working in the fields of public ...
Cached Medicine News:Health News:CNSI Selects Edifecs Healthcare Accelerator Suite(TM) for MMIS Solution to Support South Dakota Medicaid Program 2Health News:Molecular partnership controls daily rhythms, body metabolism 2Health News:Micromet to Present at the Piper Jaffray 20th Annual Health Care Conference 2Health News:Micromet to Present at the Piper Jaffray 20th Annual Health Care Conference 3Health News:Micromet to Present at the Piper Jaffray 20th Annual Health Care Conference 4Health News:Fat-Sensing Hormones Might Fight Obesity 2Health News:International workshop aims to boost public engagement work in developing countries 2Health News:International workshop aims to boost public engagement work in developing countries 3
(Date:5/23/2013)... Neurocrine Biosciences, Inc. (Nasdaq: NBIX ) announced today ... Executive Officer of Neurocrine Biosciences, will be presenting at the ... in Boston.   The live presentation takes place ... 8:20 a.m. Pacific Time.  The presentation will be webcast and ... . If you are unable to attend ...
(Date:5/23/2013)... Hearing health affects a man,s lifestyle, and if ... and professionally engaged, he should address any hearing loss he ... Better Hearing Institute (BHI) is delivering to men ... Week , which leads up to and includes Father,s Day. ... through June 16. To help men address ...
(Date:5/23/2013)... 2013  Hadasit Bio-Holdings Ltd. (TASE: HDST, OTC: ... based on intellectual property developed and owned by ... foremost medical research center, today announced that its ... funding from the Israeli Ministry of Industry and ... support product development and advance clinical trials. Cell ...
Breaking Medicine Technology:Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 2Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 3Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 4Hadasit Bio-Holdings Ltd. Portfolio Company - Cell Cure Neurosciences Ltd. Received Additional Government Support 2
... Mich., Aug. 6 Terumo Heart, Inc. announced,that ... Ventricular Assist,System (LVAS) took place on July 30 ... Arbor, Michigan. The surgery was performed by,Francis Pagani, ... Pivotal Trial. DuraHeart is the world,s first third,generation ...
... Nexgen Spine, a leading,developer of innovative spinal implants ... today that it has received CE mark,approval to ... European,Union., "We are delighted that the Physio-L(R) ... Alastair Clemow, Ph.D., President and CEO,of Nexgen Spine. ...
Cached Medicine Technology:First DuraHeart(TM) Left Ventricular Assist System Implanted in the U.S. Pivotal Trial 2Nexgen Spine Receives CE Mark Approval for the Physio-L(R) Artificial Disc 2
... active hormone synthesized within the follicular cells ... synthesized via a series of steps involving: ... (ii) iodination of tyrosine residues in the ... and 3,5-diiodotyrosine (MIT and DIT), and (iii) ...
... factor binding protein-3 (IGFBP-3) is the main binding ... as a component of the ~150 kDa ternary ... of IGF-I or IGF-II and ALS, allowing IGFBP-3, ... the IGFs. The molar concentration of IGFBP-3 in ...
... a monomeric protein produced and stored in ... is released from the pituitary into the ... regulatory control of hypothalamic somatostatin (SS) and ... frequency of GH release appears to be ...
... somatomedin C) is a 7.6 kDa peptide produced ... potent mitogen of cellular proliferation, exerting its actions ... circulation, IGF-I is bound to IGF-binding proteins (IGFBPs), ... by modulating the interaction of IGF-I with the ...
Medicine Products: