Navigation Links
ACE Inhibitor as Effective as More Expensive Blood Pressure Drug
Date:3/31/2008

Study focused on more than 17,000 people with coronary artery disease or diabetes

MONDAY, March 31 (HealthDay News) -- Treatment with an ACE inhibitor drug was as effective in reducing deaths, heart attacks and stroke in a high-risk group of patients as a newer and more expensive angiotensin-receptor blocker (ARB) drug, a large international study has found.

The study of more than 17,000 people with coronary artery disease or diabetes found no major differences between those treated with the widely used ACE inhibitor ramipril (Altace) and those given the ARB telmisartan (Micardis).

"This is the first study in such a population that shows ACE inhibitors are as effective as ARBs," said study leader Dr. Salim Yusuf, a professor of medicine at McMaster University, in Hamilton, Ontario, Canada.

The finding might reduce the use of ARBs for such high-risk people, he said. "Even before the trial, many physicians have used ACE inhibitors as a first choice," Yusuf said. "I believe it will have an impact on practice."

The findings were to be presented Monday at the American College of Cardiology annual meeting in Chicago, and will be published in the April 10 issue of the New England Journal of Medicine.

Both classes of drugs are prescribed to lower blood pressure. But they act in different ways to block the activity of angiotensin, a molecule that narrows blood vessels.

"The main value of ARBs as monotherapy in patients with cardiovascular disease is, in my opinion, as a substitute for an ACE inhibitor in a patient who cannot tolerate the ACE inhibitor because of cough," said Dr. John J.V. McMurray, a professor of medical cardiology at the University of Glasgow in Scotland, who wrote an editorial accompanying the journal report.

"ACE inhibitors have never been tested in an outcome study in this patient population, and an ACE inhibitor and ARB have never been compared in this pat
'/>"/>

Copyright©2008 ScoutNews,LLC.
All rights reserved  

Page: 1 2

Related medicine news :

1. NSAIDs: Painkillers, inflammation inhibitors, anti-cancer drugs and new de-methylating agents
2. Late Use of Aromatase Inhibitor Still Effective Against Breast Cancer
3. Effect of tumor necrosis factor a inhibitors on heart failure risk in RA Patients
4. Amira Pharmaceuticals and GlaxoSmithKline Enter Global Agreement for FLAP Inhibitor Program
5. S*BIOs Oral JAK2 Inhibitor SB1518 Demonstrates Therapeutic Potential for the Treatment of Myeloproliferative and Other Hematological Disorders
6. Silencing small but mighty cancer inhibitors
7. SGX Pharmaceuticals Submits Investigational New Drug Application for SGX523, a Highly Potent, Selective, Orally Bioavailable cMET Inhibitor
8. S*BIO Expands Pipeline With the Development of a Unique Flt3 -CDK Inhibitor as a Targeted Therapy for Acute Leukemias
9. Data Show SuperGens Multi-Targeted Tyrosine Kinase Inhibitor Demonstrates Pre-clinical Activity in Glioblastoma Multiforme
10. Impending FDA Approval Decision on the First HIV Integrase Inhibitor Can Have Significant Impact for Patients
11. Guardian Survey: Despite Perceived Effectiveness, Most Employees Who Participate in Wellness Programs Do Not Stay Committed
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
ACE Inhibitor as Effective as More Expensive Blood Pressure Drug
(Date:9/17/2014)... 17, 2014 In a continuing effort ... Nile virus threats, Mosquito Shield of the South Shore ... with the Hanover Youth Athletic Association to treat area ... daily practices going until dusk, prime mosquito feeding time, ... athletes, coaches, and parents involved in outdoor athletic activities. ...
(Date:9/17/2014)... 2014 Stand Up for Heroes, New ... to the Theater at Madison Square Garden, Wednesday, Nov. ... Foundation (BWF) and New York Comedy Festival (NYCF), the ... veterans and their families. , The charitable event ... Oliver, Bruce Springsteen, Brian Williams and other surprise guests. ...
(Date:9/17/2014)... (PRWEB) September 17, 2014 Health ... increase efficiency. Today, Pharmacy Healthcare Solutions, a wholly ... web-based analysis and forecasting tool that enables hospitals ... the impact of medications on improved patient outcomes. ... uses pharmacy purchase data to identify areas of ...
(Date:9/17/2014)... 16, 2014) A study led by St. Jude ... dose threshold below which male childhood cancer survivors ... study appears in September 17 edition of the ... which patients are at highest risk for reduced ... to eventually increase use of pre-treatment fertility preservation ...
(Date:9/17/2014)... (PRWEB) September 17, 2014 MarijuanaStock.net, ... http://www.marijuanastock.net , recently launched a “Video” section that ... cannabis companies in the marijuana industry made available ... a website visitor is given access to numerous ... to marijuana-related businesses and the issues they face. ...
Breaking Medicine News(10 mins):Health News:Mosquito Shield of South Shore Again Partners with Hanover Youth Athletic Association 2Health News:Louis C.K., John Mulaney, John Oliver, Bruce Springsteen, Brian Williams & More to Perform at 8th Annual Stand Up for Heroes at Theater at Madison Square Garden, Nov. 5 2Health News:Louis C.K., John Mulaney, John Oliver, Bruce Springsteen, Brian Williams & More to Perform at 8th Annual Stand Up for Heroes at Theater at Madison Square Garden, Nov. 5 3Health News:Louis C.K., John Mulaney, John Oliver, Bruce Springsteen, Brian Williams & More to Perform at 8th Annual Stand Up for Heroes at Theater at Madison Square Garden, Nov. 5 4Health News:Louis C.K., John Mulaney, John Oliver, Bruce Springsteen, Brian Williams & More to Perform at 8th Annual Stand Up for Heroes at Theater at Madison Square Garden, Nov. 5 5Health News:Pharmacy Healthcare Solutions Launches TARxGET™ Reporting 2Health News:Pharmacy Healthcare Solutions Launches TARxGET™ Reporting 3Health News:Improved risk identification will aid fertility preservation in young male cancer patients 2Health News:Improved risk identification will aid fertility preservation in young male cancer patients 3Health News:MarijuanaStock.net Adds Business News Video Section to Their Website 2
... drilling, new energy technologies, science at the LHC, tests of gravity ... edge science will be featured in talks at this year,s April ... April 30 to May 3 at the Hyatt Hotel Orange County ... free of charge. Registration information can be found at the end ...
... be at increased risk of damage to the same brain ... by researchers at Washington University School of Medicine in St. ... that scientists have linked to neurological problems including Parkinson,s disease-like ... than 1 million workers who perform welding as a part ...
... the School of Public Health at the University of ... of depression may have long-term benefits. The data ... a longitudinal Canadian study, and showed depressed adults who ... depressed eight years later, compared to depressed adults who ...
... , WEDNESDAY, April 6 (HealthDay News) -- Long-term users ... damage, warns a new study. Brain scans showed an ... and a lower proportion of overall gray matter among long-term ... that people who use ecstasy can develop serious memory problems, ...
... THURSDAY, April 7 (HealthDay News) -- For American parents, doctors ... of children,s vaccines, a new study indicates. Researchers conducted ... and younger, and found that 76 percent said they trusted ... information about vaccine safety. Other sources trusted "a lot" ...
... (HealthDay News) -- A new report reveals that 98.8 percent ... to 64 with untreated alcohol abuse disorders don,t believe they ... nearly 6 million American adults with untreated alcohol dependence recognize ... to increase public awareness about adult problem drinking, how to ...
Cached Medicine News:Health News:Nuclear security, deep water drilling, black hole signal flares and more at 2011 APS annual meeting 2Health News:Nuclear security, deep water drilling, black hole signal flares and more at 2011 APS annual meeting 3Health News:Nuclear security, deep water drilling, black hole signal flares and more at 2011 APS annual meeting 4Health News:Nuclear security, deep water drilling, black hole signal flares and more at 2011 APS annual meeting 5Health News:Nuclear security, deep water drilling, black hole signal flares and more at 2011 APS annual meeting 6Health News:Nuclear security, deep water drilling, black hole signal flares and more at 2011 APS annual meeting 7Health News:Nuclear security, deep water drilling, black hole signal flares and more at 2011 APS annual meeting 8Health News:Welders may be at increased risk for brain damage 2Health News:Treatment for depression a long-term solution 2Health News:Long-Term Ecstasy Users at Risk for Brain Damage, Study Warns 2Health News:Doctors Most Trusted Source of Vaccine Information, Study Finds 2Health News:Only 1.2% of Alcohol Abusers Know They Need Help: Report 2
(Date:9/17/2014)... 17 2014 IBM (NYSE: IBM ) ... IBM technical computing and storage technology to accelerate ... These services deliver critically important information to help ... unique cancer, which could lead to better health ... in general. Today, optimal cancer care ...
(Date:9/17/2014)... , Switzerland , September 17, ... Debiopharm Group ™ , is proud to congratulate Biocartis ... instrument. Debiopharm Diagnostics is a long-time investor in ... Idylla ™ Biocartis, fully automated, real-time ... offer physicians fast and easy access to clinical ...
(Date:9/16/2014)... Sept. 16, 2014  ROX Medical today presented ... multi-center, prospective, randomized, controlled, blinded endpoint study of ... hypertension. The CONTROL-HTN trial, NCT01642498, evaluated the safety and ... connection between a central artery and vein in ... hypertension. The primary outcomes are reduction of blood ...
Breaking Medicine Technology:Caris Life Sciences Selects IBM to Accelerate Use of Molecular Profiling in Cancer Treatment Selection 2Caris Life Sciences Selects IBM to Accelerate Use of Molecular Profiling in Cancer Treatment Selection 3Caris Life Sciences Selects IBM to Accelerate Use of Molecular Profiling in Cancer Treatment Selection 4Debiopharm Diagnostics Portfolio Company Biocartis Ships its First Idylla Instrument 2ROX Medical presents positive data for CONTROL-HTN resistant hypertension trial 2
... Health Solutions, Inc. (NYSE: MHS ) will webcast its Annual Meeting ...  The presentations by David B. Snow Jr. , chairman and CEO, and ... , , ... Investor Relations section at www.medco.com/investor . The webcast will be available for ...
... May, AllerAir is supporting Multiple Chemical Sensitivities and Chemical Injury ...   , , , ... chemical awareness tips and a $50.00 gift certificate available via ... articles will be dedicated to Multiple Chemical Sensitivities ...
Cached Medicine Technology:Medco Announces Webcast for Annual Meeting of Shareholders 2Multiple Chemical Sensitivities Are Real 2Multiple Chemical Sensitivities Are Real 3
... Bird and Cronin, Inc. ... of Patient Footwear, Orthopedic ... Care Products. Our products ... quality and available in ...
... Aspen® CTO combines highly effective immobilization of ... a level of comfort that makes it ... substantially progressive immobilization in going from a ... and then on to a four-post orthosis. ...
... Shoulder Immobilizer with Contoured ... Navy cotton sling with foam-padded ... body straps. Quick-release closure buckles. ... 35 covered abduction wedge to ...
The Humeral Stabilizing System is a terrific option for immobilization of stable humeral fractures, stablesupracondular fractures, and biceps/triceps repairs....
Medicine Products: