Navigation Links
A turn-off for cancer
Date:6/7/2010

Although plants and animals are very different organisms, they share a surprising number of biological mechanisms. A plant biologist at Tel Aviv University says that one of these mechanisms may be the answer for turning off cancer growth in humans.

Prof. Shaul Yalovsky, of the Molecular Biology and Ecology of Plants Department at Tel Aviv University, has identified a "switch" that can turn on cell growth in plants. Now, in a laboratory setting, he can apply the mechanism to reshape cells, grow new tissues, and respond to bacterial or viral invaders.

The switch is actually a fat molecule that modulates a group of proteins called ROPs. Reported in the scientific journal Current Biology, Prof. Yalovsky's research group, in collaboration with Prof. Yoav Henis and Dr. Joel Hirsch of TAU's Departments of Neurobiology and Biochemistry, has determined that this fat molecule is required for ROP activity. Proteins very similar to ROPs exist in humans and provide chemical signals that tell cancer when to metastasize. Now that they know how to regulate ROPs in plants, the researchers believe they are one step away from turning this ROP-like switch off in humans a process which could prevent tumor growth.

An ancient secret revealed

"We've stumbled upon an ancient mechanism that regulates the function of these proteins, proteins which are found in both plants and humans," says Prof. Yalovsky, explaining that this mechanism already regulates the immune response to pathogen invaders in the human body. ROP-like proteins are also involved in wound healing and development of nerve cells in the brain.

"When these proteins are turned 'on,' they can initiate processes like cell division and growth," says Prof. Yalovsky. "Through our genetic engineering, these proteins could be manipulated in humans to speed up tissue healing, or turned off to slow or stop the growth of tumors."

ROPs bind to a small molecul
'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert  

Page: 1 2

Related medicine news :

1. Non-melanoma skin cancer may help identify survivors at increased risk for future cancers
2. Consortium seeks best treatment for HIV-positive cancer patients
3. Drug that helps metastatic colon cancer of no benefit in less advanced tumors
4. B2Discovery: Entrepreneurs and researchers join forces to conquer cancer
5. ASCO data show serum DNA blood tests detect cancers with high sensitivity and specificity
6. Molecular imaging detects recurrent prostate cancer
7. New treatment regimen shown effective against advanced ovarian cancer
8. Targeted Therapy Shows Promise Against Deadly Brain Cancer
9. Less-invasive Lymph Node Resection Following Breast Cancer Surgery Confirmed as Standard of Care in Eight-year Study Led by AGH Doctors
10. Researchers Report Treatment Headway Against Lung Cancer
11. Selenium shows no benefit in prevention of lung cancer
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A turn-off for cancer
(Date:9/2/2015)... ... September 02, 2015 , ... Telehealth represents a growing trend among ... handle the telehealth services of more than 12 Blues plan clients. The September ... takes a look this growing trend, interviewing executives at Capital Blue Cross, whose telehealth ...
(Date:9/2/2015)... ... September 02, 2015 , ... In “Failure Lab: Weight Loss Surgery was ... August 25th, writer Akela Stanfield detailed her lifelong struggle with obesity that eventually led ... had always seen herself as someone who would lose weight through sheer self-control, the ...
(Date:9/2/2015)... ... September 02, 2015 , ... Splashtop Inc., the ... to its screen mirroring and extending product line -- Splashtop Wired XDisplay ... in local WIFI setting, the new Splashtop Wired XDisplay delivers enhanced performance and ...
(Date:9/2/2015)... ... September 02, 2015 , ... Good health and a good ... Shield of New Jersey (Horizon BCBSNJ) donated $11,000 to the New Jersey Golf Foundation ... foundation at the start of The Barclays, Horizon BCBSNJ challenged PGA TOUR golfer and ...
(Date:9/2/2015)... , ... September 02, 2015 , ... ... combining both naturopathic and allopathic medicine, opens its second location this week at ... features roughly 1000 square feet of lounge space for patients to relax while ...
Breaking Medicine News(10 mins):Health News:AIS Newsletter Focuses on Growing Telehealth Trend Among Blues Plans 2Health News:AIS Newsletter Focuses on Growing Telehealth Trend Among Blues Plans 3Health News:Recent Editorial on Bariatric Surgery Acceptance Illuminates a Typical Journey Towards Weight Loss Surgery, Notes Dr. Michael Feiz 2Health News:Splashtop Launches Wired XDisplay, the Fastest Screen Sharing Solution for Extending and Mirroring Your Computer Screen to Mobile Devices 2Health News:Splashtop Launches Wired XDisplay, the Fastest Screen Sharing Solution for Extending and Mirroring Your Computer Screen to Mobile Devices 3Health News:Horizon BCBSNJ’s Healthy Steps Challenge Raises an Additional $6,000 for the NJ Golf Foundation with Help from PGA TOUR Golfer Morgan Hoffmann 2Health News:Horizon BCBSNJ’s Healthy Steps Challenge Raises an Additional $6,000 for the NJ Golf Foundation with Help from PGA TOUR Golfer Morgan Hoffmann 3Health News:The Hydration Room Opens New Location In Laguna Beach, California 2Health News:The Hydration Room Opens New Location In Laguna Beach, California 3Health News:The Hydration Room Opens New Location In Laguna Beach, California 4
... ABT ),will present at the Citi Investment Research ... C. Freyman, executive vice president,finance and chief financial officer, ... Central time., A live audio webcast of the ... at http://www.abbottinvestor.com . An,archived edition of the presentation ...
... With the economy tight and,sales forces shrinking across ... maintain an effective sales force. Regardless, a company,s ... success going forward. That,success is predicated on establishing ... goals and managing groups in a way,that meets ...
... increase the risk of Alzheimers Disease by as much as ... issue of Obesity Reviews. , But its not just weight ... have an elevated risk of dementia, unlike people who are ... detailed review of 10 international studies published since 1995, covering ...
... staffing company to launch nationally-syndicated television ... ... Access,Nurses announced today a national campaign to change the image of nursing,in ... lives of nurses working on the front lines of modern,healthcare. The show, ...
... May 7 Emageon Inc. (Nasdaq:,EMAG), a leader in ... imaging facilities, will hold its,quarterly conference call to discuss ... at 10:00 AM Eastern Time. The company anticipates,that these ... the NASDAQ,stock market opens on May 12, 2008., ...
... May 7 AMDL, Inc. (Amex: ... in Shenzhen, Jiangxi,and Jilin, China, is a ... its subsidiary Jade Pharmaceutical Inc. (JPI),the Company ... of diagnostic, pharmaceutical, nutritional supplement, and,cosmetic products., ...
Cached Medicine News:Health News:Best Practice Database: Complimentary Excerpt of Three Sales Force Excellence Studies 2Health News:Obesity can increase dementia risk by up to 80 percent 2Health News:Nursing Shortage Spurs Campaign to Change the Image of Nursing in the Media 2Health News:Emageon Inc. to Host First Quarter 2008 Financial Results Conference Call May 12, 2008 2Health News:AMDL Signs Letter of Intent to Purchase a China Based Pharmaceutical Distribution Company 2Health News:AMDL Signs Letter of Intent to Purchase a China Based Pharmaceutical Distribution Company 3
(Date:9/2/2015)... Sept. 2, 2015 About Duchenne muscular ... disease, which generally affects the male population. It ... The disease is caused due to mutations in ... of production of dystrophin (a protein essential for ... of dystrophin weakens muscle function, causes loss of ...
(Date:9/2/2015)...  Array BioPharma Inc. (Nasdaq: ARRY ) ... Ron Squarer , will present at the Wells ... is welcome to participate in the conference through ... Fargo Securities Healthcare ConferencePresenter: Ron Squarer, Chief Executive ... a.m. Eastern Time Webcast: www.arraybiopharma.com   ...
(Date:9/2/2015)... YORK , Sept. 2, 2015 About ... is a malignant condition characterized by increased production of ... affects B-lymphocytes and then it can spread to other ... at later stages because of the slow buildup of ... the malignancy spreads to the spleen, liver, and lymph ...
Breaking Medicine Technology:Global Duchenne Muscular Dystrophy Drugs Market 2015-2019 2Global Duchenne Muscular Dystrophy Drugs Market 2015-2019 3Global Chronic Lymphocytic Leukemia Therapeutics Market 2015-2019 2Global Chronic Lymphocytic Leukemia Therapeutics Market 2015-2019 3
... Xlumena, Inc., a privately-held provider of innovative technology ... that it has received CE Mark approval for its ... system that enables exchange-free access, tract dilation and delivery ... NAVIX will join the AXIOS Stent and Delivery System ...
... The Chinese Biopharmaceutical Association-USA (CBA) successfully held its 16 ... US.   With the theme of ... the conference drew nearly 500 attendees with ... exhibited at the conference, including Chinese leading biotech parks, ...
Cached Medicine Technology:Xlumena Receives CE Mark for NAVIX™, Second Product to Enter European Market 2Chinese Biopharmaceutical Association Successfully Holds 16th Annual Conference 2Chinese Biopharmaceutical Association Successfully Holds 16th Annual Conference 3
... ARUP Laboratories is a national reference laboratory ... research and development. ARUP offers an extensive ... medical tests in clinical and anatomic pathology. ... Laboratories' clients include more than half of ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: