Navigation Links
A therapy for baby boomers to sleep on
Date:8/15/2008

If you're over 55 and have spent more than a few sleepless nights, you're not alone -- insomnia affects about half of all people over 55 -- but you may also be at increased risk for physical and mental ailments.

Many older adults don't get enough restorative sleep, leading to serious health concerns, including cardiovascular disease, obesity, diabetes, memory problems and increased rates of depression. Unfortunately, current sleeping pills are associated with memory problems, a risk for falls, dependency, withdrawal symptoms and disturbed sleeping patterns.

Circadin, a new drug developed at Tel Aviv University by Prof. Nava Zisapel, a chemist and neurobiologist from TAU's George S. Wise Faculty of Life Sciences, may help America's aging baby boomers get the much-needed sleep they need. Recent results from Prof. Zisapel's research with Circadin appear in the Journal of Sleep Research and are reviewed in Aging Health.

How the Body Tells Time

Prof. Zisapel's research centers on the hormone melatonin, which affects the way our biological functions differentiate between day and night. "As we age, the melatonin hormone signal weakens," says Prof. Zisapel. "As a result, our bodies and brains feel less difference between day and night."

Exacerbating the effect of low melatonin levels, aging people tend to sleep in a less organized fashion than younger people, Prof. Zisapel explains. "People are sleeping in front of the TV, or nodding off during conversations, and taking long afternoon naps. This leads to less sleep at night. In a way, their sleep habits become more like babies', and less like those of healthy adults who sleep in consolidated periods during the night."

Mimicking the profile of nighttime melatonin found in our bodies, Circadin replenishes the much-needed hormone, which declines steadily with age. Clinical trials in the United States and Europe found that Circadin improves sleep quality and morning alertness, and helps those 55 and over get a better night's sleep.

Her new drug therapy "improves sleep and daytime vigilance, helping to re-organize the circadian system, the body's internal clock," Prof. Zisapel says. Added benefits include more normalized blood pressure and blood sugar levels at night. The formulation also has a profound effect on the blind, whose biological clock is disturbed because they can't see light, a trigger for synchronizing with the external day/night cycle.

Advice for Sound Sleep Hygiene

Until Circadin is available in the United States, there are some simple steps seniors can take to get a good night's sleep, Prof. Zisapel says. Spending a couple of hours outdoors every day can help. Sipping lattes on a cafe patio (away from direct sunlight) can be pleasurable, and increases the exposure to natural light from the blue-green spectrum. Experiencing a full spectrum of light during the day could also be beneficial, as is routine exercise and avoiding daytime naps and sleeping in front of the TV.


'/>"/>

Contact: George Hunka
ghunka@aftau.org
212-742-9070
American Friends of Tel Aviv University
Source:Eurekalert  

Related medicine news :

1. Vision restoration therapy shown to improve brain activity in brain injured patients
2. HIV therapy in pregnancy-data support WHO recommendations
3. Family-based treatment more effective than supportive psychotherapy in treating bulimia
4. Trial to Test Gene Therapy for Angina in Women
5. One of the Largest Post-WHI Physician Surveys Shows More Education is Needed: Patient Misinformation About Hormone Therapy Remains High
6. Aromatherapy Gift Line Sheds Humorous Light on Modern Therapy
7. Chemotherapy may be culprit for fatigue in breast cancer survivors
8. Atlanta Falcons Physical Therapy Centers Set to Launch This Fall
9. New Drug No Substitute for Standard Blood-Clot Therapy
10. Stem Cell Therapy Disappoints Against Rare Kidney Ailment
11. Nucletron Announces Management Buy-Out to More Effectively Meet the Demands of Its Customers and the Radiation Therapy Community
Post Your Comments:
*Name:
*Comment:
*Email:
Related Image:
A therapy for baby boomers to sleep on
(Date:2/5/2016)... ... 05, 2016 , ... US Sports Camps , official operators of Nike ... high-performance kids yoga training. ChildLight Yoga Studio is centrally situated in the picturesque New ... ChildLight Yoga Studio founder Lisa Flynn expresses her excitement, “We are thrilled to be ...
(Date:2/5/2016)... ... , ... Give To Cure today announced that it is working ... To Cure’s campaign that is crowdfunding clinical trials to help find cures faster for ... a smart device. In 2015 alone, Venmo processed $7.5 billion in transactions among users. ...
(Date:2/5/2016)... ... ... Dr. Justin Scott and Dr. Lydia Muccioli of Pure Dental Health ... in need. The event is scheduled to take place on February 27, 2016 from ... dental care to community members in need. Each patient will be given the opportunity ...
(Date:2/5/2016)... ... February 05, 2016 , ... In sleep, when the defenses of ... A hallmark feature of patients with eating disorders is significant self-criticism, and consequently these ... and obsessions are regarded as maladaptive means for coping with this unease, but also ...
(Date:2/5/2016)... , ... February 05, 2016 , ... Calls Blacklist has ... completely new user interface design and the developer has fixed known bugs within the ... want to on their phone while not consuming any of their device’s battery power ...
Breaking Medicine News(10 mins):
(Date:2/5/2016)... N.Y. , Feb. 5, 2016  Henry Schein, ... health care products and services to office-based dental, animal ... entered into an agreement to acquire a majority ownership ... supplies and equipment in Brazil . ... Headquartered in Blumenau, Brazil, Dental Cremer is the dental distribution ...
(Date:2/4/2016)... For hospitals considering enrollment in the Federal ... the program, the Health Resources and Services Administration,s (HRSA) ... Mega-Guidance , could have significant impact on plans and ... 2016. Essential Insights , Daniel Neal, ... the Mega-Guidance,s key proposed changes, including a new requirement ...
(Date:2/4/2016)... 4, 2016   Bernstein Liebhard LLP today announced ... United States District Court for the District of ... consisting of all persons or entities who purchased common shares ... INSY ) from March 3, 2015 through January 25, 2016 ... its officers with violations of the Securities Exchange Act of ...
Breaking Medicine Technology: