Navigation Links
A study demonstrates that ibuprofen improves bone repair after surgery or a fracture
Date:7/3/2012

A study conducted at the University of Granada hasdemonstrated that ibuprofen a non-steroidal anti-inflammatory drug (NSAID) has beneficial effects on bone repair after afracture or following bone surgery.

In vitro tests demonstrated that unlike other NSAIDs when a therapeutic dose of ibuprofen is administered, it has no negative effects on the proliferation and synthesis of obsteoblast osteocalcin, a cell which is directly involved in the formation and regeneration of bones.

Osteoblast cells are bone cells that synthesize the bone matrix. Consequently, osteoblasts play a major role in bone development, growth, maintenance and repair.

Positive Results

In an article recently published in the prestigious Journal of Bone and Mineral Metabolism, the University of Granada researchers report the positive effects of ibuprofen on bone repair. The researchers are members of the research group BIO277, which studies the effects of different pharmacological and non-pharmacological therapies on obsteoblast cells.

The primary author of this article, Concepcin Ruiz Rodrguez, a professor at the University of Granada Nursing Department states that "up to date, we had little information on the effects of ibuprofen on osteoblast cells". The University of Granada study demonstrates that a therapeutic dose of ibuprofen (5-25m.) does not inhibit the proliferation and synthesis of osteocalcinin the MG-63 cell line. However, when higher doses are administered (>25 m.) they may activate other cells, which might explain theexpression of membrane markers and the decrease in the phagocytic capacity.


'/>"/>

Contact: Concepcion Ruiz Rodriguez
crr@ugr.es
34-958-243-497
University of Granada
Source:Eurekalert

Page: 1

Related medicine news :

1. Study Suggests Vaccine May Help Kids With Brain Cancer
2. Study reveals how cancer drug causes diabetic-like state
3. Coffee Drinking in Pregnancy Wont Lead to Sleepless Baby: Study
4. Lower GI problems plague many with rheumatoid arthritis, Mayo Clinic study finds
5. Veggies Like Broccoli, Cabbage May Help Fight Breast Cancer: Study
6. No Added Cancer Risk From Hip Replacement Materials: Study
7. Reported Decline in U.S. Pneumonia Deaths May Be False: Study
8. Early Study Finds Some Promise for Lung Cancer Vaccine
9. Narcissists Often Ace Job Interviews, Study Finds
10. Sexual objectification of female artists in music videos exists regardless of race, MU study finds
11. Soy may alleviate hot flashes in menopause, large-scale study finds
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:6/24/2016)... ... 2016 , ... June 19, 2016 is World Sickle Cell Observance Day. In ... benefits of holistic treatments, Serenity Recovery Center of Marne, Michigan, has issued ... Sickle Cell Disease (SCD) is a disorder of the red blood cells, which can ...
(Date:6/24/2016)... ... June 24, 2016 , ... Dr. Amanda Cheng, ... treatment. Dr. Cheng has extensive experience with all areas of orthodontics, including robotic ... osteogenic orthodontics. , Micro-osteoperforation is a revolutionary adjunct to orthodontic treatment. It ...
(Date:6/24/2016)... ... June 24, 2016 , ... EB Medicine presented its first-ever ... Medicine conference in Ponte Vedra Beach, FL. The awards honor the outstanding work ... Practice and Pediatric Emergency Medicine Practice. , “With this award, we recognize ...
(Date:6/24/2016)... ... June 24, 2016 , ... National recruitment firm Slone Partners ... with extensive sequencing and genomics experience, as Vice President of North American Capital Sales ... be responsible for leading the sales team in the commercialization of the HTG EdgeSeq ...
(Date:6/24/2016)... ... 24, 2016 , ... Finally, a bruise cream that really works. Originally ... incorporated into the post-surgical treatment plans of a variety of other procedures including, but ... very effective for bruising and causes a rapid resolution of bruising and inflammatory changes ...
Breaking Medicine News(10 mins):
(Date:6/24/2016)... 24, 2016  Global Blood Therapeutics, Inc. (GBT) (NASDAQ: ... novel therapeutics for the treatment of grievous blood-based ... closing of its previously announced underwritten public offering ... public offering price of $18.75 per share. All ... by GBT. GBT estimates net proceeds from the ...
(Date:6/24/2016)... 24, 2016 The Academy of Managed Care ... that would allow biopharmaceutical companies to more easily ... make formulary and coverage decisions, a move that addresses ... medicines. The recommendations address restrictions in the ... the drug label, a prohibition that hinders decision makers ...
(Date:6/24/2016)... According to a new market ... Needles, Safety Pen Needles), Needle Length (4mm, 5mm, 6mm, ... of Purchase (Retail, Non-Retail) - Trends & Global Forecasts ... market for the forecast period of 2016 to 2021. ... by 2021 from USD 1.65 Billion in 2016, growing ...
Breaking Medicine Technology: